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  • Fat: so much more than just fat
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-22
    Robert Stirrups
    更新日期:2017-09-23
  • Bollywood's dialogue with diabetes: sweet and subtle
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-22
    Sanghamitra Pati

    Mainstream Indian cinema fails to engage with the country's increasing burden of diabetes. Sanghamitra Pati reports.

    更新日期:2017-09-23
  • Disentangling the association between diabetes and bone disease – Authors' reply
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-10-01
    Vikram V Shanbhogue, Stinus Hansen, Morten Frost, Kim Brixen, Anne P Hermann

    We appreciate the interest in our Personal View and thank Katrine Hygum and colleagues for their comments. We also recognise the complexity and multifactorial nature of diabetic bone disease, but still find strong indications for the key role of microvascular disease in diabetic bone disease. Although the results of the Danish register-based study1 with data from more than 14 000 patients with diabetes suggested that neither diabetic eye disease nor neuropathy added to the risk of fractures, presence of diabetic kidney disease doubled the risk of fracture in comparison with patients with diabetes who had no microvascular disease.

    更新日期:2017-09-20
  • Disentangling the association between diabetes and bone disease
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-10-01
    Katrine Hygum, Bente Lomholt Langdahl, Jakob Starup-Linde

    We welcome the timely Personal View on bone disease in diabetes by Vikram Shanbhogue and colleagues.1 We believe that the increased fracture risk in patients with diabetes is caused by multiple factors including insulin deficiency, hyperinsulinaemia, an altered incretin response, obesity, use of glucose-lowering drugs, use of antihypertensive and lipid-lowering drugs, comorbidities, falls, and diabetes complications. We suggest that interplay of these factors causes the increased fracture risk in patients with diabetes and that diabetic bone disease is not predominantly attributable to the presence of microvascular disease.

    更新日期:2017-09-20
  • Denosumab treatment in postmenopausal women with osteoporosis – Authors' reply
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-10-01
    Henry G Bone, Rachel B Wagman, Nicola Pannacciulli, Socrates Papapoulos

    We note Yu Zhang and Rongrui Tang's criticism of the use of a placebo control group in the original FREEDOM trial,1 which was followed by a 7-year open-label extension, the subject of our Article. FREEDOM was initiated in 2004, was conducted in compliance with Food and Drug Administration and European Medicines Agency regulatory guidance,2,3 and was reviewed and approved by the Ethics Committee or equivalent for every participating site. In addition, all participants were given calcium and vitamin D supplementation, and the protocol provided for discontinuation of study medication and initiation of appropriate treatment for participants who experienced an osteoporosis-related fracture or a significant decrease in bone mineral density.

    更新日期:2017-09-20
  • Denosumab treatment in postmenopausal women with osteoporosis
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-10-01
    Paul de Boissieu, Thierry Trenque

    In The Lancet Diabetes & Endocrinology, Henry Bone and colleagues reported results of denosumab administration for up to 7 or 10 years in postmenopausal women with osteoporosis.1 Participants who had completed the randomised FREEDOM trial were offered to participate in the open-label, 7-year extension, receiving 60 mg of denosumab subcutaneously every 6 months.

    更新日期:2017-09-20
  • Denosumab treatment in postmenopausal women with osteoporosis
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-10-01
    Yu Zhang, Rongrui Tang

    In their 7-year study extension1 on the prevention of fractures with the human monoclonal antibody denosumab, Henry Bone and colleagues report low rates of adverse events and low fracture incidences compared with those observed during the original FREEDOM trial. The study has limitations that ought to be pointed out.

    更新日期:2017-09-20
  • Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-15
    Marc S Sabatine, Lawrence A Leiter, Stephen D Wiviott, Robert P Giugliano, Prakash Deedwania, Gaetano M De Ferrari, Sabina A Murphy, Julia F Kuder, Ioanna Gouni-Berthold, Basil S Lewis, Yehuda Handelsman, Armando Lira Pineda, Narimon Honarpour, Anthony C Keech, Peter S Sever, Terje R Pedersen
    更新日期:2017-09-15
  • PCSK9 inhibition and type 2 diabetes
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-15
    Luca A Lotta, Simon J Griffin

    The focus of cardiovascular disease prevention has shifted from normalisation of risk factors to absolute risk reduction. Reducing LDL cholesterol concentration by 1 mmol/L for about 5 years is consistently associated with a 23–25% lowered risk of major cardiovascular events, with statin and non-statin therapies alike, irrespective of baseline LDL cholesterol concentration.1 In high-income and middle-income countries, statins are now routinely recommended as first-line LDL cholesterol-lowering therapy for people with 10-year modelled risk above, somewhat arbitrary, country-specific thresholds defined by economic and clinical considerations.

