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Palladium-Catalyzed Arylation of Benzylic C–H Bonds of Azaarylmethanes with Aryl Sulfides
Synlett ( IF 2 ) Pub Date : 2017-08-17 , DOI: 10.1055/s-0036-1589098
Ke Gao 1 , Keita Yamamoto 1 , Keisuke Nogi 1 , Hideki Yorimitsu 1
Affiliation  

Benzylic C–H arylation of azaarylmethanes with aryl sulfides has been developed by using a Pd-NHC catalyst and an amide base. Various azaarylmethanes and aryl sulfides were involved in the reaction to afford the corresponding diarylmethanes in good to excellent yields. Moreover, triarylmethane synthesis was accomplished through iterative arylations of 2- or 4-methylpyridine with two different aryl sulfides.

中文翻译:

钯催化的氮杂芳基甲烷的苄基 C-H 键与芳基硫化物的芳基化

已经通过使用 Pd-NHC 催化剂和酰胺碱开发了氮杂芳基甲烷与芳基硫化物的苄基 C-H 芳基化。各种氮杂芳基甲烷和芳基硫化物参与反应,以良好至极好的产率提供相应的二芳基甲烷。此外,三芳基甲烷的合成是通过 2- 或 4- 甲基吡啶与两种不同的芳基硫化物的迭代芳基化来完成的。
更新日期:2017-08-17
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