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Ageing: Old bone removal
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2017-06-16 00:00:00 , DOI: 10.1038/nrd.2017.123 M. Teresa Villanueva
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2017-06-16 00:00:00 , DOI: 10.1038/nrd.2017.123 M. Teresa Villanueva
Senescent cells (SNCs), which accumulate in many tissues with age, contribute to several age-related pathologies. Now, Elisseeff and colleagues have shown that the selective elimination of SNCs with a specific inhibitor (UBX0101) of the anti-apoptotic protein mouse double minute 2 (MDM2) can prevent and even
中文翻译:
老化:去除旧骨
衰老细胞(SNC)随着年龄的增长而在许多组织中积累,并导致了几种与年龄有关的病理。现在,Elisseeff及其同事已经表明,用抗凋亡蛋白小鼠doubleminute 2(MDM2)的特异性抑制剂(UBX0101)选择性消除SNC可以预防甚至预防
更新日期:2017-06-29
中文翻译:
老化:去除旧骨
衰老细胞(SNC)随着年龄的增长而在许多组织中积累,并导致了几种与年龄有关的病理。现在,Elisseeff及其同事已经表明,用抗凋亡蛋白小鼠doubleminute 2(MDM2)的特异性抑制剂(UBX0101)选择性消除SNC可以预防甚至预防