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In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2017-04-17 00:00:00 , DOI: 10.1038/nnano.2017.57 Tyrel T. Smith , Sirkka B. Stephan , Howell F. Moffett , Laura E. McKnight , Weihang Ji , Diana Reiman , Emmy Bonagofski , Martin E. Wohlfahrt , Smitha P. S. Pillai , Matthias T. Stephan
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2017-04-17 00:00:00 , DOI: 10.1038/nnano.2017.57 Tyrel T. Smith , Sirkka B. Stephan , Howell F. Moffett , Laura E. McKnight , Weihang Ji , Diana Reiman , Emmy Bonagofski , Martin E. Wohlfahrt , Smitha P. S. Pillai , Matthias T. Stephan
DNA-carrying nanoparticles can efficiently introduce leukaemia-targeting CAR genes into T cell nuclei, thereby inducing long-term disease remission.
中文翻译:
使用合成的DNA纳米载体原位编程白血病特异性T细胞
携带DNA的纳米颗粒可以有效地将靶向白血病的CAR基因引入T细胞核,从而诱导长期疾病缓解。
更新日期:2017-05-18
中文翻译:
使用合成的DNA纳米载体原位编程白血病特异性T细胞
携带DNA的纳米颗粒可以有效地将靶向白血病的CAR基因引入T细胞核,从而诱导长期疾病缓解。