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  • Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-17
    Lucas E Hermans, Michelle Moorhouse, Sergio Carmona, Diederick E Grobbee, L Marije Hofstra, Douglas D Richman, Hugo A Tempelman, Willem D F Venter, Annemarie M J Wensing
    更新日期:2017-11-19
  • Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-17
    Chunqing Lin, Silvia Franceschi, Gary M Clifford
    更新日期:2017-11-19
  • Stepping up HIV-1 low-level viraemia surveillance in South Africa
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-17
    Antonella Castagna, Laura Galli
    更新日期:2017-11-19
  • The importance of HPV16 in anal cancer prevention
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-17
    Ulrike Wieland, Alexander Kreuter
    更新日期:2017-11-19
  • Tribendimidine: an alternative to praziquantel to treat human liver fluke infection?
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-16
    Banchob Sripa
    更新日期:2017-11-17
  • Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-15
    Alexei Zelenev, Jianghong Li, Alyona Mazhnaya, Sanjay Basu, Frederick L Altice
    更新日期:2017-11-16
  • Ebola virus disease: an update on post-exposure prophylaxis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-15
    William A Fischer, Pauline Vetter, Daniel G Bausch, Timothy Burgess, Richard T Davey, Robert Fowler, Frederick G Hayden, Peter B Jahrling, Andre C Kalil, Douglas L Mayers, Aneesh K Mehta, Timothy M Uyeki, Michael Jacobs

    The massive outbreak of Ebola virus disease in west Africa between 2013 and 2016 resulted in intense efforts to evaluate the efficacy of several specific countermeasures developed through years of preclinical work, including the first clinical trials for therapeutics and vaccines. In this Review, we discuss how the experience and data generated from that outbreak have helped to advance the understanding of the use of these countermeasures for post-exposure prophylaxis against Ebola virus infection. In future outbreaks, post-exposure prophylaxis could play an important part in reducing community transmission of Ebola virus by providing more immediate protection than does immunisation as well as providing additional protection for health-care workers who are inadvertently exposed over the course of their work. We propose provisional guidance for use of post-exposure prophylaxis in Ebola virus disease and identify the priorities for future preparedness and further research.

    更新日期:2017-11-16
  • Advancing political will to end the tuberculosis epidemic
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-15
    Nick Herbert, Baroness Susan Masham, Baroness Alison Suttie, Virendra Sharma, Stephan Albani, Oxana Domenti, Rosanna Flurry, Matthew Oliver, Alimuddin Zumla

    WHO's End TB Strategy1 and the 2015 UN Sustainable Development Goals (SDGs)2 share a common aim of bringing the global tuberculosis epidemic under control by 2035. Achieving the 2015 UN mandate to address the tuberculosis epidemic (SDG3, target 3)2 will also help advance other goals, since tuberculosis is both a driver and a consequence of poverty. A renewed and increased political commitment is required to accelerate progress towards achieving specific tuberculosis control targets. Through the new lens of the SDGs, the End TB Strategy focuses on putting patients and communities at the heart of the global tuberculosis response, aiming to reduce the number of tuberculosis deaths by 90% by 2030.

    更新日期:2017-11-16
  • How to eliminate HCV in people who inject drugs in the USA
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-15
    Harel Dahari, Basmattee Boodram
    更新日期:2017-11-16
  • Zika virus in French Polynesia 2013–14: anatomy of a completed outbreak
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-14
    Didier Musso, Hervé Bossin, Henri Pierre Mallet, Marianne Besnard, Julien Broult, Laure Baudouin, José Eduardo Levi, Ester C Sabino, Frederic Ghawche, Marion C Lanteri, David Baud
    更新日期:2017-11-15
  • Use of mathematical modelling to assess the impact of vaccines on antibiotic resistance
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-13
    Katherine E Atkins, Erin I Lafferty, Sarah R Deeny, Nicholas G Davies, Julie V Robotham, Mark Jit
    更新日期:2017-11-14
  • Addressing antimicrobial resistance in the UK and Europe
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-10
    Victoria Wells, Laura J V Piddock

    Antimicrobial resistance (AMR) has received substantial attention in recent years. Since bacteria evolve to resist the effects of existing antibiotics, infections can become more difficult to treat and subsequently modern medical interventions can become more dangerous for patients. Fear of so-called superbugs has spurred international authorities into action. In 2011, WHO developed a European strategic action plan on antibiotic resistance,1 which set forth strategic objectives to aid European member states in addressing the complex factors that cause AMR.