    更新日期:2017-09-15
  • Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    Mark O Goodarzi
    更新日期:2017-09-15
  • Progress and challenges in anti-obesity pharmacotherapy
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    Daniel H Bessesen, Luc F Van Gaal
    更新日期:2017-09-15
  • Metabolically healthy obesity: the low-hanging fruit in obesity treatment?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    Norbert Stefan, Hans-Ulrich Häring, Matthias B Schulze
    更新日期:2017-09-15
  • Precision medicine: diagnosis and management of obesity
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    Gema Frühbeck, Dimitrios N Kiortsis, Victoria Catalán
    更新日期:2017-09-15
  • Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-13
    Rury R Holman, Ruth L Coleman, Juliana C N Chan, Jean-Louis Chiasson, Huimei Feng, Junbo Ge, Hertzel C Gerstein, Richard Gray, Yong Huo, Zhihui Lang, John J McMurray, Lars Rydén, Stefan Schröder, Yihong Sun, Michael J Theodorakis, Michal Tendera, Lynne Tucker, Jaakko Tuomilehto, Yidong Wei, Wenying Yang, Duolao Wang, Dayi Hu, Changyu Pan, Joanne Keenan, Joanne Milton, Zoe Doran, Chris Bray, Jean L Rouleau, Jane Collier, Stuart Pocock, Eberhard Standl, Karl Swedberg, Jianping Weng, Dong Zhao, Mark C Petrie, Eugene Connolly, Pardeep Jhund, Michael MacDonald, Rachel C Myles, Rong Bai, Jing Li, Zhaoping Liu, Zhenyu Liu, Dantao Peng, Qiguang Tong, Chunxue Wang, Xiaowei Yan, Yuqing Zhang, Jingmin Zhou, Naveed Sattar, Miles Fisher, John R Petrie, M Angelyn Bethel, Wen Xu, Sarah Hearn, Anurag Kappai, Shu-Yi Su, Winitha Liyanage, Sanjoy Paul, Emanuela Pozzi, Arne Ring, Rajbir Athwal, Priyanka Batra, Andrea Ferch, Natasha Groves, Irene Kennedy, Olga Nawalaniec, Yash Patel, Rachel Roberts, Victoria Rush, Jayne Starrett, Jennifer Tang, Jing Bi, Zhe Jiang, Hua Wei, Xiaoshuai Wei, Xuan Zhang, Jun Yin, Yu Sun, Rong Hu, Yang Liu, Jianjing Long, Yuefeng Long, Guofang Qiao, Haoyi Qiao, Xiaochun Sun, Yucheng Zhang, Jing Zhou, Bangning Wang, Bin Chen, Lili Deng, Xiaoning Han, Taohong Hu, Qi Hua, Yanming Huo, Hongmei Li, Hongwei Li, Lihua Liu, Juming Lu, Changsheng Ma, Jianjun Peng, Lin Pi, Bin Wang, Guanglin Wei, Ming Yang, Shuyang Zhang, Likun Zhang, Xia Zhao, Yujie Zhou, Libin Shi, Mingsheng Wang, Lirong Wu, Lei Han, Ronghong Liao, Boli Ran, Qiang She, Jiancong Tan, Mei Xia, Chengming Yang, Lianglong Chen, Shangquan Xiong, Ling Yu, Xiaodong Pu, Yan Wang, Qiang Xie, Cibin Chen, Jiyan Chen, Yugang Dong, Zhaohui Wu, Yong Yuan, Wanxing Zhou, Shuxian Zhou, Xiaochao Chen, Chun Wu, Aidong Zhang, Zicheng Li, Shayi Lai, Jin Yang, Jinru Wei, Riyu Kuang, Zilin Zhao, Guoqiang Zhong, Xufen Cao, Yuming Hao, Gang Liu, Dongmei Wang, Hui Fang, Lingjun Kong, Haitao Li, Changqing Wang, Li'na Wang, Xueqi Li, Pingshuan Dong, Shouyan Zhang, Xincan Liu, Yulan Zhao, Hengliang Liu, Ye Gu, Yuhua Liao, Xi Su, Daowen Wang, Hairong Wang, Bo Yang, Ying Guo, Ding'an Ouyang, Tianlun Yang, Yumin Zhang, Yajun Han, Xuefeng Lin, Ruiping Zhao, Ronghai Man, Rongwen Bian, Xu Biao, Buaijiaer Hasimu, Hui Jin, Ping Liu, Jiangyi Yu, Hang Zhang, Chongli Xu, Yan Guo, Ke Lv, Yijia Tao, Xin Xu, Zhenyu Yang, Dongye Li, Chunmei Qi, Guohui Zhang, Xiang Gu, Lang Hong, Ling Hu, Juxiang Li, Ping Yang, Bin Liu, Gang Wang, Hailong Lin, Jun Liu, Shuying Zhang, Ping Han, Yuanzhe Jin, Ling Li, Zhanquan Li, Hong Luan, Mei Song, Li Xue, Yu Hua, Dongwu Liu, Zuyi Yuan, Jixian Ye, Feng Gao, Jinhua Feng, A'li Wang, Shengming Ye, Xiaoyan Li, Guohai Su, Shufang Zhang, Zishan Hou, Wenbin Jiang, Changyong Zhou, Yanping Wang, Wenbo Qi, Xiaomei Bao, Bo Feng, Hui Gong, Shuiming Gu, Mingjun Gu, Xingui Guo, Ben He, Ying Huang, Jinfa Jiang, Yifeng Jiang, Huigen Jin, Yuehua Li, Qiliang Liu, Guoping Lu, Peizhi Miao, Yongwen Qin, Bin Wang, Yuanming Wang, Shiyao Wu, Yawei Xu, Jin Ma, Xiaoping Chen, Xiumin Liu, Jianing Tang, Jingping Wang, Xiaoping Chen, Jianhong Tao, Jun Zhang, Tingjie Zhang, Decai Li, Xinping Du, Tiemin Jiang, Jingna Lin, Chengzhi Lu, Hongjun Ma, Bo Gao, Xukun Guo, Tong Li, Shaoxiong Zheng, Zhongcheng Li, Shuwu Zhao, Qiang Qiu, Kaili Li, Junming Liu, Baopeng Tang, Zhanjun Yuan, Jianhua Zhou, Wenwei Bai, Tao Guo, Ge Zhang, Hong Zhang, Yinglu Hao, Guosheng Fu, Lijiang Tang
    更新日期:2017-09-14
  • Break point instead of ACE: acarbose, post-load glycaemic excursions, and cardiovascular events
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-13
    Michael A Nauck, Juris J Meier
    更新日期:2017-09-14
  • Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    Paresh Dandona, Chantal Mathieu, Moshe Phillip, Lars Hansen, Steven C Griffen, Diethelm Tschöpe, Fredrik Thorén, John Xu, Anna Maria Langkilde, Joseph Proietto, Stephen Stranks, Roger Chen, David O'Neal, Alexia Pape, Mark Forbes, Claire Morbey, Anton Luger, Ursula Hanusch, Christoph Schnack, Evelyn Fliesser-Goerzer, Bertram Hoelzl, Christoph Ebenbichler, Rudolf Prager, Luc Van Gaal, Chris Vercammen, Andre Scheen, Chantal Mathieu, Francis Duyck, Frank Nobels, Johannes Ruige, Naresh Aggarwal, Vincent Woo, Bruno St-Pierre, Richard Dumas, Irene Hramiak, Thomas Elliott, Troels Krarup Hansen, Jan Erik Henriksen, Jeppe Gram, Aina Lihn, Jens Bruun, Juha Saltevo, Jyrki Taurio, Jorma Strand, Timo Valle, Sakari Nieminen, Kirsi Pietilainen, Bruno Guerci, Samy Hadjadj, Bertrand Cariou, Bruno Verges, Sophie Borot, Alfred Penfornis, Thomas Schaum, Diethelm Tschoepe, Cornelia Marck, Thomas Horacek, Ludger Rose, Gerhard Klausmann, Joerg Luedemann, Steffi Appelt, Ulrich Aigner, Rolf Goebel, Thomas Behnke, Anette-Gabriele Ziegler, Eva Peterfai, Zsuzsanna Kerenyi, Tamas Oroszlan, Gyula G. Kiss, Laszlo Konyves, Gyorgyi Piros, Moshe Phillip, Ofri Mosenzon, Naim Shehadeh, Faiad Adawi, Julio Wainstein, Francesco Dotta, Piermarco Piatti, Stefano Genovese, Agostino Consoli, Paolo Di Bartolo, Edoardo Mannucci, Carla Giordano, Annunziata Lapolla, Carlos Aguilar, Alberto Esteban, Bazzoni Ruiz, Guillermo Mondragon Ramirez, Emilia Pelayo Orozco, Carlos Alejandro, Stobschinski de Alba, Carlos Medina Pech, Jose Garza Ruiz, Leobardo Sauque Reyna, Guillermo Llamas Esperon, Luis Alejandro Nevarez Ruiz, Maricela Vidrio Velazquez, Fernando Flores Lozano, Jose Gerardo Gonzalez Gonzalez, Pedro Alberto Garcia-Hernandez, Roberto Araujo-Silva, Efrain Villeda - Espinosa, Cristina Mistodie, Daniela Popescu, Ciprian Constantin, Alina Nicolau, Bogdan Popa, Romulus Timar, Cristian Serafinceanu, Ella Pintilei, Alfonso Soto, Margarita Gimenez, Juan Merino, Cristobal Morales, Pedro Mezquita, Johan Jendle, Bengt-Olov Tengmark, Jan Eriksson, Magnus Londahl, Bjorn Eliasson, Anthony Gunstone, Simon Heller, Ken Darzy, Peter Mansell, Melanie Davies, Rory Reed, Duncan Browne, Hamish Courtney, Wayne Turner, Mark Blagden, Rory McCrimmon, Richard Bergenstal, Wendy Lane, Kathryn Lucas, Alexander White, Shichun Bao, Judith White, Curtis Jantzi, Neda Rasouli, William Ervin, Lorena Lewy-Alterbaum, Yehuda Handelsman, Bresta Miranda-Palma, Alan Cleland, Raymond Fink, Helena Rodbard, Samer Nakhle, Craig Greenberg, Alan Schorr, Harold Bays, Debra Simmons, Eric Klein, Laurie Kane, Norman Fishman, Eli Ipp, Satish Garg, Anuj Bhargava, Michelle Zaniewski Singh, Julio Rosenstock, James Thrasher, Mark Warren, Laura Young, Vanita Aroda, Jeremy Pettus, David Liljenquist, Robert Busch, Paresh Dandona, Jonathan Wise, David Kayne, William Biggs
    更新日期:2017-09-14
  • SGLT2 inhibitors in type 1 diabetes: knocked down, but up again?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-14
    John R Petrie

