The ability to solubilize membrane proteins while retaining their native function is a persistent challenge. Re-engineering of the membrane protein DsbB into a soluble cytoplasmic version maintained its activity and enabled recompartmentalization of the periplasmic DsbAB disulfide bond–forming system.

中文翻译：

---

蛋白质工程：重定向膜机械

溶解膜蛋白同时保留其天然功能的能力是一个持续的挑战。将膜蛋白DsbB重新工程化为可溶的细胞质版本可以保持其活性，并使周质DsbAB二硫键形成系统重新分区。