    更新日期:2017-11-11
  • Achieving safe, effective, and durable Zika virus vaccines: lessons from dengue
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-12
    Scott B Halstead

    Newly proposed candidate Zika virus vaccines might or might not succeed in raising safe, effective, and durable protection against human Zika virus infections or syndromes. Analyses of a clinically tested and licensed dengue vaccine that failed to protect seronegative individuals from breakthrough or enhanced dengue infections suggest that poor T-cell immunity might have contributed to protection failure. Because of the similarity of Zika and dengue viruses, an analogous unwanted outcome might occur with some Zika virus vaccine designs. A successful Zika virus vaccine requires challenge experiments that are done at long intervals after immunisation and that identify protection as the absence of viraemia and the absence of an anamnestic antibody response. T-cell immunity might be an essential component of safe, efficacious, and durable Zika virus vaccines.

    更新日期:2017-11-10
  • Neglected endemic mycoses
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-31
    Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
    更新日期:2017-11-10
  • Pulmonary and sinus fungal diseases in non-immunocompromised patients
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-31
    David W Denning, Arunaloke Chakrabarti
    更新日期:2017-11-10
  • Candida and invasive mould diseases in non-neutropenic critically ill patients and patients with haematological cancer
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-31
    A L Colombo, J N de Almeida Júnior, Monica A Slavin, Sharon C-A Chen, Tania C Sorrell

    Critically ill patients and patients with haematological cancer are HIV-negative populations at high risk of invasive fungal infections. In intensive-care units, candidaemia and intra-abdominal candidiasis predominate, but aspergillosis has emerged as a lethal, under-recognised cause of pneumonia. In patients with haematological malignancies or who have undergone stem-cell transplantations, pulmonary disease due to aspergillus and other mould diseases predominate. In this Series paper, we provide an update on risk assessment, new diagnostic strategies, and therapeutic approaches. New concepts have emerged for use of risk prediction rules and an evidence base now exists for inclusion of biomarkers (eg, galactomannan, 1,3-β-D-glucan, and PCR assays for Aspergillus spp) into early diagnostic and therapeutic strategies. Imaging techniques remain helpful for early diagnosis of pulmonary mould diseases, with PET techniques offering potential improvements in diagnostic specificity and evaluation of clinical response. Echinocandins and triazoles have been validated extensively for prophylaxis, empirical therapy, and targeted therapy, but an increase in intrinsically resistant fungi and emergence of secondary resistance as a result of drug-induced selection pressure are of major concern. Echinocandins remain a major component of treatment of invasive candidiasis and new triazoles are the best alternative for prophylaxis and therapy of invasive aspergillosis.