    Life expectancy is significantly reduced in people with type 1 diabetes, and quality of life is frequently affected by eye, kidney, foot, and cardiovascular disease. Achieving and sustaining control of blood glucose to reduce the risk of these complications is a substantial challenge for many affected individuals. One strategy under investigation is the repurposing of drugs used in other conditions as adjunct therapy.1 An ideal adjunct agent—added to insulin therapy—would provide a sustained reduction in blood glucose concentrations without increasing hypoglycaemia, while preventing insulin-induced weight gain and improving cardiovascular outcomes.

    更新日期:2017-09-14
  • Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-13
    Olga Vaccaro, Maria Masulli, Antonio Nicolucci, Enzo Bonora, Stefano Del Prato, Aldo P Maggioni, Angela A Rivellese, Sebastiano Squatrito, Carlo B Giorda, Giorgio Sesti, Paolo Mocarelli, Giuseppe Lucisano, Michele Sacco, Stefano Signorini, Fabrizio Cappellini, Gabriele Perriello, Anna Carla Babini, Annunziata Lapolla, Giovanna Gregori, Carla Giordano, Laura Corsi, Raffaella Buzzetti, Gennaro Clemente, Graziano Di Cianni, Rossella Iannarelli, Renzo Cordera, Olga La Macchia, Chiara Zamboni, Cristiana Scaranna, Massimo Boemi, Ciro Iovine, Davide Lauro, Sergio Leotta, Elisabetta Dall'Aglio, Emanuela Cannarsa, Laura Tonutti, Giuseppe Pugliese, Antonio C Bossi, Roberto Anichini, Francesco Dotta, Antonino Di Benedetto, Giuseppe Citro, Daniela Antenucci, Lucia Ricci, Francesco Giorgino, Costanza Santini, Agostino Gnasso, Salvatore De Cosmo, Donatella Zavaroni, Monica Vedovato, Agostino Consoli, Maria Calabrese, Paolo di Bartolo, Paolo Fornengo, Gabriele Riccardi, Olga Vaccaro, Maria Masulli, Antonio Nicolucci, Aldo Pietro Maggioni, Giorgio Sesti, Paolo Mocarelli, Giuseppe Lucisano, Michele Sacco, Stefano Signorini, Fabrizio Cappellini, Gabriele Riccardi, Massimo Boemi, Federica D'Angelo, Roberto Giansanti, Laura Tanase, Luigi Lanari, Ivano Testa, Lucia Ricci, Francesca Pancani, Anna Ranchelli, Paolo Vagheggi, Alessia Scatona, Lucia Fontana, Francesco Giorgino, Luigi Laviola, Lucia Tarantino, Claudia Ippolito, Vittoria Gigantelli, Mariangela Manicone, Eleonora Conte, Roberto Trevisan, Cristiana Scaranna, Rossella Rota, Anna Corsi, Alessandro R. Dodesini, Giulio Marchesini Reggiani, Luca Montesi, Natalia Mazzella, Gabriele Forlani, Chiara Caselli, Raffaella Di Luzio, Arianna Mazzotti, Antimo Aiello, Angelina Barrea, Antonio Musto, Fiorentina D'Amico, Sebastiano Squatrito, Tiziana Sinagra, Sara Longhitano, Vanessa Trowpea, Maria Sparti, Salvatore Italia, Enrico Lisi, Giuseppe Grasso, Vincenzo Pezzino, Federica Insalaco, Agostino Gnasso, Claudio Carallo, Caterina Scicchitano, Maria Serena De Franceschi, Costanza Santini, Arianna Mazzotti, Chiara Caselli, Giovanni Calbucci, Raffaella Ripani, Laura Corsi, Giacomo Cuneo, Simona Corsi, Carlo B. Giorda, Francesco Romeo, Annalisa Lesina, Marco Comoglio, Caterina Bonetto, Anna Robusto, Elisa Nada, Vincenzo Asprino, Rosa Cetraro, Michelina Impieri, Giuseppe Lucchese, Giovanna Donnarumma, Biagio Tizio, Gennaro Clemente, Lazzaro Lenza, Pia Paraggio, Franco Tomasi, Chiara Zamboni, Nicoletta Dozio, Egle Scalambra, Edoardo Mannucci, Caterina Lamanna, Mauro Cignarelli, Olga La Macchia, Stefania Fariello, Maria Rosaria Sorrentino, Ivano Franzetti, Raffaella Radin, Renzo Cordera, Francesca Annunziata, Laura Affinito Bonabello, Arianna Durante, Mara Dolcino, Fiorenza Gallo, Chiara Mazzucchelli, Anna Aleo, Pierluigi Melga, Lucia Briatore, Davide Maggi, Daniela Storace, Francesca Cecoli, Daniela Antenucci, Ercole D'Ugo, Mario Pupillo, Maria Pompea Antonia Baldassarre, Filippo Salvati, Anita Minnucci, Angelo De Luca, Antonella Zugaro, Livia Santarelli, Angela Bosco, Vittorio Petrella, Grazia Giovanna La Verghetta, Rossella Iannarelli, Antonella De Gregorio, Settimio D'Andrea, Anna Elisa Giuliani, w Lorella Polidoro, Alessandra Sperandio, Filomena Sciarretta, Alfonso Pezzella, Raffaella Buzzetti, Angela Carlone, Stella Potenziani, Chiara Venditti, Chiara Foffi, Salvatore Carbone, Laura Cipolloni, Chiara Moretti, Gaetano Leto, Rosalia Serra, Francesca Petrachi, Isabella Romano, Graziano Di Cianni, Emilia Lacaria, Laura Russo, Chiara Goretti, Claudia Sannino, Giovanna Gregori, Maria Dolci, Laura Bruselli, Mary L. Mori, Fabio Baccetti, Maria Del Freo, Lucia Fontana, Antonino Di Benedetto, Domenico Cucinotta, Loretta Giunta, Maria Concetta Ruffo, Desiree Cannizzaro, Basilio Pintaudi, Giovanni Perrone, Pietro Pata, Francesco Ragonese, Gabriele Lettina, Teresa Mancuso, Aldo Coppolino, Pier Marco Piatti, Lucilla Monti, Michela Stuccillo, Pietro Lucotti, Manuela Setola, Giulia Valentina Crippa, Cinzia Loi, Matteo Oldani, Maria Luisa Bottalico, Beatrice Pellegata, Matteo Bonomo, Laura Silvia Maria Menicatti, Veronica Resi, Federico Bertuzzi, Eugenia Olga Disoteo, Gianluigi Pizzi, Angela Albarosa Rivellese, Giovanni Annuzzi, Brunella Capaldo, Rossella Nappo, Stefania Michela Auciello, Anna Amelia Turco, Lucia Costagliola, Ciro Iovine, Giuseppina Della Corte, Pasquale Vallefuoco, Francesca Nappi, Marilena Vitale, Sara Cocozza, Ornella