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SnapShot: Immune Checkpoint Inhibitors
Cancer Cell ( IF 50.3 ) Pub Date : 2017-06-12 00:00:00 , DOI: 10.1016/j.ccell.2017.05.010
Gabriel Abril-Rodriguez , Antoni Ribas

Immunotherapy has changed the landscape of cancer treatment. Checkpoint blockade therapies unleash breaks in the immune system and induce long-lasting responses. However, a significant number of patients do not respond (innate resistance), and a subset progress after responding (acquired resistance). A better understanding of the molecular mechanisms underlying checkpoint blockade therapies will facilitate the design of novel strategies to treat and prevent resistance. To view this SnapShot, open or download the PDF.

中文翻译:

SnapShot:免疫检查点抑制剂

免疫疗法改变了癌症治疗的面貌。检查站封锁疗法释放了免疫系统的破坏并引起了持久的反应。但是,相当多的患者没有反应(先天抵抗),有一部分患者在反应后进展(获得性抵抗)。对检查点封锁疗法的分子机制有一个更好的了解,将有助于设计治疗和预防耐药性的新策略。要查看此SnapShot,请打开或下载PDF。
更新日期:2017-06-13
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