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Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.
The Lancet ( IF 168.9 ) Pub Date : 2017-08-01 , DOI: 10.1016/s2213-2600(17)30207-2
MeiLan K Han 1 , Pedro M Quibrera 2 , Elizabeth E Carretta 2 , R Graham Barr 3 , Eugene R Bleecker 4 , Russell P Bowler 5 , Christopher B Cooper 6 , Alejandro Comellas 7 , David J Couper 2 , Jeffrey L Curtis 8 , Gerard Criner 9 , Mark T Dransfield 10 , Nadia N Hansel 11 , Eric A Hoffman 12 , Richard E Kanner 13 , Jerry A Krishnan 14 , Carlos H Martinez 1 , Cheryl B Pirozzi 13 , Wanda K O'Neal 2 , Stephen Rennard 15 , Donald P Tashkin 6 , Jadwiga A Wedzicha 16 , Prescott Woodruff 17 , Robert Paine 18 , Fernando J Martinez 19 ,
Affiliation  

Present treatment strategies to stratify exacerbation risk in patients with chronic obstructive pulmonary disease (COPD) rely on a history of two or more events in the previous year. We aimed to understand year to year variability in exacerbations and factors associated with consistent exacerbations over time.

中文翻译:

慢性阻塞性肺疾病患者的病情加重频率:SPIROMICS 队列分析。

目前对慢性阻塞性肺疾病(COPD)患者的急性加重风险进行分层的治疗策略依赖于前一年发生的两次或两次以上事件的病史。我们的目的是了解恶化的逐年变化以及与一段时间内持续恶化相关的因素。
更新日期:2017-08-10
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