Ciano, Elena Massimino, Nadia Garofalo, Angelo Avogaro, Monica Vedovato, Gabriella Guarneri, Annunziata Lapolla, Domenico Fedele, Giovanni Sartore, Nino Cristiano Chilelli, Silvia Burlina, Barbara Bonsembiante, Carla Giordano, Aldo Galluzzo, Vittoria Torregrossa, Elisabetta Dall'Aglio, Giovanni Mancastroppa, Leone Arsenio, Federico Cioni, Silvana Caronna, Matteo Papi, Massimiliano Babini, Gabriele Perriello, Fausto Santeusanio, Gioia Calagreti, Alessia Timi, Alice Tantucci, Cecilia Marino, Agostino Consoli, Federica Ginestra, Rosamaria Di Biagio, Merilda Taraborelli, Stefano Del Prato, Roberto Miccoli, Cristina Bianchi, Monia Garofolo, Konstantina Savina Politi, Giuseppe Penno, Donatella Zavaroni, Stefania Livraga, Fabio Calzoni, Giovanni Luigi Francesco Mancastroppa, Roberto Anichini, Elisa Corsini, Anna Tedeschi, Maria Sole Gaglianò, Giulio Ippolito, Elisabetta Salutini, Giuseppe Citro, Francesco Cervellino, Maria Natale, Vita Salvatore, Armando Zampino, Rosa Sinisi, Maria Calabrese, Adolfo Arcangeli, Alessia Zogheri, Sandra Guizzotti, Rossella Longo, Paolo Di Bartolo, Chiara Caselli, Francesca Pellicano, Patrizia Scolozzi, Simona Termine, Alessandra Luberto, Giorgio Ballardini, Anna Carla Babini, Raffaella Ripani, Cristina Trojani, Paolo Mazzuca, Matteo Bruglia, Monica Ciamei, Silvia Genghini, Chiara Zannoni, Giuseppe Pugliese, Martina Vitale, Graziela Rangel, Laura Salvi, Alessandra Zappaterreno, Samantha Cordone, Paola Simonelli, Marilla Meggiorini, Aurora Frasheri, Clelia Di Pippo, Cristina Maglio, Giulia Mazzitelli, Davide Lauro, Maria Elena Rinaldi, Angelica Galli, Maria Romano, Paola D'Angelo, Sergio Leotta, Concetta Suraci, Salvatore De Cosmo, Simonetta Bacci, Antonio Pio Palena, Stefano Genovese, Monica Mancino, Maurizio Rondinelli, Filippo Capone, Elisabetta Calabretto, Monica Bulgheroni, Loredana Bucciarelli, Francesco Dotta, Elena Ceccarelli, Cecilia Fondelli, Clorinda Santacroce, Elisa Guarino, Laura Nigi, Carlo Lalli, Giovanni Di Vizia, Maura Scarponi, Valeria Montani, Paolo Di Bernardino, Paola Romagni, Katia Dolcetti, Emanuela Cannarsa, Elisa Forte, Stella Potenziani, Lucilla Tamburo, Paolo Fornengo, Paolo Cavallo Perin, Tania Prinzis, Gabriella Gruden, Graziella Bruno, Chiara Zucco, Massimo Perotta, Saverio Marena, Simona Monsignore, Francesco Panero, Fulvia Ponzi, Antonio Carlo Bossi, Rita Carpinteri, Maria Linda Casagrande, Maria Francesca Coletti, Laura Silvia Maria Menicatti, Annalisa Balini, Marcello Filopanti, Sara Madaschi, Anna Pulcina, Franco Grimaldi, Laura Tonutti, Giorgio Venturini, Sandra Agus, Stefania Pagnutti, Francesca Guidotti, Alessandro Cavarape, Maria Linda Casagrande, Enzo Bonora, Massimo Cigolini, Isabella Pichiri, Corinna Brangani, Giulia Fainelli, Elena Tomasetto, Giacomo Zoppini, Anna Galletti, Dominica Perrone, Claudio Capra, Francesca Bianchini, Martina Ceseri, Barbara Di Nardo, Elisa Sasso, Barbara Bartolomei, Irina Suliman, Gianna Fabbri
    更新日期:2017-09-13
  • Pioglitazone versus sulfonylureas: cardiovascular outcomes with older diabetes drugs
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-13
    Vivian A Fonseca, Dragana Lovre

    With a plethora of new drugs for diabetes, and distinct differences in their mechanisms of action and non-glycaemic effects, the selection of a second-line medication to add to metformin is now a complex decision. Guidelines1,2 offer some suggestions for individualisation of treatment, based on efficacy, side-effects, and cost. But the appropriate choice might be challenging for clinicians, patients, and payers, and older (and cheaper) drugs such as sulfonylureas and thiazolidinediones remain in use despite concerns about side-effects.

    更新日期:2017-09-13
  • South Asian floods and Hurricane Harvey: diabetes in crisis
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-06
    The Lancet Diabetes & Endocrinology
    更新日期:2017-09-07
  • Distal technologies and type 1 diabetes management
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-31
    Danny C Duke, Samantha Barry, David V Wagner, Jane Speight, Pratik Choudhary, Michael A Harris

    Type 1 diabetes requires intensive self-management to avoid acute and long-term health complications. In the past two decades, substantial advances in technology have enabled more effective and convenient self-management of type 1 diabetes. Although proximal technologies (eg, insulin pumps, continuous glucose monitors, closed-loop and artificial pancreas systems) have been the subject of frequent systematic and narrative reviews, distal technologies have received scant attention. Distal technologies refer to electronic systems designed to provide a service remotely and include heterogeneous systems such as telehealth, mobile health applications, game-based support, social platforms, and patient portals. In this Review, we summarise the empirical literature to provide current information about the effectiveness of available distal technologies to improve type 1 diabetes management. We also discuss privacy, ethics, and regulatory considerations, issues of global adoption, knowledge gaps in distal technology, and recommendations for future directions.

