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Antipsychotic Medications and Mortality in Children and Young Adults. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-29 Wayne A Ray,D Catherine Fuchs,Mark Olfson,Stephen W Patrick,C Michael Stein,Katherine T Murray,James Daugherty,William O Cooper
Importance Dose-related effects of antipsychotic medications may increase mortality in children and young adults. Objective To compare mortality for patients aged 5 to 24 years beginning treatment with antipsychotic vs control psychiatric medications. Design, Setting, and Participants This was a US national retrospective cohort study of Medicaid patients with no severe somatic illness or schizophrenia
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Accurate Machine Learning Prediction in Psychiatry Needs the Right Kind of Information. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-29 Brian Kraus,Kruthika Sampathgiri,Vijay A Mittal
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Transdiagnostic Ecological Momentary Intervention for Improving Self-Esteem in Youth Exposed to Childhood Adversity: The SELFIE Randomized Clinical Trial. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-29 Ulrich Reininghaus,Maud Daemen,Mary Rose Postma,Anita Schick,Iris Hoes-van der Meulen,Nele Volbragt,Dorien Nieman,Philippe Delespaul,Lieuwe de Haan,Marieke van der Pluijm,Josefien Johanna Froukje Breedvelt,Mark van der Gaag,Ramon Lindauer,Jan R Boehnke,Wolfgang Viechtbauer,David van den Berg,Claudi Bockting,Therese van Amelsvoort
Importance Targeting low self-esteem in youth exposed to childhood adversity is a promising strategy for preventing adult mental disorders. Ecological momentary interventions (EMIs) allow for the delivery of youth-friendly, adaptive interventions for improving self-esteem, but robust trial-based evidence is pending. Objective To examine the efficacy of SELFIE, a novel transdiagnostic, blended EMI for
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Attention-Deficit/Hyperactivity Disorder Medications and Long-Term Risk of Cardiovascular Diseases. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-22 Le Zhang,Lin Li,Pontus Andell,Miguel Garcia-Argibay,Patrick D Quinn,Brian M D'Onofrio,Isabell Brikell,Ralf Kuja-Halkola,Paul Lichtenstein,Kristina Johnell,Henrik Larsson,Zheng Chang
Importance Use of attention-deficit/hyperactivity disorder (ADHD) medications has increased substantially over the past decades. However, the potential risk of cardiovascular disease (CVD) associated with long-term ADHD medication use remains unclear. Objective To assess the association between long-term use of ADHD medication and the risk of CVD. Design, Setting, and Participants This case-control
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Long-Term Cardiovascular Effects of Medications for Attention-Deficit/Hyperactivity Disorder-Balancing Benefits and Risks of Treatment. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-22 Samuele Cortese,Cristiano Fava
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Pregnancy and Postpartum Drug Overdose Deaths in the US Before and During the COVID-19 Pandemic. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-22 Beth Han,Wilson M Compton,Emily B Einstein,Emerald Elder,Nora D Volkow
Importance Knowledge about characteristics of US pregnancy-associated decedents is needed to guide responses. Objective To examine individual sociodemographic characteristics and residing county's health care resources and socioeconomic factors among pregnancy-associated overdose decedents in comparison with obstetric decedents and overdose decedents who were not pregnant in the past year. Design,
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Mapping Psychomotor Behavior in the Brain. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-22 Sebastian Walther,Stephan Heckers
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Neighborhood Disadvantage and Autism Spectrum Disorder in a Population With Health Insurance. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Xin Yu,Md Mostafijur Rahman,Sarah A Carter,Jane C Lin,Ting Chow,Frederick W Lurmann,Jiu-Chiuan Chen,Mayra P Martinez,Joel Schwartz,Sandrah P Eckel,Zhanghua Chen,Rob McConnell,Anny H Xiang,Daniel A Hackman
Importance Family socioeconomic status has been associated with autism spectrum disorder (ASD) diagnoses. Less is known regarding the role of neighborhood disadvantage in the United States, particularly when children have similar access to health insurance. Objective To evaluate the association between neighborhood disadvantage and the diagnosis of ASD and potential effect modification by maternal
