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Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2017-04-10 00:00:00 , DOI: 10.1038/nnano.2017.47 Peter Popp Wibroe , Aaron C. Anselmo , Per H. Nilsson , Apoorva Sarode , Vivek Gupta , Rudolf Urbanics , Janos Szebeni , Alan Christy Hunter , Samir Mitragotri , Tom Eirik Mollnes , Seyed Moein Moghimi
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2017-04-10 00:00:00 , DOI: 10.1038/nnano.2017.47 Peter Popp Wibroe , Aaron C. Anselmo , Per H. Nilsson , Apoorva Sarode , Vivek Gupta , Rudolf Urbanics , Janos Szebeni , Alan Christy Hunter , Samir Mitragotri , Tom Eirik Mollnes , Seyed Moein Moghimi
The transitional link from robust clearance of intravenously injected nanoparticles by strategically placed macrophages in systemic circulation to adverse haemodynamic reactions can be overcome by changing nanoparticle geometry or by prior nanoparticle attachment to erythrocytes
中文翻译：
通过形状修饰和附着到红细胞绕过对纳米颗粒的不良注射反应
可以通过改变纳米粒子的几何形状或通过事先将纳米粒子附着在红细胞上来克服从静脉内注射的纳米粒子通过策略性放置在系统循环中的巨噬细胞对静脉注射纳米粒子的强劲清除到不利的血液动力学反应之间的过渡联系
更新日期：2017-04-11
中文翻译：
通过形状修饰和附着到红细胞绕过对纳米颗粒的不良注射反应
可以通过改变纳米粒子的几何形状或通过事先将纳米粒子附着在红细胞上来克服从静脉内注射的纳米粒子通过策略性放置在系统循环中的巨噬细胞对静脉注射纳米粒子的强劲清除到不利的血液动力学反应之间的过渡联系
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