    更新日期:2017-09-04
  • Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-29
    Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan, Matthew McQueen, Gilles Dagenais, Andreas Wielgosz, Scott Lear, Wei Li, Hui Chen, Sun Yi, Yang Wang, Rafael Diaz, Alvaro Avezum, Patricio Lopez-Jaramillo, Pamela Seron, Rajesh Kumar, Rajeev Gupta, Viswanathan Mohan, Sumathi Swaminathan, Raman Kutty, Katarzyna Zatonska, Romaina Iqbal, Rita Yusuf, Noushin Mohammadifard, Rasha Khatib, Nafiza Mat Nasir, Noorhassim Ismail, Aytekin Oguz, Annika Rosengren, Afzalhussein Yusufali, Edelweiss Wentzel-Viljoen, Thandi Puoane, Jephat Chifamba, Koon Teo, Sonia S Anand, Salim Yusuf, S Yusuf, S Rangarajan, K K Teo, C K Chow, M O'Donnell, A Mente, D Leong, A Smyth, P Joseph, A Merchant, S Islam, M Zhang, W Hu, C Ramasundarahettige, G Wong, S Bangdiwala, L Dyal, A Casanova, M Dehghan, G Lewis, A Aliberti, A Arshad, A Reyes, A Zaki, B Lewis, B Zhang, D Agapay, D Hari, E Milazzo, E Ramezani, F Hussain, F Shifaly, G McAlpine, I Kay, J Lindeman, J Rimac, J Swallow, L Heldman, M(a) Mushtaha, M(o) Mushtaha, M Trottier, M Riggi, N Aoucheva, N Kandy, P Mackie, R Solano, S Chin, S Ramacham, S Shahrook, S Trottier, T Tongana, W ElSheikh, Y Iyengar, M McQueen, K Hall, J Keys, X Wang, J Keneth, A Devanath, R Diaz, A Orlandini, B Linetsky, S Toscanelli, G Casaccia, JM Maini Cuneo, O Rahman, R Yusuf, AK Azad, KA Rabbani, HM Cherry, A Mannan, I Hassan, AT Talukdar, RB Tooheen, MU Khan, M Sintaha, T Choudhury, R Haque, S Parvin, A Avezum, GB Oliveira, CS Marcilio, AC Mattos, K Teo, S Yusuf, J Dejesus, D Agapay, T Tongana, R Solano, I Kay, S Trottier, J Rimac, W Elsheikh, L Heldman, E Ramezani, G Dagenais, P Poirier, G Turbide, D Auger, A LeBlanc De Bluts, MC Proulx, M Cayer, N Bonneville, S Lear, D Gasevic, E Corber, V de Jong, I Vukmirovich, A Wielgosz, G Fodor, A Pipe, A Shane, F Lanas, P Seron, S Martinez, A Valdebenito, M Oliveros, Li Wei, Liu Lisheng, Chen Chunming, Wang Xingyu, Zhao Wenhua, Zhang Hongye, Jia Xuan, Hu Bo, Sun Yi, Bo Jian, Zhao Xiuwen, Chang Xiaohong, Chen Tao, Chen Hui, Chang Xiaohong, Deng Qing, Cheng Xiaoru, Deng Qing, He Xinye, Hu Bo, Jia Xuan, Li Jian, Li Juan, Liu Xu, Ren Bing, Sun Yi, Wang Wei, Wang Yang, Yang Jun, Zhai Yi, Zhang Hongye, Zhao Xiuwen, Zhu Manlu, Lu Fanghong, Wu Jianfang, Li Yindong, Hou Yan, Zhang Liangqing, Guo Baoxia, Liao Xiaoyang, Zhang Shiying, Bian Rongwen, Tian Xiuzhen, Li Dong, Chen Di, Wu Jianguo, Xiao Yize, Liu Tianlu, Zhang Peng, Dong Changlin, Li Ning, Ma Xiaolan, Yang Yuqing, Lei Rensheng, Fu Minfan, He Jing, Liu Yu, Xing Xiaojie, Zhou Qiang, P Lopez-Jaramillo, PA Camacho Lopez, R Garcia, LJA Jurado, D Gómez-Arbeláez, JF Arguello, R Dueñas, S Silva, LP Pradilla, F Ramirez, DI Molina, C Cure-Cure, M Perez, E Hernandez, E Arcos, S Fernandez, C Narvaez, J Paez, A Sotomayor, H Garcia, G Sanchez, T David, A Rico, P Mony, M Vaz, A V Bharathi, S Swaminathan, K Shankar AV Kurpad, KG Jayachitra, N Kumar, HAL Hospital, V Mohan, M Deepa, K Parthiban, M Anitha, S Hemavathy, T Rahulashankiruthiyayan, D Anitha, K Sridevi, R Gupta, RB Panwar, I Mohan, P Rastogi, S Rastogi, R Bhargava, R Kumar, J S Thakur, B Patro, PVM Lakshmi, R Mahajan, P Chaudary, V Raman Kutty, K Vijayakumar, K Ajayan, G Rajasree, AR Renjini, A Deepu, B Sandhya, S Asha, HS Soumya, R Kelishadi, A Bahonar, N Mohammadifard, H Heidari, K Yusoff, TST Ismail, KK Ng, A Devi, NM Nasir, MM Yasin, M Miskan, EA Rahman, MKM Arsad, F Ariffin, SA Razak, FA Majid, NA Bakar, MY Yacob, N Zainon, R Salleh, MKA Ramli, NA Halim, SR Norlizan, NM Ghazali, MN Arshad, R Razali, S Ali, HR Othman, CWJCW Hafar, A Pit, N Danuri, F Basir, SNA Zahari, H Abdullah, MA Arippin, NA Zakaria, I Noorhassim, MJ Hasni, MT Azmi, MI Zaleha, KY Hazdi, AR Rizam, W Sazman, A Azman, R Khatib, U Khammash, A Khatib, R Giacaman, R Iqbal, A Afridi, R Khawaja, A Raza, K Kazmi, A Dans, HU Co, JT Sanchez, L Pudol, C Zamora-Pudol, LAM Palileo-Villanueva, MR Aquino, C Abaquin, SL Pudol, ML Cabral, W Zatonski, A Szuba, K Zatonska, R Ilow, M Ferus, B Regulska-Ilow, D Rózanska, M Wolyniec, KF AlHabib, A Hersi, T Kashour, H Alfaleh, M Alshamiri, HB Altaradi, O Alnobani, A Bafart, N Alkamel, M Ali, M Abdulrahman, R Nouri, A Kruger, H H Voster, A E Schutte, E Wentzel-Viljoen, FC Eloff, H de Ridder, H Moss, J Potgieter, AA Roux, M Watson, G de Wet, A Olckers, JC Jerling, M Pieters, T Hoekstra, T Puoane, E Igumbor, L Tsolekile, D Sanders, P Naidoo, N Steyn, N Peer, B Mayosi, B Rayner, V Lambert, N Levitt, T Kolbe-Alexander, L Ntyintyane, G Hughes, R Swart, J Fourie, M Muzigaba, S Xapa, N Gobile, K Ndayi, B Jwili, K Ndibaza, B Egbujie, A Rosengren, K Bengtsson Boström, A Gustavsson, M Andreasson, M Snällman, L Wirdemann, K Yeates, J Sleeth, K Kilonzo, A Oguz, N Imeryuz, Y Altuntas, S Gulec, A Temizhan, K Karsidag, KBT Calik, AAK Akalin, OT Caklili, MV Keskinler, AN Erbakan, AM Yusufali, W Almahmeed, H Swidan, EA Darwish, ARA Hashemi, N Al-Khaja, JM Muscat-Baron, SH Ahmed, TM Mamdouh, WM Darwish, MHS Abdelmotagali, SA Omer Awed, GA Movahedi, F Hussain, H Al Shaibani, RIM Gharabou, DF Youssef, AZS Nawati, ZAR Abu Salah, RFE Abdalla, SM Al Shuwaihi, MA Al Omairi, OD Cadigal, R.S. Alejandrino, J Chifamba, L Gwaunza, G Terera, C Mahachi, P Murambiwa, T Machiweni, R Mapanga
    更新日期:2017-08-29
  • Macronutrients and cardiovascular risk in a global context
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-29
    Nita G Forouhi, Naveed Sattar, Fumiaki Imamura
    更新日期:2017-08-29
  • Type 2 diabetes in adolescents and young adults
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-25
    Nadia Lascar, James Brown, Helen Pattison, Anthony H Barnett, Clifford J Bailey, Srikanth Bellary
    更新日期:2017-08-26
  • Aiding sleep in type 2 diabetes: therapeutic considerations
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-24
    Xiao Tan, Lieve van Egmond, Colin D Chapman, Jonathan Cedernaes, Christian Benedict
    更新日期:2017-08-25
  • Meta-analysis of artificial pancreas trials: methodological considerations – Authors' reply
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-01
    Alanna Weisman, Caroline K Kramer, Bruce A Perkins

