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G Protein-Coupled Receptors: Crystal structure of glucagon family receptors
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2017-06-16 00:00:00 , DOI: 10.1038/nrd.2017.120
Sarah Crunkhorn

The class B G protein-coupled receptors (GPCRs), glucagon receptor (GCGR) and glucagon-like peptide 1 receptor (GLP1R), have key roles in glucose homeostasis and therefore represent valuable drug targets for diabetes. Zhang et al. now report the crystal structure of the full-length human GCGR in

中文翻译:

G蛋白偶联受体:胰高血糖素家族受体的晶体结构

BG类蛋白偶联受体(GPCR),胰高血糖素受体(GCGR)和胰高血糖素样肽1受体(GLP1R)在葡萄糖稳态中具有关键作用,因此代表了糖尿病的重要药物靶标。张等。现在报告全长人类GCGR的晶体结构
更新日期:2017-06-29
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