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The Ribosome Holds the RNA Polymerase on Track in Bacteria
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2017-08-08 , DOI: 10.1016/j.tibs.2017.07.003 Bruno P. Klaholz
中文翻译:
核糖体使细菌中的RNA聚合酶保持正轨
更新日期:2017-08-08
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2017-08-08 , DOI: 10.1016/j.tibs.2017.07.003 Bruno P. Klaholz
The central dogma of molecular biology comprises two fundamental mechanistic steps of gene expression (transcription and translation), which, in bacteria, are coupled. A recent study provides structural insights into a supercomplex between the RNA polymerase and the ribosome, thus highlighting the synergy between two key macromolecular machineries in the cell.
中文翻译:
核糖体使细菌中的RNA聚合酶保持正轨
分子生物学的中心教条包括基因表达的两个基本机制步骤(转录和翻译),这些步骤在细菌中是耦合的。最近的一项研究提供了对RNA聚合酶和核糖体之间的超级复合体的结构见解,从而突显了细胞中两个关键的大分子机械之间的协同作用。