Correlated Mass Spectrometry and Confocal Microscopy Imaging Verifies Dual-Targeting Action of an Organoruthenium Anticancer Complex,Chemical Communications

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Correlated Mass Spectrometry and Confocal Microscopy Imaging Verifies Dual-Targeting Action of an Organoruthenium Anticancer Complex
Chemical Communications ( IF 4.9 ) Pub Date : 2017-03-22 00:00:00 , DOI: 10.1039/c7cc01503h
Suyan Liu _{1,

2,

3,

4,

5} , Wei Zheng _{1,

2,

3,

4,

5} , Kui Wu _{1,

2,

3,

4,

5} , Yu Lin _{1,

2,

3,

4,

5} , Feifei Jia _{1,

2,

3,

4,

5} , Yang Zhang _{1,

2,

3,

4,

5} , Zhaoying Wang _{1,

2,

3,

4,

5} , Qun Luo _{1,

2,

3,

4,

5} , Yao Zhao _{1,

2,

3,

4,

5} , Fuyi Wang _{1,

2,

3,

4,

5}

Affiliation

An addressable single cell imaging strategy combining ToF-SIMS and confocal fluorescence microscopy imaging has been developed, and sucessfully applied to visualize the subcellular distribution of an organoruthenium anticancer complex, [([small eta]⁶-benzene)Ru(N,N-L)Cl]⁺...

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