当前位置: X-MOL 学术Nat. Biomed. Eng. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency
Nature Biomedical Engineering ( IF 28.1 ) Pub Date : 2017-05-10 00:00:00 , DOI: 10.1038/s41551-017-0066
Bin Li , Weiyu Zhao , Xiao Luo , Xinfu Zhang , Chenglong Li , Chunxi Zeng , Yizhou Dong

An array of chemically engineered CRISPR RNAs and AsCpf1 messenger RNAs leads to improvements in gene-cutting efficiency up to about 300% with respect to unmodified CRISPR RNA and plasmid-encoding AsCpf1.

中文翻译:

工程CRISPR–Cpf1 crRNA和mRNA最大化基因组编辑效率

与未经修饰的CRISPR RNA和编码质粒的AsCpf1相比,一系列化学工程化的CRISPR RNA和AsCpf1 Messenger RNA导致基因切割效率提高了约300%。
更新日期:2017-05-18
down
wechat
bug