The dichloromethane extract of the roots of Jatropha dioica afforded riolozatrione (1) and a C-6 epimer of riolozatrione, 6-epi-riolozatrione (2), as a new structure and only the second reported riolozane diterpenoid. The two known diterpenoids jatrophatrione (3) and citlalitrione (4) were also isolated and characterized. Both epimers 1 and 2 are genuine plant constituents, with 2 likely being the biosynthesis precursor of 1 due to the tendency for the quantitative transformation of 2 into 1 under base catalysis. The structural characterization and distinction of the stereoisomers utilized ¹H iterative full-spin analysis, yielding complete J-correlation maps that were represented as quantum interaction and linkage tables. The absolute configuration of compounds 1–4 was established by means of vibrational circular dichroism and via X-ray diffraction analysis for 1, 2, and 4. Additionally, the cytotoxic and antiherpetic in vitro activities of the isolates were evaluated.

中文翻译：

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麻风树麻疯树中第二个氟氮烷和其他二萜类化合物的立体化学

麻风树根的二氯甲烷提取物提供了新的结构，并提供了新的结构，并提供了新的结构，并提供了新的结构，其中包括了riolozatrione（1）和C-6异构体，riolozatrione（6- epi- riolozatrione）（2）。还分离并表征了两种已知的二萜类化合物麻风三酮（3）和瓜三酮（4）。差向异构体二者1和2是真正的植物成分，用2可能是生物合成的前体1由于对的定量转化的倾向2到1在碱催化下。立体异构体的结构表征和区别使用¹ H迭代全自旋分析，产生完整的J相关图，这些图表示为量子相互作用和键合表。化合物的绝对构型1 - 4通过振动圆二色的装置和经由用于X射线衍射分析，建立1，2，和4。另外，评估了分离物的细胞毒性和抗疱疹性体外活性。