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Successful cure of extensively drug-resistant pulmonary tuberculosis in a young child
The Lancet Infectious Diseases ( IF 56.3 ) Pub Date : 2017-09-01 , DOI: 10.1016/s1473-3099(17)30457-7
Nicole Salazar-Austin , Ibukunoluwa Akinboyo , Sanjay K Jain

In The Lancet Infectious Diseases,1 we described a 2-year-old child from the USA who developed extensively drug-resistant pulmonary tuberculosis after a 3 month visit to India. She has been closely followed for 2 years after completing 18 months of directly observed therapy with an individualised drug regimen, including streptomycin (first 6 months), linezolid, para-aminosalicylic acid, cycloserine, and clofazimine. In the absence of clinical or microbiological markers, low-radiation exposure CT was used as a rapid biomarker to guide treatment.

中文翻译:

成功治愈幼儿广泛耐药的肺结核

《柳叶刀传染病》1)中,我们描述了一个来自美国的2岁孩子,他在访问印度3个月后发展为广泛耐药的肺结核。在完成18个月的个性化药物治疗直接观察治疗后(包括链霉素(头6个月),利奈唑胺,对氨基水杨酸,环丝氨酸和氯法齐明),她接受了2年的密切随访。在没有临床或微生物标志物的情况下,低辐射暴露CT被用作指导治疗的快速生物标志物。
更新日期:2017-08-24
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