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Fragment-based phenotypic screening is a hit
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2017-03-30 , DOI: 10.1038/nrd.2017.56
Monya Baker

Libraries of functionalized small-molecule fragments that can be screened in whole cells could take phenotypic drug discovery to the next level, providing new opportunities against undertargeted proteins.

中文翻译:

基于片段的表型筛选很成功

可以在全细胞中筛选的功能化小分子片段文库可以将表型药物发现提高到一个新水平,为针对靶标不足的蛋白质提供了新的机会。
更新日期:2017-04-11
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