Acquired Mycobacterium tuberculosis resistance to the commonly used antibiotic ethionamide (ETH) is mediated by mutations in the bacterial enzymatic pathway that is required for biological activation of the drug. Here, Blondiaux et al. identify a series of spiroisoxazoline compounds — named small molecules

中文翻译：

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抗生素：抗逆性

获得性结核分枝杆菌对常用抗生素乙硫酰胺（ETH）的耐药性是由药物生物激活所需的细菌酶促途径突变介导的。在这里，Blondiaux等。鉴定一系列螺异恶唑啉化合物—命名为小分子