Ag(I)-Catalyzed one-pot synthesis of 4-fluorobenzo[b][1,6]naphthyridines is described from o-alkynylquinolinyl aldehydes through imines in good to excellent yields. Selectfluor is used as a fluorinating reagent and the reaction proceeded at room temperature in an open atmosphere. Reactions employed in this synthesis method are also applied for the synthesis of 8-fluoro-1,6-naphthyridine, 7-fluoro-pyrazolo[4,3-c]pyridine and 4-fluoroisoquinoline derivatives. Standardized conditions were also applied on a gram scale reaction and gave a good yield of the product.

中文翻译：

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银（我）4-氟苯并[ -催化的单罐合成b ] [1,6]萘啶和4- fluoroisoquinolines经由与的Selectfluor炔烃的iminofluorination

从邻-炔基喹啉基醛到亚胺，以良好或极好的产率描述了Ag（I）催化的4-氟苯并[ b ] [1,6]萘啶的一锅合成。Selectfluor用作氟化剂，反应在室温下在开放气氛下进行。在该合成方法中采用的反应也用于合成8-氟-1，6-萘吡啶，7-氟-吡唑并[4，3- c ]吡啶和4-氟异喹啉衍生物。标准化条件也用于克规模的反应，并给出了良好的产物收率。