    We thank Eleni Bekiari and colleagues for highlighting these important methodological issues.

    更新日期:2017-08-23
  • Meta-analysis of artificial pancreas trials: methodological considerations
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-01
    Eleni Bekiari, Thomas Karagiannis, Anna-Bettina Haidich, Apostolos Tsapas

    In their systematic review and meta-analysis,1 Alanna Weisman and colleagues review the evidence base of randomised controlled trials comparing artificial pancreas systems with conventional or sensor-augmented pump therapy.

    更新日期:2017-08-23
  • Issues with European guidelines for phenylketonuria – Authors' reply
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-01
    Francjan J van Spronsen, Annemiek M J van Wegberg, Kirsten Ahring, Amaya Bélanger-Quintana, Nenad Blau, Annet M Bosch, Alberto Burlina, Jaime Campistol, Francois Feillet, Maria Giżewska, Stephan C Huijbregts, Shauna Kearney, Vincenzo Leuzzi, Francois Maillot, Ania C Muntau, Fritz K Trefz, Margreet van Rijn, Anita MacDonald

    Peter Burgard and colleagues argue that two key statements from our key European guidelines on phenylketonuria1 are too contentious.

    更新日期:2017-08-23
  • Issues with European guidelines for phenylketonuria
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-01
    Peter Burgard, Kurt Ullrich, Diana Ballhausen, Julia B Hennermann, Carla E M Hollak, Mirjam Langeveld, Daniela Karall, Vassiliki Konstantopoulou, Esther M Maier, Frauke Lang, Robin Lachmann, Elaine Murphy, Sven Garbade, Georg F Hoffmann, Stefan Kölker, Martin Lindner, Johannes Zschocke

    Newborn screening and early dietary treatment for phenylketonuria is a major medical success story. More people are screened for phenylketonuria than for any other inherited condition. Since 1970, the outlook for affected individuals has been transformed from severe intellectual disability to fully normal personal, professional, and social lives. Like in many other rare diseases, high quality studies of treatment and outcomes in phenylketonuria are scarce. This scarcity is reflected in the recent key European guidelines for the diagnosis and management of phenylketonuria published in The Lancet Diabetes & Endocrinology.

    更新日期:2017-08-23
  • A UK Civil Aviation Authority protocol to allow pilots with insulin-treated diabetes to fly commercial aircraft
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-09-01
    Stuart J Mitchell, Julia Hine, Jill Vening, Joanne Montague, Sally Evans, Ken M Shaw, Brian M Frier, Simon R Heller, David L Russell-Jones
    更新日期:2017-08-23
  • Research misconduct and the INTERGROWTH-21st study
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-22
    Lawrence D Platt, Torvid Kiserud, Marshall Lindheimer

    We respectfully take issue with the Comment published in February, 2017, by members of The Lancet's editorial staff stating that WHO's judgment of misconduct regarding the Oxford INTERGROWTH-21st study was unproven.1–3 We are saddened by the fact that they base their conclusion on limited and biased material and simply dismiss the case as rivalry. As members of the WHO Fetal Growth research group and a former WHO external expert not associated with that trial but with evidence that WHO initially refused to hear, we wish to note the following.