    更新日期:2017-11-10
  • Fungal infections in HIV/AIDS
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-31
    Andrew H Limper, Antoine Adenis, Thuy Le, Thomas S Harrison
    更新日期:2017-11-10
  • Global yellow fever vaccination coverage from 1970 to 2016: an adjusted retrospective analysis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-16
    Freya M Shearer, Catherine L Moyes, David M Pigott, Oliver J Brady, Fatima Marinho, Aniruddha Deshpande, Joshua Longbottom, Annie J Browne, Moritz U G Kraemer, Kathleen M O'Reilly, Joachim Hombach, Sergio Yactayo, Valdelaine E M de Araújo, Aglaêr A da Nóbrega, Jonathan F Mosser, Jeffrey D Stanaway, Stephen S Lim, Simon I Hay, Nick Golding, Robert C Reiner
    更新日期:2017-11-10
  • Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-21
    Guillaume Joguet, Jean-Michel Mansuy, Giulia Matusali, Safouane Hamdi, Marie Walschaerts, Lynda Pavili, Stefanie Guyomard, Nadia Prisant, Pierre Lamarre, Nathalie Dejucq-Rainsford, Christophe Pasquier, Louis Bujan
    更新日期:2017-11-10
  • A score to predict and stratify risk of tuberculosis in adult contacts of tuberculosis index cases: a prospective derivation and external validation cohort study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-18
    Matthew J Saunders, Tom Wingfield, Marco A Tovar, Matthew R Baldwin, Sumona Datta, Karine Zevallos, Rosario Montoya, Teresa R Valencia, Jon S Friedland, Larry H Moulton, Robert H Gilman, Carlton A Evans
    更新日期:2017-11-10
  • The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-17
    Flavia R Machado, Alexandre Biasi Cavalcanti, Fernando Augusto Bozza, Elaine M Ferreira, Fernanda Sousa Angotti Carrara, Juliana Lubarino Sousa, Noemi Caixeta, Reinaldo Salomao, Derek C Angus, Luciano Cesar Pontes Azevedo, S R Zajac, M V Bley, M V Bley, A Scazufca, P Rosateli, T Reis, A Nogueira Junior, P A Nunes Neto, I L S Filho, H Lima, M Vieira, M Zanchet, I Ferreira, R Miguita, G M Petisco, G A Westphal, J R P Santos, V Damasceno, J T dos Santos, F Fernandes, EP Almeida, M Lemos, M F A Lima, R Camacho, A Ribeiro, M O G Douglas, G A Mattei, E A Junior, P Ferreira, H R M P Rabelo, S P S Pinto, L E Fontes, D Machado, M Guitzel, M Lucio, C N P Conceição, A Barros, D Salgado, V C Veiga, S S O Rojas, V C Veiga, S S O Rojas, KM de Paula, R Hatum, L Fraenkel, W N Viana, A P G Santos, L Rabello, L Tanaka, M Uchoa, M D Moura, H Gneco, M F Buarque, K Monteiro, A P Nassar, E Koterba, M J Teixeira, A L E Falcão, V G S Pinto, J M M Junior, A L Gut, L M Stefano, M Damasceno, M V Lontra, C Cozzani, E B Sobrinho, S G Lage, L Kopel, N C M Youssef, L C Sanches, C P Amendola, C Kmohan, C B Silva, L Schifelbain, E Bellotto, P Viecili, L Azevedo, L Monteiro, S Vieira, A M Abrão, A P Moraes, H Insaurrale, M Gadelha, D Marisa, R N Diniz, E R Romano, S Luzzi, E Rezende, M C Filho, R H F C Martins, F B Carvalho, G C Moreira, J Paula, F Fernandes, F Haag, FS Lucena, R S Machado, W O Filho, L O Cavalcante, H Carvalho Filho, G S Lima, J N Trombka, E C Machado, M P Bainy, C H Ramos, C Hoppe, G D Luckmeyer, C Vogas, M M Thompson, R K Sousa, R Fernandes, E Lourenço, G L Peixoto, A Mocelin, M M L Silva, J S A Neto, C Villela, S L Mendonça, S C Prado, R Goulart, J J L Duarte, H A O Junior, J N Andrade, L F Souza, L Fernandes, M L Neto, S S Fernandes, F Amâncio, J C Versiani, F Pitanga, M B Alcantara, C C Reiff, R Rosenblat, M S Nobrega, M L F S Nobrega, G Costa, N Assunção, E P Almeida, L Neder, R Almeida, J Fuck, R M Souza, A G Ribeiro, A A G Alves, S H C Carvalho, M Arbex, E C Oliveira, F B Carvalho, R S Melo, K Conde, N Q Abreu, C L T Melo, A A Carvalho, M C Filho, R Lannes, H Missaka, A H Furtado, A A Peixoto, I Maia, M P Pincelli, R Camacho, M P Yunes, A N Pessoa, S Figueiredo, F A Botoni, C T Cunha, F A Olson, R Franco, A F Bemfica, M S Nobrega, A D F Junior, E L A Ferreira, O Messeder, R Passos, J A Lira, C A Vilela, S M D Junior, C S Ferreira, O P J A Muller, R Perreira dos Santos, P Rubini, D Monteiro, L E Rodrigues, G F Ruivo, M C Gomes, E Egito, M G Assef, M A M Lima, A F Borges, M Gadelha, S Jezler, C Mendes, P C Gottardo, R Lima, C M F Filho, V P Campagnucci, I Solino, A P Lorca, A P Lorca, G M Rodrigues, K B Gerent, O Barbosa, G T Henriques Filho, E Troncoso, A Ventura, M A Silva, J G Houly, J P M Pimentel, R A Ramos, F Gianini, B Casemiro, E M Pinto, G A Silva, M Sebold, E Vieira, R Ferreira, L A Gomes, W J Lovato, W Dantas, L Ishy, W Dantas, L Ishy, J Moreira, I Gagliardi, L O Goes, L S Vendrame, H P Guimarães, A Gois, F R Machado, M Rodrigues, P C B Vieira, W Bittencourt, E Melnick, M Schneider, L Rezegue, N J M Nogueira, L Azevedo, E P Godinho, B F Mazza, L E Paciencia, S Ferraz, C R A Imamura, J Tavares, J C Santos, E Vale, J Mugait Filho, L A Tannous, P G D João, C T I Geral, D Salgado, A P Matera, M Matsui, E Eberhart Neto, B V Pinheiro, E V Carvalho, H Matos, M Lippi, A L Campos, D C Albuquerque, D Monteiro, D Castiglioni, G S Silva, S Cunha, E Novello, M