Daphniphyllum is an evergreen species known since 1826. After initial systematic investigations, more than 320 members of this family have been isolated, which comprise complex and fascinating structures. Unique azapolycyclic architectures containing one or more quaternary stereocenters render these alkaloids synthetically challenging. This review covers efforts toward the synthesis of Daphniphyllum alkaloids spanning the period from 2005 to the beginning of 2016, including reported biological activities as well as the isolation of new members of this genus.

中文翻译：

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瑞香生物碱化学的最新进展†

虎皮是常绿物种自1826年已知的初始系统的调查后，该家族的多于320组的成员已被分离，其包括复杂的和引人入胜的结构。包含一个或多个四级立体中心的独特的杂多环结构使这些生物碱在合成上具有挑战性。本文综述了对合成的努力虎皮包括报道的生物活性，以及该属的新成员的隔离生物碱跨越从2005年至2016年年初。