A series of D-A’-π-A type photosensitizers AP3 and AP4 were designed and synthesized to show strong aggregation-induced far red and near infrared emission and very effective singlet oxygen generation simultaneously. In comparison with the most widely used photosensitizer Ce6 nanoparticles, AP4 nanoparticles showed over 10-fold higher fluorescence quantum yield, and more than 3-fold higher singlet oxygen generation efficiency, which have been successfully used for image-guided photodynamic anticancer therapy.

中文翻译：

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聚集诱导发射的高性能光敏剂，用于图像引导的光动力抗癌治疗

设计并合成了一系列D-A'-π-A型光敏剂AP3和AP4，以显示强聚集诱导的远红和近红外发射以及同时非常有效的单线态氧生成。与最广泛使用的光敏剂Ce6纳米颗粒相比，AP4纳米颗粒的荧光量子产率高出10倍以上，单线态氧产生效率高出3倍以上，已成功用于图像引导的光动力抗癌治疗。