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Copper(I)-mediated carboamination of vinyl azides by aryldiazonium salts: synthesis of N2-substituted 1,2,3-triazoles
Chemical Communications ( IF 4.9 ) Pub Date : 2017-05-18 00:00:00 , DOI: 10.1039/c7cc02391j
Zhenhua Liu 1, 2, 3, 4, 5 , Huimin Ji 1, 2, 3, 4, 5 , Wen Gao 1, 2, 3, 4, 5 , Guangyu Zhu 1, 2, 3, 4, 5 , Lili Tong 1, 2, 3, 4, 5 , Fengcai Lei 1, 2, 3, 4, 5 , Bo Tang 1, 2, 3, 4, 5
Affiliation  

A copper(I)-mediated carboamination cascade reaction between vinyl azides and aryldiazonium salts is described. Functionally diverse N2-substituted 1,2,3-triazoles were obtained in moderate to good yields through novel difunctionalization of vinyl azides by aryldiazonium salt sources. This method has a wide scope, good functional-group tolerance and insensitivity to an ambient atmosphere.

中文翻译:

芳基重氮盐铜(I)介导的叠氮化物的碳氨化:N 2取代的1,2,3-三唑的合成

描述了乙烯基叠氮化物和芳基重氮盐之间的铜(I)介导的碳氨化级联反应。通过芳基重氮盐源对叠氮化物进行新的双官能化,以中等至良好的产率获得了功能多样的N 2-取代的1,2,3-三唑。该方法适用范围广,对官能团的耐受性好,对周围环境不敏感。
更新日期:2017-05-26
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