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Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Anil N Makam
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The Role of Socioeconomic Position in the Association Between Mental Disorders and Mortality: A Systematic Review and Meta-Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Danni Chen,Linda Ejlskov,Lisbeth Mølgaard Laustsen,Nanna Weye,Christine Leonhard Birk Sørensen,Natalie C Momen,Julie Werenberg Dreier,Yan Zheng,Astrid Jensen Damgaard,John J McGrath,Henrik Toft Sørensen,Oleguer Plana-Ripoll
Importance Studies are lacking summarizing how the association between mental disorders and mortality varies by socioeconomic position (SEP), particularly considering different aspects of SEP, specific types of mental disorders, and causes of death. Objective To investigate the role of SEP in the association between mental disorders and mortality and the association between SEP and mortality among
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Climate Events, Displacement, and Mental Health-Uprooted. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Lisa R Fortuna,Aida Jimenez,Michelle V Porche
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Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Benjamin Dralle,Robert J Morgan
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Concerns Regarding Strength of Conclusions in Systematic Review and Meta-Analysis of Neuroradiological Abnormalities in First-Episode Psychosis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-15 Malcolm Forbes,Stephen Stuckey,Steve Kisely
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Generalizability and Out-of-Sample Predictive Ability of Associations Between Neuromelanin-Sensitive Magnetic Resonance Imaging and Psychosis in Antipsychotic-Free Individuals. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-08 Kenneth Wengler,Seth C Baker,Anastasia Velikovskaya,Alissa Fogelson,Ragy R Girgis,Francisco Reyes-Madrigal,Seonjoo Lee,Camilo de la Fuente-Sandoval,Najate Ojeil,Guillermo Horga
Importance The link between psychosis and dopaminergic dysfunction is established, but no generalizable biomarkers with clear potential for clinical adoption exist. Objective To replicate previous findings relating neuromelanin-sensitive magnetic resonance imaging (NM-MRI), a proxy measure of dopamine function, to psychosis severity in antipsychotic-free individuals in the psychosis spectrum and to
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Public Sector Learning Health Care Systems-Improving Patient Experience, Workforce Well-Being, and Recovery Outcomes. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-08 Carlos Blanco,Robert K Heinssen,Wendy N Tenhula
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Patterns of Neural Network Functional Connectivity Associated With Mania/Hypomania and Depression Risk in 3 Independent Young Adult Samples. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Maya C Schumer,Michele A Bertocci,Haris A Aslam,Simona Graur,Genna Bebko,Richelle S Stiffler,Alexander S Skeba,Tyler J Brady,Osasumwen E Benjamin,Yiming Wang,Henry W Chase,Mary L Phillips
Importance Mania/hypomania is the pathognomonic feature of bipolar disorder (BD). Established, reliable neural markers denoting mania/hypomania risk to help with early risk detection and diagnosis and guide the targeting of pathophysiologically informed interventions are lacking. Objective To identify patterns of neural responses associated with lifetime mania/hypomania risk, the specificity of such
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Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Gita A Pathak,Kritika Singh,Karmel W Choi,Yu Fang,Manuela R Kouakou,Younga Heather Lee,Xiang Zhou,Lars G Fritsche,Frank R Wendt,Lea K Davis,Renato Polimanti
Importance Posttraumatic stress disorder (PTSD) has been reported to be a risk factor for several physical and somatic symptoms. However, the genetics of PTSD and its potential association with medical outcomes remain unclear. Objective To examine disease categories and laboratory tests from electronic health records (EHRs) that are associated with PTSD polygenic scores. Design, Setting, and Participants
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Perinatal Mental Health Outcomes Following Natural Disasters. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Karen G Martínez-González,Evangelia Morou-Bermúdez,Carmen J Buxó