    更新日期:2017-08-23
  • Risk of atrial fibrillation in people with type 1 diabetes compared with matched controls from the general population: a prospective case-control study
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-21
    Sofia Dahlqvist, Annika Rosengren, Soffia Gudbjörnsdottir, Aldina Pivodic, Hans Wedel, Mikhail Kosiborod, Ann-Marie Svensson, Marcus Lind
    更新日期:2017-08-22
  • Is atrial fibrillation another manifestation of organ damage in diabetes?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-21
    Kazuo Miyazawa, Gregory Y H Lip
    更新日期:2017-08-22
  • Non-surgical treatment of diabetic foot osteomyelitis
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-01-17
    Mesut Mutluoglu, Benjamin A Lipsky
    更新日期:2017-08-10
  • Diabetes in sub-Saharan Africa: from clinical care to health policy
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-07-05
    Rifat Atun, Justine I Davies, Edwin A M Gale, Till Bärnighausen, David Beran, Andre Pascal Kengne, Naomi S Levitt, Florence W Mangugu, Moffat J Nyirenda, Graham D Ogle, Kaushik Ramaiya, Nelson K Sewankambo, Eugene Sobngwi, Solomon Tesfaye, John S Yudkin, Sanjay Basu, Christian Bommer, Esther Heesemann, Jennifer Manne-Goehler, Iryna Postolovska, Vera Sagalova, Sebastian Vollmer, Zulfiqarali G Abbas, Benjamin Ammon, Mulugeta Terekegn Angamo, Akhila Annamreddi, Ananya Awasthi, Stéphane Besançon, Sudhamayi Bhadriraju, Agnes Binagwaho, Philip I Burgess, Matthew J Burton, Jeanne Chai, Felix P Chilunga, Portia Chipendo, Anna Conn, Dipesalema R Joel, Arielle W Eagan, Crispin Gishoma, Julius Ho, Simcha Jong, Sujay S Kakarmath, Yasmin Khan, Ramu Kharel, Michael A Kyle, Seitetz C Lee, Amos Lichtman, Carl P Malm, Maïmouna N Mbaye, Marie A Muhimpundu, Beatrice M Mwagomba, Kibachio Joseph Mwangi, Mohit Nair, Simon P Niyonsenga, Benson Njuguna, Obiageli L O Okafor, Oluwakemi Okunade, Paul H Park, Sonak D Pastakia, Chelsea Pekny, Ahmed Reja, Charles N Rotimi, Samuel Rwunganira, David Sando, Gabriela Sarriera, Anshuman Sharma, Assa Sidibe, Elias S Siraj, Azhra S Syed, Kristien Van Acker, Mahmoud Werfalli
    更新日期:2017-08-10
  • Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-27
    David Z I Cherney, Bernard Zinman, Silvio E Inzucchi, Audrey Koitka-Weber, Michaela Mattheus, Maximilian von Eynatten, Christoph Wanner
    更新日期:2017-08-10
  • Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-11
    John R Petrie, Nishi Chaturvedi, Ian Ford, Martijn C G J Brouwers, Nicola Greenlaw, Therese Tillin, Irene Hramiak, Alun D Hughes, Alicia J Jenkins, Barbara E K Klein, Ronald Klein, Teik C Ooi, Peter Rossing, Coen D A Stehouwer, Naveed Sattar, Helen M Colhoun, H Nickerson, O Lou, S Dutta, J Haw, C Anderson, S Kean, E Thomson, L Gillespie, J Gibb, N Greenlaw, A Keech, A Jenkins, K March, S Williams, E Coady, M Bots, J Dreyer, T Jan, K Sheffy, R Lusky, S Peleg, A Shore, D Carty, P Donnan, M Witham, A Adler, E Lonn, P Rauchhaus, R Lindsay, M Brouwers, J Van-Melckebeke, L Gillespie, T Hamill, L Cuthbertson, A Murray, L Jolly, E Miller, J Hair, A Bell, S Carmichael, E Douglas, P Surtees, E Dinnett, J Allan, C Watson, M McLaughlin, G Brindley, E Smillie, D Motherwell, S MacDonald, P Ellis, D Stuart, M Travers, S Brearley, L Greig, P Colman, A Nankervis, S Forulanos, D West, S Vaughan, M Bjorasen, J Donlan, J Vrazas, D O'Neal, J Horsburgh, H Pater, S Kent, S Twigg, G Fulcher, R Denner, A Piotrowicz, A Januszewski, A Coy, T Paul, C McDonald, S Tereschyn, N Schmidt, M Weingert, H Heard, S Burke, TC Ooi, H Lochnan, A Sorisky, E Keely, J Malcolm, J Maranger, C Favreau, S Petherick, K Boles, P Rossing, TW Hansen, S Lund, B Hemmingsen, N Thorogood, K Green, T Robinson, K Abouglilia, D Nayman, C Miller, R Warren, K Aizawa, M Balasubramani, S Toth, K Harvey, G Birch, S Atkin, T Sathyapalan, A James, Z Javed, J Wilding, B Martin, S Birch, A Wilcox, N Watson, N Oliver, N Jugnee, M Rutter, T Turgut, A Shaju, S Yau, S Subin, M Walker, D Wake, C Miller, A Millward, P Chong, M Hibbert, J George, N Schaper, J Pinxt, J op het Roodt, S Phillips, L Murray, L Sleigh, A Collier, LE Sit, K Allan, J Cook, K Campbell, L Hodge, G Leese, G Reekie, A Jaap, A Sudworth, A White
    更新日期:2017-08-10
  • Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR–INDIAB population-based cross-sectional study
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-07
    Ranjit Mohan Anjana, Mohan Deepa, Rajendra Pradeepa, Jagadish Mahanta, Kanwar Narain, Hiranya Kumar Das, Prabha Adhikari, Paturi Vishnupriya Rao, Banshi Saboo, Ajay Kumar, Anil Bhansali, Mary John, Rosang Luaia, Taranga Reang, Somorjit Ningombam, Lobsang Jampa, Richard O Budnah, Nirmal Elangovan, Radhakrishnan Subashini, Ulagamathesan Venkatesan, Ranjit Unnikrishnan, Ashok Kumar Das, Sri Venkata Madhu, Mohammed K Ali, Arvind Pandey, Rupinder Singh Dhaliwal, Tanvir Kaur, Soumya Swaminathan, Viswanathan Mohan, Ranjit Mohan Anjana, Mohan Deepa, Rajendra Pradeepa, Jagadish Mahanta, Kanwar Narain, Hiranya Kumar Das, Prabha Adhikari, Paturi Vishnupriya Rao, Banshi Saboo, Ajay Kumar, Anil Bhansali, Mary John, Rosang Luaia, Taranga Reang, Somorjit Ningombam, Lobsang Jampa, Richard O Budnah, Nirmal Elangovan, Radhakrishnan Subashini, Ulagamathesan Venkatesan, Ranjit Unnikrishnan, Ashok Kumar Das, Sri Venkata Madhu, Mohammed K Ali, Arvind Pandey, R S Dhaliwal, Tanvir Kaur, Soumya Swaminathan, Viswanathan Mohan, Vasudevan Sudha, Somasundaram Jaya Parvathi, Ramamoorthy Jayashri, Kaliaperumal Velmurugan, Prasanta Kumar Borah, Sathish B Rao, Jayendrasinh M. Padhiyar, Smita Sharma, Pachuau Lalramenga, Swapan Kumar Das, Th Bhubhonchandra Singh, Tao Kaki, Manoj Risbud Basaiawmoit, Deepak Kumar Shukla, Modugu Nageswara Rao, Prashant P Joshi, Vinay Kumar Dhandania, Shashank R Joshi, Chittaranjan Sakerlal Yajnik
    更新日期:2017-08-10
  • Absorbing metabolic illness in India
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    Emily Yates-Doerr
    更新日期:2017-08-10
  • Endocrinology through the ages
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-03-31
    Sophie Watt
    更新日期:2017-08-10
  • Michèle Ramsay: working collaboratively to improve African health
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2016-09-13
    Fiona Mitchell
    更新日期:2017-08-10
  • Oldest case of gigantism? Assessment of the alleged remains of Sa-Nakht, king of ancient Egypt
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    Francesco M Galassi, Maciej Henneberg, Wouter de Herder, Frank Rühli, Michael E Habicht
    更新日期:2017-08-10
  • Microvascular outcomes in type 2 diabetes – Authors' reply
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    Sophia Zoungas, Hertzel C Gerstein, Rury R Holman, Peter Reaven, Mark Woodward, Hisatomi Arima, Ruth L Coleman, John Chalmers

    We appreciate Coen Stehouwer and Thomas van Sloten's comments on the clinical relevance of the endpoints in our meta-analysis of individual participant data from the four large trials of more versus less intensive glucose control in patients with type 2 diabetes. The selection of endpoints followed a rigorous, prespecified process that included foremost: consideration of clinical relevance, use of common definitions, standardised ascertainment, and data availability across the trials.

