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The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography
Chemical Communications ( IF 4.9 ) Pub Date : 2017-03-21 00:00:00 , DOI: 10.1039/c6cc10150j
Matthew P. Sullivan 1, 2, 3, 4, 5 , Michael Groessl 6, 7, 8 , Samuel M. Meier 9, 10, 11, 12 , Richard L. Kingston 2, 3, 4, 5 , David C. Goldstone 2, 3, 4, 5 , Christian G. Hartinger 1, 2, 3, 4
Affiliation  

Metalation of hen egg white lysozyme (HEWL) with organometallics was studied with physicochemical methods in solid state, solution and the gas phase. While metalation did not affect the crystal structure...

中文翻译:

鸡蛋蛋白溶菌酶的金属化会影响蛋白质的稳定性,如离子淌度质谱,差示扫描量热法和X射线晶体学所示

通过物理化学方法研究了固态,溶液和气相中有机金属对鸡蛋清溶菌酶(HEWL)的金属化作用。虽然金属化并没有影响晶体结构。
更新日期:2017-03-24
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