Mutational profiling is increasingly performed to identify oncogenic alterations that can be matched to particular molecularly targeted drugs. This 'precision medicine' paradigm has resulted in improved outcomes for patients with specific molecular cancer subtypes, but the efficacy of many targeted therapies has been underwhelming. New

中文翻译：

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遗传学：条件选择决定了癌症进化的途径

越来越多地进行突变分析，以鉴定可与特定分子靶向药物匹配的致癌性改变。这种“精确医学”范式已为具有特定分子癌症亚型的患者改善了预后，但是许多靶向疗法的疗效却令人吃惊。新的