Two new indanones, asperunguisones A-B (1–2), and three new diphenyl ethers, aspergillusethers B-D (3–5), were isolated from the soil-derived fungus Aspergillus unguis PSU-RSPG204 together with five known compounds including methyl orsellinate (6), pilobolusate (7), aspergillusphenol A (8), orcinol (9) and (+)-montagnitol (10). Their structures were established by spectroscopic evidence. Compound 8 showed moderate antibacterial activity against Staphylococcus aureus and methicillin-resistance S. aureus with MIC values of 16 and 8 μg/mL, respectively, whereas compound 5 exhibited moderate antifungal activity against Candida albicans (NCPF3153), flucytosine-resistant Cryptococcus neoformans (ATCC90113) and Penicillium marnefeii with the MIC values of 16, 8 and 16 μg/mL, respectively. For cytotoxic activity, compound 7 showed strong activity against the human oral carcinoma (KB) cell lines with an IC₅₀ value of 4.57 μM. In addition, all of them were inactive against African green monkey kidney fibroblast cells.

两个新的茚满酮，asperunguisones AB（1 - 2），以及三个新的二苯基醚，aspergillusethers BD（3 - 5），从该土壤衍生真菌分离曲霉unguis PSU-RSPG204连同5组已知的化合物，包括甲基orsellinate（6） ，匹波洛司酸酯（7），曲霉酚A（8），角蛋白醇（9）和（+）-山tag糖醇（10）。它们的结构是由光谱学证据确定的。化合物8表现出中等的抗菌活性对金黄色葡萄球菌和甲氧西林抗性金黄色葡萄球菌用16和8的MIC值 μ克/毫升，分别，而化合物5显示出中等抗真菌活性白色念珠菌（NCPF3153），耐氟胞嘧啶-新型隐球菌（ATCC90113）和青霉marnefeii与16,8和16的MIC值 μ g / mL。细胞毒活性，化合物7显示针对用的IC人口腔癌（KB）细胞系强的活性₅₀值的4.57  μ M.另外，他们都是针对非洲绿猴肾成纤维细胞无效。