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Transition to Schizophrenia Spectrum Disorder Following Emergency Department Visits Due to Substance Use With and Without Psychosis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Daniel T Myran,Lyndsay D Harrison,Michael Pugliese,Marco Solmi,Kelly K Anderson,Jess G Fiedorowicz,Christopher M Perlman,Colleen Webber,Yaron Finkelstein,Peter Tanuseputro
Importance Episodes of substance-induced psychosis are associated with increased risk of developing a schizophrenia spectrum disorder. However, there are limited data on the transition risk for substance use without psychosis. Objectives To quantify the risk of transition to schizophrenia spectrum disorder following an incident emergency department (ED) visit for (1) substance-induced psychosis and
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Etiologic Studies of Premenstrual Disorders Require Prospective Confirmation of Affective Cyclicity-Reply. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Piotr Jaholkowski,Marit Haram,Ole A Andreassen
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Sexual Dysfunction in Schizophrenia: A Systematic Review and Meta-Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Théo Korchia,Vincent Achour,Mélanie Faugere,Ali Albeash,Dong Keon Yon,Laurent Boyer,Guillaume Fond
Importance In individuals with schizophrenia, antipsychotic-induced dysfunctions are frequent but often underexplored in clinical practice. Objective To synthetize the data of observational studies exploring the prevalence of sexual dysfunction in individuals with schizophrenia-spectrum disorders as well as associated factors. Data Sources A systematic literature search without language or time restrictions
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Etiologic Studies of Premenstrual Disorders Require Prospective Confirmation of Affective Cyclicity. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Arianna Di Florio,Chloe Apsey,Tory A Eisenlohr-Moul
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Stress as a Risk Factor for Mental Disorders in a Gendered Environment. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Carolyn M Mazure,Mathilde M Husky,Robert H Pietrzak
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Brain Networks and Adolescent Alcohol Use. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Sarah W Yip,Sarah D Lichenstein,Qinghao Liang,Bader Chaarani,Alecia Dager,Godfrey Pearlson,Tobias Banaschewski,Arun L W Bokde,Sylvane Desrivières,Herta Flor,Antoine Grigis,Penny Gowland,Andreas Heinz,Rüdiger Brühl,Jean-Luc Martinot,Marie-Laure Paillère Martinot,Eric Artiges,Frauke Nees,Dimitri Papadopoulos Orfanos,Tomáš Paus,Luise Poustka,Sarah Hohmann,Sabina Millenet,Juliane H Fröhner,Michael N Smolka
Importance Alcohol misuse in adolescence is a leading cause of disability and mortality in youth and is associated with higher risk for alcohol use disorder. Brain mechanisms underlying risk of alcohol misuse may inform prevention and intervention efforts. Objective To identify neuromarkers of alcohol misuse using a data-driven approach, with specific consideration of neurodevelopmental sex differences
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Written Exposure Therapy Finds Solid Footing Alongside First-Line Psychotherapies for Posttraumatic Stress Disorder. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Charles T Taylor,Murray B Stein
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Implications of the Network Theory for the Treatment of Mental Disorders: A Secondary Analysis of a Randomized Clinical Trial. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Lea Schumacher,Jan Philipp Klein,Moritz Elsaesser,Martin Härter,Martin Hautzinger,Elisabeth Schramm,Levente Kriston
Importance Conceptualizing mental disorders as latent entities has been challenged by the network theory of mental disorders, which states that psychological problems are constituted by a network of mutually interacting symptoms. While the implications of the network approach for planning and evaluating treatments have been intensively discussed, empirical support for the claims of the network theory
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Written Exposure Therapy vs Prolonged Exposure Therapy in the Treatment of Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Denise M Sloan,Brian P Marx,Ron Acierno,Michael Messina,Wendy Muzzy,Matthew W Gallagher,Scott Litwack,Colleen Sloan
