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Guilt by Association: A Phenotype-Based View of the Plant Phosphoinositide Network
Annual Review of Plant Biology ( IF 23.9 ) Pub Date : 2017-04-28 , DOI: 10.1146/annurev-arplant-042916-041022
Katharina Gerth 1 , Feng Lin 1 , Wilhelm Menzel 1 , Praveen Krishnamoorthy 1 , Irene Stenzel 1 , Mareike Heilmann 1 , Ingo Heilmann 1
Affiliation  

Eukaryotic membranes contain small amounts of phospholipids that have regulatory effects on the physiological functions of cells, tissues, and organs. Phosphoinositides (PIs)-the phosphorylated derivatives of phosphatidylinositol-are one example of such regulatory lipids. Although PIs were described in plants decades ago, their contribution to the regulation of physiological processes in plants is not well understood. In the past few years, evidence has emerged that PIs are essential for plant function and development. Recently reported phenotypes associated with the perturbation of different PIs suggest that some subgroups of PIs influence specific processes. Although the molecular targets of PI-dependent regulation in plants are largely unknown, the effects of perturbed PI metabolism can be used to propose regulatory modules that involve particular downstream targets of PI regulation. This review summarizes phenotypes associated with the perturbation of the plant PI network to categorize functions and suggest possible downstream targets of plant PI regulation.

中文翻译:

关联内疚:基于表型的植物磷酸肌醇网络视图

真核细胞膜含有少量磷脂,对细胞、组织和器官的生理功能有调节作用。磷脂酰肌醇 (PI) - 磷脂酰肌醇的磷酸化衍生物 - 是此类调节脂质的一个例子。尽管 PI 几十年前在植物中被描述过,但它们对植物生理过程调节的贡献尚不清楚。在过去几年中,有证据表明 PI 对植物功能和发育至关重要。最近报道的与不同 PI 的扰动相关的表型表明,某些 PI 亚组影响特定过程。尽管植物中 PI 依赖性调控的分子靶点在很大程度上是未知的,PI 代谢紊乱的影响可用于提出涉及 PI 调节的特定下游目标的调节模块。本综述总结了与植物 PI 网络扰动相关的表型,以对功能进行分类并提出植物 PI 调控的可能下游目标。
更新日期:2017-04-28
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