Membrane transporter proteins are critical for cellular uptake and export of molecules, and are reported to function by a number of different molecular mechanisms. The new occluded state structure of the uracil transporter, UraA, from Escherichia coli, reveals that both coordinated movement of the two domains of a single protomer together with dimer formation are important for transport activity.

中文翻译：

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通过电梯运输需要两个人。

膜转运蛋白对于细胞摄取和输出分子至关重要，据报道其通过多种不同的分子机制发挥作用。来自大肠杆菌的尿嘧啶转运蛋白UraA的新的闭塞状态结构表明，单个原初蛋白两个结构域的协调运动以及二聚体的形成对于转运活性很重要。