Despite the widespread use of carbamates as a directing group in C–H bond-functionalization reactions, reductive removal of this directing group is not straightforward. Currently available methods are limited to nickel-catalyzed reactions using i PrMgX or hydrosilane as a reductant, leaving the functional group compatibility issue to be solved. Herein, we report rhodium-catalyzed reductive cleavage of aryl carbamates using i PrOH as a milder reductant.

中文翻译：

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使用异丙醇作为还原剂的铑催化还原裂解氨基甲酸芳基酯

尽管在 C-H 键官能化反应中广泛使用氨基甲酸酯作为导向基团，但还原去除该导向基团并不简单。目前可用的方法仅限于使用 i PrMgX 或氢硅烷作为还原剂的镍催化反应，留下官能团兼容性问题有待解决。在此，我们报告了使用 i PrOH 作为更温和的还原剂对氨基甲酸芳基酯进行铑催化的还原裂解。