E B Silva, C Grion, J Festti, C Grion, J Festti, C R A Souza, G C Mecatti, E B Junqueira, R S Dutra, G B Mirachi, D A Mendes, E M F Moura, I F Silva, M G P Mota, T Carneiro, A Celso, A Réa-Neto, M C Oliveira, A Japiassú, P P Castro, H J M Costa, A V Rolim, D Rocha, C Righy, C Righy, V Santos, B Fernandino, A L Pereira, V L D Rego, M M L Silva, L A Melo, L Guilherme, H Chagas Ferro, F J L Silva, H V C J Carrasco, S El-Fakouri, J Alvarez, D de Castro, P M Shiavetto, S R Gallate, E Thomé Filho, S G Veneziano, W O Filho, P Antoniazzi, W H Filho, P Sadala, C Balbino, G Moreno, M S F Dias, R P Lopez, M L Rodrigues, J Terceiro, M F Serpa, L Santos, W O Filho, M M Lippi, S R Zajac, M V Bley, M V Bley, A Scazufca, P Rosateli, T Reis, A Nogueira Junior, P A Nunes Neto, I L S Filho, H Lima, M Vieira, M Zanchet, I Ferreira, R Miguita, G M Petisco, G A Westphal, J R P Santos, V Damasceno, J T dos Santos, F Fernandes, EP Almeida, M Lemos, M F A Lima, R Camacho, A Ribeiro, M O G Douglas, G A Mattei, E A Junior, P Ferreira, H R M P Rabelo, S P S Pinto, L E Fontes, D Machado, M Guitzel, M Lucio, C N P Conceição, A Barros, D Salgado, V C Veiga, S S O Rojas, V C Veiga, S S O Rojas, KM de Paula, R Hatum, L Fraenkel, W N Viana, A P G Santos, L Rabello, L Tanaka, M Uchoa, M D Moura, H Gneco, M F Buarque, K Monteiro, A P Nassar, E Koterba, M J Teixeira, A L E Falcão, V G S Pinto, J M M Junior, A L Gut, L M Stefano, M Damasceno, M V Lontra, C Cozzani, E B Sobrinho, S G Lage, L Kopel, N C M Youssef, L C Sanches, C P Amendola, C Kmohan, C B Silva, L Schifelbain, E Bellotto, P Viecili, L Azevedo, L Monteiro, S Vieira, A M Abrão, A P Moraes, H Insaurrale, M Gadelha, D Marisa, R N Diniz, E R Romano, S Luzzi, E Rezende, M C Filho, R H F C Martins, F B Carvalho, G C Moreira, J Paula, F Fernandes, F Haag, FS Lucena, R S Machado, W O Filho, L O Cavalcante, H Carvalho Filho, G S Lima, J N Trombka, E C Machado, M P Bainy, C H Ramos, C Hoppe, G D Luckmeyer, C Vogas, M M Thompson, R K Sousa, R Fernandes, E Lourenço, G L Peixoto, A Mocelin, M M L Silva, J S A Neto, C Villela, S L Mendonça, S C Prado, R Goulart, J J L Duarte, H A O Junior, J N Andrade, L F Souza, L Fernandes, M L Neto, S S Fernandes, F Amâncio, J C Versiani, F Pitanga, M B Alcantara, C C Reiff, R Rosenblat, M S Nobrega, M L F S Nobrega, G Costa, N Assunção, E P Almeida, L Neder, R Almeida, J Fuck, R M Souza, A G Ribeiro, A A G Alves, S H C Carvalho, M Arbex, E C Oliveira, F B Carvalho, R S Melo, K Conde, N Q Abreu, C L T Melo, A A Carvalho, M C Filho, R Lannes, H Missaka, A H Furtado, A A Peixoto, I Maia, M P Pincelli, R Camacho, M P Yunes, A N Pessoa, S Figueiredo, F A Botoni, C T Cunha, F A Olson, R Franco, A F Bemfica, M S Nobrega, A D F Junior, E L A Ferreira, O Messeder, R Passos, J A Lira, C A Vilela, S M D Junior, C S Ferreira, O P J A Muller, R Perreira dos Santos, P Rubini, D Monteiro, L E Rodrigues, G F Ruivo, M C Gomes, E Egito, M G Assef, M A M Lima, A F Borges, M Gadelha, S Jezler, C Mendes, P C Gottardo, R Lima, C M F Filho, V P Campagnucci, I Solino, A P Lorca, A P Lorca, G M Rodrigues, K B Gerent, O Barbosa, G T Henriques Filho, E Troncoso, A Ventura, M A Silva, J G Houly, J P M Pimentel, R A Ramos, F Gianini, B Casemiro, E M Pinto, G A Silva, M Sebold, E Vieira, R Ferreira, L A Gomes, W J Lovato, W Dantas, L Ishy, W Dantas, L Ishy, J Moreira, I Gagliardi, L O Goes, L S Vendrame, H P Guimarães, A Gois, F R Machado, M Rodrigues, P C B Vieira, W Bittencourt, E Melnick, M Schneider, L Rezegue, N J M Nogueira, L Azevedo, E P Godinho, B F Mazza, L E Paciencia, S Ferraz, C R A Imamura, J Tavares, J C Santos, E Vale, J Mugait Filho, L A Tannous, P G D João, C T I Geral, D Salgado, A P Matera, M Matsui, E Eberhart Neto, B V Pinheiro, E V Carvalho, H Matos, M Lippi, A L Campos, D C Albuquerque, D Monteiro, D Castiglioni, G S Silva, S Cunha, E Novello, M E B Silva, C Grion, J Festti, C Grion, J Festti, C R A Souza, G C Mecatti, E B Junqueira, R S Dutra, G B Mirachi, D A Mendes, E M F Moura, I F Silva, M G P Mota, T Carneiro, A Celso, A Réa-Neto, M C Oliveira, A Japiassú, P P Castro, H J M Costa, A V Rolim, D Rocha, C Righy, C Righy, V Santos, B Fernandino, A L Pereira, V L D Rego, M M L Silva, L A Melo, L Guilherme, H Chagas Ferro, F J L Silva, H V C J Carrasco, S El-Fakouri, J Alvarez, D de Castro, P M Shiavetto, S R Gallate, E Thomé Filho, S G Veneziano, W O Filho, P Antoniazzi, W H Filho, P Sadala, C Balbino, G Moreno, M S F Dias, R P Lopez, M L Rodrigues, J Terceiro, M F Serpa, L Santos, W O Filho, M M Lippi
    更新日期:2017-11-10
  • Understanding threats to polio vaccine commitment among caregivers in high-priority areas of Afghanistan: a polling study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-14
    Gillian K SteelFisher, Robert J Blendon, Sherine Guirguis, William Lodge, Hannah Caporello, Vincent Petit, Michael Coleman, Matthew R Williams, Sardar Mohammad Parwiz, Melissa Corkum, Scott Gardner, Eran N Ben-Porath