Importance Evidence-based treatments for posttraumatic stress disorder (PTSD) exist, but all require 8 to 15 sessions and thus are less likely to be completed than brief treatments. Written exposure therapy (WET) is a brief and efficacious treatment that has not been directly compared with prolonged exposure therapy (PE), a more time-intensive, exposure-based treatment. Objective To determine whether
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Evaluation of Post-COVID-19 Cognitive Dysfunction: Recommendations for Researchers. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Jaqueline H Becker,Tracy D Vannorsdall,Sara L Weisenbach
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Effects of 12 Weeks of At-Home, Application-Based Exercise on Health Care Workers' Depressive Symptoms, Burnout, and Absenteeism: A Randomized Clinical Trial. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Vincent Gosselin Boucher,Brook L Haight,Benjamin A Hives,Bruno D Zumbo,Aaliya Merali-Dewji,Stacey Hutton,Yan Liu,Suzanne Nguyen,Mark R Beauchamp,Agnes T Black,Eli Puterman
Importance During the COVID-19 pandemic, health care workers (HCWs) reported a significant decline in their mental health. One potential health behavior intervention that has been shown to be effective for improving mental health is exercise, which may be facilitated by taking advantage of mobile application (app) technologies. Objective To determine the extent to which a 12-week app-based exercise
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Alcohol Cue Processing in Co-Occurring Bipolar Disorder and Alcohol Use Disorder. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 William H Mellick,Bryan K Tolliver,Helena M Brenner,Raymond F Anton,James J Prisciandaro
Importance Reward circuitry dysfunction is a candidate mechanism of co-occurring bipolar disorder and alcohol use disorder (BD + AUD) that remains understudied. This functional magnetic resonance imaging (fMRI) research represents the first evaluation of alcohol cue reward processing in BD + AUD. Objective To determine how alcohol cue processing in individuals with BD + AUD may be distinct from that
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Perinatal Depression Screening Among Sexual Minority Women. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Leiszle Lapping-Carr,Ashley Dennard,Katherine L Wisner,S Darius Tandon
Importance A substantial number of births in the US are to sexual minority women (17% based on a nationally representative survey), yet there is little research on perinatal depression screening rates or symptom endorsement among sexual minority women (including women who identify as lesbian, bisexual, queer, pansexual, asexual, demisexual, and kinky as well as other-identified women who have sex with
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Substances Detected During Coroner Postmortem Toxicology Analyses in Poisoning- and Nonpoisoning-Related Suicides. JAMA Psychiatry (IF 25.8) Pub Date : 2023-11-01 Jessy S Lim,Nicholas A Buckley,Rose Cairns,Jennifer Schumann,Andrea L Schaffer,Kate M Chitty
Importance Determining the association between drug use and suicide is complicated but can help to inform targeted suicide prevention strategies. Objective To examine the substances prevalent in poisoning- and nonpoisoning-related suicides in Australia. Design, Setting, and Participants This was a multiple-year, cross-sectional study of suicides from July 2013 to October 2019 in Australia with toxicology
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Metabolomic Biomarker Signatures for Bipolar and Unipolar Depression. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-25 Jakub Tomasik,Scott J Harrison,Nitin Rustogi,Tony Olmert,Giles Barton-Owen,Sung Yeon Sarah Han,Jason D Cooper,Pawel Eljasz,Lynn P Farrag,Lauren V Friend,Emily Bell,Dan Cowell,Sabine Bahn
Importance Bipolar disorder (BD) is frequently misdiagnosed as major depressive disorder (MDD) because of overlapping symptoms and the lack of objective diagnostic tools. Objective To identify a reproducible metabolomic biomarker signature in patient dried blood spots (DBSs) that differentiates BD from MDD during depressive episodes and assess its added value when combined with self-reported patient
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Intrauterine Growth and Offspring Neurodevelopmental Traits: A Mendelian Randomization Analysis of the Norwegian Mother, Father and Child Cohort Study (MoBa). JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-25 Shannon D'Urso,Gunn-Helen Moen,Liang-Dar Hwang,Laurie J Hannigan,Elizabeth C Corfield,Helga Ask,Stefan Johannson,Pål Rasmus Njølstad,Robin N Beaumont,Rachel M Freathy,David M Evans,Alexandra Havdahl
