Non-traditional stable isotopes, with no clear definition yet, generally refer to isotopes beyond C, H, O, N, and S with small variations in natural stable isotopic composition, such as isotopes of transitional and heavy metal elements. With the rapid development in multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) technique, non-traditional stable isotopes have emerged as powerful tracers in geosciences, archaeology, anthropology, and environmental sciences. This article summarizes the recent advances in the analysis of non-traditional stable isotopes by MC-ICP-MS. We review recent efforts on improvement of the sensitivity of MC-ICP-MS and optimization of the sample preparation procedures. Special attention is paid to the “emerging” stable isotopes, e.g., vanadium (V), barium (Ba), potassium (K), platinum (Pt), palladium (Pd), silver (Ag), cerium (Ce), erbium (Er), and silicon (Si). We also introduce some novel aspects of application of non-traditional stable isotopes, e.g., in nanotechnology and environmental health studies. Finally, we discuss current challenges and give our perspectives in this active research area.

中文翻译：

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多收集器电感耦合等离子体质谱法分析非传统稳定同位素的最新进展

尚未明确定义的非传统稳定同位素，通常是指C，H，O，N和S以外的同位素，其天然稳定同位素组成变化很小，例如过渡金属和重金属元素的同位素。随着多收集器电感耦合等离子体质谱（MC-ICP-MS）技术的飞速发展，非传统稳定同位素已成为地球科学，考古学，人类学和环境科学中的强大示踪剂。本文总结了通过MC-ICP-MS分析非传统稳定同位素的最新进展。我们回顾了最近在改善MC-ICP-MS灵敏度和优化样品制备程序方面的工作。特别注意“新兴”的稳定同位素，例如钒（V），钡（Ba），钾（K），铂（Pt），钯（Pd），银（Ag），铈（Ce），（Er）和硅（Si）。我们还介绍了非传统稳定同位素应用的一些新颖方面，例如，在纳米技术和环境健康研究中。最后，我们讨论当前的挑战，并在这个活跃的研究领域中发表我们的观点。