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PET Tracer 18F-Fluciclovine Can Detect Histologically Proven Bone Metastatic Lesions: A Preclinical Study in Rat Osteolytic and Osteoblastic Bone Metastasis Models
Theranostics ( IF 12.4 ) Pub Date : 2017-05-15 , DOI: 10.7150/thno.19883
Shuntaro Oka , Masaru Kanagawa , Yoshihiro Doi , David M. Schuster , Mark M. Goodman , Hirokatsu Yoshimura

18F-Fluciclovine (trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid; anti-18F-FACBC) is a positron emission tomography (PET) tracer for diagnosing cancers (e.g., prostate and breast cancer). The most frequent metastatic organ of these cancers is bone. Fluciclovine-PET can visualize bony lesions in clinical practice; however, such lesions have not been described histologically.

中文翻译:

PET示踪剂18 F-氟西洛维汀可以检测组织学证明的骨转移性病变:大鼠溶骨和成骨细胞骨转移模型的临床前研究

18 F-Fluciclovine(反式-1-氨基-3- 18 F-fluorocyclobutanecarboxylic酸;- 18 F-FACBC)是一种正电子发射断层摄影术用于诊断癌症(例如,前列腺癌和乳腺癌)(PET)示踪剂。这些癌症中最常见的转移器官是骨骼。Fluciclovine-PET在临床实践中可以可视化骨性病变。然而,这种损伤尚未在组织学上描述。
更新日期:2017-07-01
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