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Polyhydroxyalkanoates as biomaterials
RSC Medicinal Chemistry ( IF 4.1 ) Pub Date : 2017-06-27 00:00:00 , DOI: 10.1039/c7md00252a
Bhagyashri S. Thorat Gadgil 1, 2, 3, 4 , Naresh Killi 1, 2, 3, 4 , Gundloori V. N. Rathna 1, 2, 3, 4
Affiliation  

Polyhydroxyalkanoates (PHAs) are biopolymers synthesized by bacteria under unbalanced growth conditions. These biopolymers are considered as potential biomaterials for future applications because they are biocompatible, biodegradable, and easy to produce and functionalize with strong mechanical strength. Currently, PHAs are being extensively innovated for biomedical applications due to their prerequisite properties. The wide range of biomedical applications includes drug delivery systems, implants, tissue engineering, scaffolds, artificial organ constructs, etc. In this article we review the utility of PHAs in various forms (bulk/nano) for biomedical applications so as to bring about the future vision for PHAs as biomaterials for the advancement of research and technology.

中文翻译:

聚羟基链烷酸酯作为生物材料

聚羟基链烷酸酯(PHA)是细菌在不平衡的生长条件下合成的生物聚合物。这些生物聚合物由于具有生物相容性,可生物降解,易于生产和具有强大的机械功能而被认为是未来应用的潜在生物材料。目前,由于其先决条件的特性,PHA正在生物医学应用方面进行广泛的创新。生物医学的广泛应用包括药物输送系统,植入物,组织工程,支架,人造器官构造等。在本文中,我们将综述各种形式(本体/纳米)的PHA在生物医学中的应用,以期实现生物医学应用。 PHA作为生物材料的未来愿景,以促进研究和技术的发展。
更新日期:2017-07-30
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