Quantitative genetics has a long history in plants: It has been used to study specific biological processes, identify the factors important for trait evolution, and breed new crop varieties. These classical approaches to quantitative trait locus mapping have naturally improved with technology. In this review, we show how quantitative genetics has evolved recently in plants and how new developments in phenotyping, population generation, sequencing, gene manipulation, and statistics are rejuvenating both the classical linkage mapping approaches (for example, through nested association mapping) as well as the more recently developed genome-wide association studies. These strategies are complementary in most instances, and indeed, one is often used to confirm the results of the other. Despite significant advances, an emerging trend is that the outcome and efficiency of the different approaches depend greatly on the genetic architecture of the trait in the genetic material under study.

中文翻译：

---

定量遗传学的新策略和工具：如何从表型到基因型

数量遗传学在植物中有着悠久的历史：它已被用于研究特定的生物过程，确定对性状进化的重要因素，以及培育新的作物品种。这些经典的数量性状基因座定位方法随着技术的发展而自然地得到了改进。在这篇综述中，我们展示了数量遗传学最近如何在植物中进化，以及表型、群体生成、测序、基因操作和统计学的新发展如何使经典连锁映射方法（例如，通过嵌套关联映射）恢复活力作为最近发展的全基因组关联研究。在大多数情况下，这些策略是互补的，实际上，一种策略经常用于确认另一种策略的结果。尽管取得了重大进展，