The significance of chirality transfer is not only involved in biological systems, such as the origin of homochiral structures in life but also in man-made chemicals and materials. How the chiral bias transfers from molecular level (molecular chirality) to helical chain (conformational chirality) and then to helical superstructure or phase (hierarchical chirality) from self-assembly is vital for the chemical and biological processes in nature, such as communication, replication, and enzyme catalysis. In this Account, we summarize the methodologies for the examination of homochiral evolution at different length scales based on our recent studies with respect to the self-assembly of chiral polymers and chiral block copolymers (BCPs*).

中文翻译：

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自组装手性聚合物和嵌段共聚物的手性演化

手性转移的重要性不仅涉及生物系统，例如生命中同质手性结构的起源，还涉及人造化学物质和材料。手性偏向如何从分子水平（分子手性）转移到螺旋链（构象手性），然后从自组装转移到螺旋超结构或相（递阶手性），这对于自然界中的化学和生物过程（如通讯，复制）至关重要和酶催化。在此帐户中，我们基于对手性聚合物和手性嵌段共聚物（BCPs *）的自组装的最新研究，总结了在不同长度尺度上检查同手性演化的方法。