Synthesis of a cis-decalin moiety, containing an oxa-bridged cis-decalin ring system (11-oxatricyclo(5.3.1.^1,70^3,8)undecane), as a key intermediate of the total synthesis of luminamicin (1) was accomplished. One of the essential steps in our synthetic route is construction of a cis-decaline framework using a one-pot Michael addition-aldol reaction. Additionally, the bridged ether moiety was obtained by an intramolecular 1,6-oxa-Michael reaction of a conjugated aldehyde.

中文翻译：

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迈向光合霉素的全合成；一种厌氧抗生素：含有桥联醚部分的高度功能化的顺式十氢化萘的构建。

顺式萘烷的部分的合成，含有氧杂桥顺式-十氢萘环系统（11杂三环（5.3.1。^1,7 0 ^3,8）十一烷），如luminamicin的全合成的关键中间体（1 ）完成。我们合成路线中的基本步骤之一是使用一锅迈克尔加成-醛醇缩合反应构建顺式-十氢萘骨架。另外，通过共轭醛的分子内1，6-氧杂-迈克尔反应获得桥连的醚部分。