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Ready-to-use T cells for infection after stem-cell transplant
The Lancet Oncology ( IF 51.1 ) Pub Date : 2017-08-17 , DOI: 10.1016/s1470-2045(17)30625-3 Judith A Gilbert
The Lancet Oncology ( IF 51.1 ) Pub Date : 2017-08-17 , DOI: 10.1016/s1470-2045(17)30625-3 Judith A Gilbert
A new phase 2 trial suggests that cryopreserved virus-specific T cells (VSTs) prepared from third-party donors are a safe and effective treatment for recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT) who develop drug-refractory viral infections. Viral infection is a common, life-threatening complication for these patients, and drug treatment can be ineffective or have substantial side-effects.
中文翻译:
干细胞移植后即用型T细胞可用于感染
一项新的2期试验表明,由第三方供体制备的冷冻保存的病毒特异性T细胞(VST)对于发生药物难治性病毒感染的同种异体造血干细胞移植(allo-HSCT)受体是一种安全有效的治疗方法。病毒感染是这些患者常见的威胁生命的并发症,药物治疗可能无效或有重大副作用。
更新日期:2017-08-17
中文翻译:
干细胞移植后即用型T细胞可用于感染
一项新的2期试验表明,由第三方供体制备的冷冻保存的病毒特异性T细胞(VST)对于发生药物难治性病毒感染的同种异体造血干细胞移植(allo-HSCT)受体是一种安全有效的治疗方法。病毒感染是这些患者常见的威胁生命的并发症,药物治疗可能无效或有重大副作用。