    更新日期:2017-08-10
  • Microvascular outcomes in type 2 diabetes
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    Coen D A Stehouwer, Thomas T van Sloten

    In the individual participant data meta-analysis by Zoungas and colleagues,1 more compared with less intensive glucose control reduced the risk of kidney and eye events, but not nerve events. However, we are concerned that not all endpoints used are of direct relevance for the clinic.

    更新日期:2017-08-10
  • Hyperglycaemia in pregnancy: time to ask the hard questions?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    Uma Ram, Suresh Seshadri, Ponnusamy Saravanan

    We read the Comment by Arianne Sweeting and colleagues with great interest.1 The researchers highlighted the Cambridge data, which suggest that accelerated foetal growth might occur between 20 and 28 weeks of gestation, before the diagnosis of gestational diabetes. These data suggested no differences in abdominal or head circumferences at 20 weeks. Our recent study2 of babies in South India showed that foetal subcutaneous abdominal adiposity is already higher at 20 weeks of gestation in women who later developed gestational diabetes (4·7 weeks later) compared with those who did not.

    更新日期:2017-08-10
  • The role of biosimilar manufacturers in improving access to insulin globally
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-16
    Christophe Perrin, Margaret Ewen, David Beran

    The production and use of generic medicines has substantially improved access to medicines in low-income and middle-income countries.1 For HIV/AIDS, the production of generic antiretrovirals (ARVs) resulted in prices falling from US$10 439 per patient per year (produced by the originator) to US$132 (generic producer) between 2000 and 2006.2 Although first used in 1922, access to insulin remains problematic to this day.3 Unlike ARVs or most other medicines, insulin is a biological product and thus creating an exact copy (biosimilar) is more difficult than creating a copy of a chemical entity.

    更新日期:2017-08-10
  • Diabetes in sub-Saharan Africa: let us not forget type 1
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-07-05
    Silver K Bahendeka

    In the past two decades, the global health landscape has undergone rapid transformation, from communicable diseases being the leading causes of disability and death to non-communicable diseases taking the lead. People around the world are living longer than ever before, and the population is getting older. However, the observed trends in the global health landscape have varied substantially across regions and countries, with sub-Saharan Africa being a striking example. Communicable, maternal, nutritional, and newborn diseases have continued to dominate in sub-Saharan Africa alongside the increasing prevalence of type 2 diabetes, hypertension, cardiovascular and respiratory diseases, and cancer.

    更新日期:2017-08-10
  • The crisis of diabetes in sub-Saharan Africa
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-07-05
    Shabbar Jaffar, Geoffrey Gill
    更新日期:2017-08-10
  • Gestational diabetes in the first trimester: is early testing justified?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-02-28
    Arianne N Sweeting, Glynis P Ross, Jon Hyett, Jencia Wong

    Most studies demonstrating the risks of gestational diabetes1 and the benefits of treatment2 are limited to women diagnosed at 24 weeks' gestation and later. Such data have provided the rationale for universal testing for gestational diabetes from 24 weeks' gestation and the revised diagnostic criteria proposed by the International Association of Diabetes and Pregnancy Study Groups (IADPSG)3 and endorsed by WHO4 (diagnosis based on one or more of the following: fasting plasma glucose 5·1–6·9 mmol/L, 1 h post-load glucose ≥10·0 mmol/L, 2 h post-load glucose 8·5–11·0 mmol/L following a 2 h 75 g oral glucose tolerance test).

    更新日期:2017-08-10
  • SGLT2 inhibition: a new era in renoprotective medicine?
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-27
    Marcel H A Muskiet, Hiddo J L Heerspink, Daniël H van Raalte
    更新日期:2017-08-10
  • Metformin in type 1 diabetes
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-11
    Eberhard Standl

    In The Lancet Diabetes & Endocrinology, John Petrie and colleagues report the main outcome results of the REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL) study,1 a well designed, double-blind, randomised, placebo-controlled trial in 428 adult patients (40 years and older) with type 1 diabetes and multiple cardiovascular risk factors. The aim of REMOVAL was to investigate the effects of metformin (1000 mg twice daily) on intima-media thickening of the common carotid artery (cIMT)—a surrogate measure of atherosclerosis—as well as on metabolic and other outcomes over 3 years.

    更新日期:2017-08-10
  • The need for improved diabetes care in India
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-06-07
    Vijay Viswanathan
    更新日期:2017-08-10
  • Forging paths to improve diabetes care in low-income settings
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-08-01
    The Lancet Diabetes & Endocrinology
    更新日期:2017-08-10
  • Alafia Samuels: fast-food watchdog in the Caribbean
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2016-11-01
    Ray Cavanaugh
    更新日期:2017-08-10
  • Nizar Albache: championing the cause of Syrian refugees with diabetes
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2016-11-24
    Jennifer Thorley
    更新日期:2017-08-10
  • Hyperinsulinaemic hypoglycaemia in children and adults
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2016-11-30
    Pratik Shah, Sofia A Rahman, Huseyin Demirbilek, Maria Güemes, Khalid Hussain
    更新日期:2017-08-10
  • Key European guidelines for the diagnosis and management of patients with phenylketonuria
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-01-09
    Francjan J van Spronsen, Annemiek MJ van Wegberg, Kirsten Ahring, Amaya Bélanger-Quintana, Nenad Blau, Annet M Bosch, Alberto Burlina, Jaime Campistol, Francois Feillet, Maria Giżewska, Stephan C Huijbregts, Shauna Kearney, Vincenzo Leuzzi, Francois Maillot, Ania C Muntau, Fritz K Trefz, Margreet van Rijn, John H Walter, Anita MacDonald
    更新日期:2017-08-10
  • The politics of health inequalities
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-02-22
    Talha Khan Burki
    更新日期:2017-08-10
  • Changing ethical and legal norms in the management of differences of sex development
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-02-22
    Maayan Sudai

    The medical management of people with indefinite sex or differences of sex development (DSD)—some of whom identify as intersex—has gone through substantial transformations in recent years. The modern approach to management of DSD in the USA, Australia, and Europe was conceived in the 1950s at Johns Hopkins Hospital (Baltimore, MD, USA) through a collaboration of leading physicians from various disciplines, including paediatrics, urology, plastic surgery, psychiatry, and psychology. Their work led to the development of present treatment protocols issued by professional societies.

    更新日期:2017-08-10
  • Obesity stories
    Lancet Diabetes Endocrinol. (IF 19.742) Pub Date : 2017-02-28
    Jules Morgan
    更新日期:2017-08-10
Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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