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Therapeutic resistance: Ironing it out
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2017-08-11 00:00:00 , DOI: 10.1038/nrc.2017.71
Ulrike Harjes

Since mesenchymal-like properties in cancer cells are often associated with therapy resistance, Viswanathan et al. explored vulnerabilities of these cells. They identified an enzyme of the lipid peroxidase pathway, inhibition of which caused ferroptosis in a range of cancer types.

中文翻译:

治疗抵抗力:消除它

由于癌细胞中的间充质样特性通常与治疗耐药性相关,因此,Viswanathan等人。探索了这些细胞的脆弱性。他们确定了一种脂质过氧化物酶途径的酶,该酶的抑制导致多种癌症类型的肥大症。
更新日期:2017-08-24
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