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Epigenetics: Therapy-induced transcription is cryptically widespread
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2017-07-14 , DOI: 10.1038/nrc.2017.57
Darren J. Burgess

A new study demonstrates that DNA methyltransferase inhibitors and histone deacetylase inhibitors induce widespread cryptic transcription from transposable elements that may contribute to cancer immunogenicity.

中文翻译:

表观遗传学:治疗性转录是秘密传播的

一项新的研究表明,DNA甲基转移酶抑制剂和组蛋白脱乙酰基酶抑制剂会诱导可转座因子广泛的隐性转录,可能有助于癌症的免疫原性。
更新日期:2017-08-10
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