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An Unsaturated Quinolone N-Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2017-05-23 03:10:24 , DOI: 10.1002/anie.201704012
Dávid Szamosvári 1 , Thomas Böttcher 1
Affiliation  

Chemical interactions of competing bacteria have major implications for health and disease of their human host. In their Communication (DOI: 10.1002/anie.201702944), D. Szamosvári and T. Böttcher report an unsaturated quinolone N-oxide produced by Pseudomonas aeruginosa with unprecedented efficacy and activity against Staphylococcus aureus affecting both growth and virulence. These results provide insight into a major metabolite by which P. aeruginosa modulates growth and behavior of its competitors.

中文翻译:

铜绿假单胞菌的不饱和喹诺酮N-氧化物调节金黄色葡萄球菌的生长和毒力。

竞争细菌的化学相互作用对人类宿主的健康和疾病具有重大影响。D.Szamosvári和T.Böttcher在其交流中(DOI:10.1002 / anie.201702944)报告了一种由铜绿假单胞菌产生的不饱和喹诺酮N-氧化物,其对金黄色葡萄球菌具有前所未有的功效和活性,同时影响生长和毒力。这些结果为铜绿假单胞菌调节其竞争者的生长和行为的主要代谢产物提供了见识。
更新日期:2017-05-24
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