Small open reading frames (smORFs) of 100 codons or fewer are usually — if arbitrarily — excluded from proteome annotations. Despite this, the genomes of many metazoans, including humans, contain millions of smORFs, some of which fulfil key physiological functions. Recently, the transcriptome of Drosophila

中文翻译：

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小型开放阅读框的分类和功能

通常将100个密码子以下的小型开放阅读框（smORF）排除在蛋白质组注释之外（如果任意选择）。尽管如此，包括人类在内的许多后生动物的基因组仍包含数百万个smORF，其中一些具有关键的生理功能。最近，果蝇的转录组