The carbon–carbon bond activation of organic molecules with transition metal complexes is an attractive transformation. These reactions form transition metal–carbon bonded intermediates, which contribute to fundamental understanding in organometallic chemistry. Alternatively, the metal–carbon bond in these intermediates can be further functionalized to construct new carbon–(hetero)atom bonds. This methodology promotes the concept that the carbon–carbon bond acts as a functional group, although carbon–carbon bonds are kinetically inert. In the past few decades, numerous efforts have been made to overcome the chemo-, regio- and, more recently, stereoselectivity obstacles. The synthetic usefulness of the selective carbon–carbon bond activation has been significantly expanded and is becoming increasingly practical: this technique covers a wide range of substrate scopes and transition metals.

中文翻译：

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铑卟啉配合物对脂肪族碳-碳键的选择性活化作用

具有过渡金属配合物的有机分子的碳-碳键活化是一个有吸引力的转变。这些反应形成过渡金属-碳键合的中间体，有助于有机金属化学的基本理解。另外，这些中间体中的金属-碳键可以进一步官能化，以构建新的碳-（杂）原子键。尽管碳-碳键在动力学上是惰性的，但这种方法提倡了碳-碳键充当官能团的概念。在过去的几十年中，已经做出了许多努力来克服化学，区域和最近的立体选择性障碍。选择性碳-碳键活化的合成用途已大大扩展，并且变得越来越实用：