A selective and light-up fluorescent probe for [small beta]-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative,Chemical Communications

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A selective and light-up fluorescent probe for [small beta]-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative
Chemical Communications ( IF 4.9 ) Pub Date : 2017-03-29 00:00:00 , DOI: 10.1039/c7cc00249a
Guoyu Jiang _{1,

2,

3,

4} , Guanjie Zeng _{1,

2,

3,

4} , Wenping Zhu _{1,

2,

3,

4} , Yongdong Li _{1,

2,

3,

4} , Xiaobiao Dong _{4,

5,

6,

7,

8} , Guanxin Zhang _{4,

5,

6,

7,

8} , Xiaolin Fan _{1,

2,

3,

4} , Jianguo Wang _{1,

2,

3,

4} , Yongquan Wu _{1,

2,

3,

4} , Ben Zhong Tang _{9,

10,

11,

12,

13}

Affiliation

An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of [small beta]-galactosidase in living cells. The applicability of TPE-Gal in imaging endogenous [small beta]-galactosidase activity was confirmed...

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