Importance Conventional epidemiological analyses have suggested that lower birth weight is associated with later neurodevelopmental difficulties; however, it is unclear whether this association is causal. Objective To investigate the relationship between intrauterine growth and offspring neurodevelopmental difficulties. Design, Setting, and Participants MoBa is a population-based pregnancy cohort that
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Treatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-25 Luis C Farhat,José M Flores,Victor J Avila-Quintero,Guilherme V Polanczyk,Andrea Cipriani,Toshi A Furukawa,Michael H Bloch,Samuele Cortese
Importance Stimulants (methylphenidate and amphetamines) are often prescribed at unlicensed doses for adults with attention-deficit/hyperactivity disorder (ADHD). Whether dose escalation beyond US Food and Drug Administration recommendations is associated with positive risk benefits is unclear. Objective To investigate the impact, based on averages, of stimulant doses on treatment outcomes in adults
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Choosing Between Ketamine and Electroconvulsive Therapy for Outpatients With Treatment-Resistant Depression-Advantage Ketamine? JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-25 Sanjay J Mathew,Manish K Jha,Amit Anand
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Ketamine for Depression-Knowns, Unknowns, Possibilities, Barriers, and Opportunities. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-25 Chittaranjan Andrade
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Estimated Average Treatment Effect of Psychiatric Hospitalization in Patients With Suicidal Behaviors: A Precision Treatment Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-18 Eric L Ross,Robert M Bossarte,Steven K Dobscha,Sarah M Gildea,Irving Hwang,Chris J Kennedy,Howard Liu,Alex Luedtke,Brian P Marx,Matthew K Nock,Maria V Petukhova,Nancy A Sampson,Nur Hani Zainal,Erik Sverdrup,Stefan Wager,Ronald C Kessler
Importance Psychiatric hospitalization is the standard of care for patients presenting to an emergency department (ED) or urgent care (UC) with high suicide risk. However, the effect of hospitalization in reducing subsequent suicidal behaviors is poorly understood and likely heterogeneous. Objectives To estimate the association of psychiatric hospitalization with subsequent suicidal behaviors using
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Psychotherapies for Generalized Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-18 Davide Papola,Clara Miguel,Mariacristina Mazzaglia,Pamela Franco,Federico Tedeschi,Sara A Romero,Anushka R Patel,Giovanni Ostuzzi,Chiara Gastaldon,Eirini Karyotaki,Mathias Harrer,Marianna Purgato,Marit Sijbrandij,Vikram Patel,Toshi A Furukawa,Pim Cuijpers,Corrado Barbui
Importance Generalized anxiety disorder (GAD) is one of the most common mental disorders in adults. Psychotherapies are among the most recommended treatments for GAD, but which should be considered as first-line treatment needs to be clarified. Objective To use a network meta-analysis to examine the short- and long-term associations of different psychotherapies with outcomes of effectiveness and acceptability
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Use of Lysergic Acid Diethylamide by Major Depression Status. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-11 Claire A Walsh,Lauren Gorfinkel,Dvora Shmulewitz,Malki Stohl,Deborah S Hasin
Importance Renewed interest in the clinical potential of hallucinogens may lead people with depression to a generally more positive view of the use of lysergic acid diethylamide (LSD). Therefore, past-year LSD use among people with depression may be increasing in prevalence. Objective To assess time trends in the prevalence of past-year nonmedical LSD use by past-year major depression status and the
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Prognostic Risk Factors in Randomized Clinical Trials of Face-to-Face and Internet-Based Psychotherapy for Depression: A Systematic Review and Meta-Regression Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-11 Mariia Merzhvynska,Markus Wolf,Tobias Krieger,Thomas Berger,Thomas Munder,Birgit Watzke
