The Streptococcus pneumoniae Invasive Disease network (SpIDnet) actively monitors populations in nine sites in seven European countries for invasive pneumococcal disease. Five sites use 13-valent pneumococcal conjugate vaccine (PCV13) alone and four use the ten-valent PCV (PCV10) and PCV13. Vaccination uptake is greater than 90% in six sites and 67-78% in three sites. We measured the effects of introducing high-valency PCVs on the incidence of invasive pneumococcal disease in children younger than 5 years.

中文翻译：

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高效率肺炎球菌结合疫苗对SpIDnet国家儿童侵袭性肺炎球菌疾病的影响：一项观察性多中心研究。

肺炎链球菌侵袭性疾病网络（SpIDnet）积极监测七个欧洲国家/地区中九个地点的人群是否患有侵袭性肺炎球菌疾病。五个地点仅使用13价肺炎球菌结合疫苗（PCV13），四个地点使用十价PCV（PCV10）和PCV13。六个地点的疫苗接种率大于90％，三个地点的疫苗接种率大于67-78％。我们测量了引入高价PCV对5岁以下儿童侵袭性肺炎球菌疾病发生率的影响。