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Cyclopropanation Strategies in Recent Total Syntheses
Chemical Reviews ( IF 62.1 ) Pub Date : 2017-05-03 00:00:00 , DOI: 10.1021/acs.chemrev.6b00798
Christian Ebner 1 , Erick M. Carreira 1
Affiliation  

Complex molecular architectures containing cyclopropanes present significant challenges for any synthetic chemist. This review aims to highlight the strategic considerations for introduction of the cyclopropane motif in a collection of recent total syntheses. At first, an overview of the most important and widely used cyclopropanation techniques is presented, followed by a discussion of elegant approaches and clever solutions that have been developed to enable the synthesis of various unique cyclopropane natural products or use of cyclopropanes as versatile strategic intermediates.

中文翻译:

最近的总合成中的环丙烷化策略

对于任何合成化学家而言,含有环丙烷的复杂分子结构都面临着重大挑战。这篇综述旨在强调在最近的全部合成中引入环丙烷基序的战略考虑。首先,介绍了最重要和广泛使用的环丙烷化技术,然后讨论了优雅的方法和巧妙的解决方案,这些方法和方法已经开发出来,可以合成各种独特的环丙烷天然产物或将环丙烷用作通用的战略中间体。
更新日期:2017-05-03
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