Importance Variables such as severe symptoms, comorbidity, and sociodemographic characteristics (eg, low educational attainment or unemployment) are associated with a poorer prognosis in adults treated for depressive symptoms. The exclusion of patients with a poor prognosis from RCTs is negatively associated with the generalizability of research findings. Objective To compare the prognostic risk factors
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Climate Change and Mental Health-Time to Act Now. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-04 Pim Cuijpers,Manasi Kumar,Eirini Karyotaki
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Prevalence of Autism Among Medicaid-Enrolled Adults. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-04 Eric Rubenstein,Salina Tewolde,Amy Michals,Matthew Fox,Na Wang
Importance The reported prevalence of autism in children has consistently risen over the past 20 years. The concurrent implications for the adult Medicaid system, which insures autistic adults due to low income or disability, have not been studied. Objective To estimate the prevalence of adults identified as autistic in Medicaid claims data and to examine the prevalence by year, age, and race and ethnicity
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Individual-Level Risk Prediction of Return to Use During Opioid Use Disorder Treatment. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-04 Sean X Luo,Daniel J Feaster,Ying Liu,Raymond R Balise,Mei-Chen Hu,Layla Bouzoubaa,Gabriel J Odom,Laura Brandt,Yue Pan,Yih-Ing Hser,Paul VanVeldhuisen,Felipe Castillo,Anna R Calderon,John Rotrosen,Andrew J Saxon,Roger D Weiss,Melanie Wall,Edward V Nunes
Importance No existing model allows clinicians to predict whether patients might return to opioid use in the early stages of treatment for opioid use disorder. Objective To develop an individual-level prediction tool for risk of return to use in opioid use disorder. Design, Setting, and Participants This decision analytical model used predictive modeling with individual-level data harmonized in June
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Mental Health in a Changing Planet. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-04 Claudia Lugo-Candelas
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Prefrontal γ-Aminobutyric Acid Levels in Never-Medicated Individuals With Chronic Schizophrenia. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Francisco Reyes-Madrigal,Luz González-Manríquez,Francisco Martínez de Velasco,Ricardo Mora-Durán,Richard A E Edden,Pablo León-Ortiz,Camilo de la Fuente-Sandoval
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Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Gunter Schumann,Ole A Andreassen,Tobias Banaschewski,Vince D Calhoun,Nicholas Clinton,Sylvane Desrivieres,Ragnhild Eek Brandlistuen,Jianfeng Feng,Soeren Hese,Esther Hitchen,Per Hoffmann,Tianye Jia,Viktor Jirsa,Andre F Marquand,Frauke Nees,Markus M Nöthen,Gaia Novarino,Elli Polemiti,Markus Ralser,Michael Rapp,Kerstin Schepanski,Tamara Schikowski,Mel Slater,Peter Sommer,Bernd Carsten Stahl,Paul M Thompson
Importance Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual. How these environmental factors influence the brain, behavior, and mental illness is not well known
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Leveraging Health Linkage Data From the UK Biobank-With Great Power Comes Great Responsibility-Reply. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Najaf Amin,Rima Kaddurah-Daouk,Cornelia M van Duijn
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Leveraging Health Linkage Data From the UK Biobank-With Great Power Comes Great Responsibility. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Daniel E Radford-Smith,Daniel C Anthony
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High-Deductible Health Plans' Impact on Mental Health and Substance Use Disorder Treatments-Balancing Cost and Care. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Matthew D Eisenberg,Colleen L Barry
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Association of Genetically Predicted Insomnia With Risk of Sepsis: A Mendelian Randomization Study. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Marianne S Thorkildsen,Lise T Gustad,Randi M Mohus,Stephen Burgess,Tom I L Nilsen,Jan K Damås,Tormod Rogne
Importance Insomnia has been associated with altered inflammatory response as well as increased risk of infections and sepsis in observational studies. However, these studies are prone to bias, such as residual confounding. To further understand the potential causal association between insomnia and sepsis risk, a 2-sample Mendelian randomization (MR) approach should be explored. Objective To evaluate
