Despite being the main effectors of the innate immune response and programmed to detect and eliminate mutated cells, macrophages can change their phenotype and become pro-tumorigenic in response to cues from the tumour. Given their position within the tumour mass, tumour-associated macrophages (TAMs) are an

中文翻译：

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抗癌治疗：重新培养巨噬细胞

尽管巨噬细胞是先天性免疫反应的主要效应物，并被编程用来检测和消除突变的细胞，但巨噬细胞仍可以改变其表型，并响应来自肿瘤的线索而成为促肿瘤的。鉴于它们在肿瘤块中的位置，与肿瘤相关的巨噬细胞（TAM）是一种