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Inactivating BRAF Mutations Modulate RAS–MAPK Signaling
Cancer Discovery ( IF 28.2 ) Pub Date : 2017-08-11 , DOI: 10.1158/2159-8290.cd-rw2017-153 American Association for Cancer Research
中文翻译：
灭活BRAF突变调节RAS–MAPK信号传导
更新日期：2017-09-21
Cancer Discovery ( IF 28.2 ) Pub Date : 2017-08-11 , DOI: 10.1158/2159-8290.cd-rw2017-153 American Association for Cancer Research
Hypoactive BRAF mutants bind more tightly to active RAS and amplify ERK signaling.
中文翻译：
灭活BRAF突变调节RAS–MAPK信号传导
机能减退的BRAF突变体与活性RAS的结合更紧密，并放大ERK信号传导。
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