This review highlights the most significant examples of an emerging field in the design of highly selective anion receptors. To date, there has been remarkable progress in the binding and sensing of anions. This has been driven in part by the discovery of ways to construct effective anion binding receptors using the dominant N–H functional groups and neutral and cationic C–H hydrogen bond donors, as well as underexplored strong directional noncovalent interactions such as halogen-bonding and anion−π interactions. In this review, we will describe a new and promising strategy for constructing anion binding receptors with distinct advantages arising from their elaborate design, incorporating multiple binding sites able to interact cooperatively with anions through these different kinds of noncovalent interactions. Comparisons with control species or solely hydrogen-bonding analogues reveal unique characteristics in terms of strength, selectivity, and interaction geometry, representing important advances in the rising field of supramolecular chemistry.

中文翻译：

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基于组合非共价相互作用的阴离子识别策略

这篇综述突出了高选择性阴离子受体设计中新兴领域的最重要例子。迄今为止，在阴离子的结合和感测方面取得了显着进展。这部分是由于发现了使用占主导地位的N–H官能团以及中性和阳离子C–H氢键供体来构建有效的阴离子结合受体的方法，以及未充分开发的强方向性非共价相互作用（例如卤素键和氢键）的驱动。阴离子-π相互作用。在这篇综述中，我们将描述一种新的有前途的策略，用于构建具有独特优势的阴离子结合受体，这是由于其精心设计而产生的，该方法结合了能够通过这些不同类型的非共价相互作用与阴离子协同相互作用的多个结合位点。