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Dynamic Prediction of Outcomes for Youth at Clinical High Risk for Psychosis: A Joint Modeling Approach. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Michelle A Worthington,Jean Addington,Carrie E Bearden,Kristin S Cadenhead,Barbara A Cornblatt,Matcheri Keshavan,Cole A Lympus,Daniel H Mathalon,Diana O Perkins,William S Stone,Elaine F Walker,Scott W Woods,Yize Zhao,Tyrone D Cannon
Importance Leveraging the dynamic nature of clinical variables in the clinical high risk for psychosis (CHR-P) population has the potential to significantly improve the performance of outcome prediction models. Objective To improve performance of prediction models and elucidate dynamic clinical profiles using joint modeling to predict conversion to psychosis and symptom remission. Design, Setting,
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A Collaborative Effort to Establish Common Metrics for Use in Mental Health. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Gregory K Farber,Suzanne Gage,Danielle Kemmer
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Rural-Urban Disparities in Video Telehealth Use During Rapid Mental Health Care Virtualization Among American Indian/Alaska Native Veterans. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Isabelle S Kusters,Amber B Amspoker,Kristen Frosio,Stephanie C Day,Giselle Day,Anthony Ecker,Julianna Hogan,Jan A Lindsay,Jay Shore
Importance American Indian/Alaska Native veterans experience a high risk for health inequities, including mental health (MH) care access. Rapid virtualization of MH care in response to the COVID-19 pandemic facilitated care continuity across the Veterans Health Administration (VHA), but the association between virtualization of care and health inequities among American Indian/Alaska Native veterans
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Open Notes Use in Psychiatry-The Need for Multilevel Efforts in Research and Practice. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Elizabeth B Matthews,Yaara Zisman-Ilani
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Effects of a Contextual Adaptation of the Unified Protocol in Multiple Emotional Disorders in Individuals Exposed to Armed Conflict in Colombia: A Randomized Clinical Trial. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Leonidas Castro-Camacho,David H Barlow,Nicolás García,Todd J Farchione,Fabio Idrobo,Michel Rattner,Diana M Quant,Laura González,Julián D Moreno
Importance A transdiagnostic treatment, the Unified Protocol, is as effective as single diagnostic protocols in comorbid emotional disorders in clinical populations. However, its effects on posttraumatic stress disorder and other emotional disorders in individuals living in war and armed conflict contexts have not been studied. Objective To evaluate the efficacy of a cultural and contextual adaptation
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Intersectional Prevalence of Suicide Ideation, Plan, and Attempt Based on Gender, Sexual Orientation, Race and Ethnicity, and Rurality. JAMA Psychiatry (IF 25.8) Pub Date : 2023-10-01 Lauren N Forrest,Ariel L Beccia,Cara Exten,Sarah Gehman,Emily B Ansell
Importance Suicidal thoughts and behaviors (STBs) are major public health problems, and some social groups experience disproportionate STB burden. Studies assessing STB inequities for single identities (eg, gender or sexual orientation) cannot evaluate intersectional differences and do not reflect that the causes of inequities are due to structural-level (vs individual-level) processes. Objective To
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Emotional Experience of People With Schizophrenia and People at Risk for Psychosis: A Meta-Analysis. JAMA Psychiatry (IF 25.8) Pub Date : 2023-09-27 Marcel Riehle,Alexandra Straková,Tania M Lincoln
Importance Psychotic symptoms are associated with subjective reports of aberrant emotion, such as excessive fear or anhedonia, but whether these aberrations reflect aberrant emotional experience of normative stimuli is uncertain both for individuals with schizophrenia and those at risk for psychosis. Objective To provide a meta-analysis of study samples of emotional experience in individuals with schizophrenia
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Evaluating the Liability of Antidepressants to Induce Mania in Children and Adolescents With Depression. JAMA Psychiatry (IF 25.8) Pub Date : 2023-09-27 Krista F Huybrechts,Mark Olfson