    BackgroundEradication of poliovirus from endemic countries relies on vaccination of children with oral polio vaccine (OPV) many times a year until the age of 5 years. We aimed to determine caregivers' commitment to OPV in districts of Afghanistan at high risk for polio transmission and to examine what knowledge, attitudes, or experiences could threaten commitment. MethodsWe designed and analysed a poll using face-to-face interviews among caregivers of children under 5 years of age. The sample was drawn via a stratified multistage cluster design with random route household selection. We calculated the percentage of committed and uncommitted caregivers. All percentages were weighted. We then compared percentages of uncommitted caregivers among those with varying knowledge, attitudes, and experiences, using logistic regression to control for possible demographic confounders. FindingsBetween Dec 19, 2014, and Jan 5, 2015, we interviewed 1980 caregivers, 21% of whom were “uncommitted” to accepting OPV. Multiple measures of knowledge, attitudes, and experiences are associated with lack of commitment. For example, compared with their relevant counterparts, caregivers are more likely to be uncommitted if they did not trust vaccinators “a great deal” (54% vs 9%), if they do not know that polio spreads through contaminated water (41% vs 14%), or if they believe rumours that OPV is not halal (50% vs 21%). InterpretationTo enhance OPV commitment, it might be useful to consider a multifactorial approach that highlights building trust in vaccinators, providing facts about transmission, sharing positive messages to overcome key rumours, and strengthening community support for vaccination. FundingHarvard T H Chan School of Public Health and UNICEF.

    更新日期:2017-11-10
  • Efficacy and safety of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel pamoate, and albendazole plus oxantel pamoate against hookworm and concomitant soil-transmitted helminth infections in Tanzania and Côte d'Ivoire: a randomised, controlled, single-blinded, non-inferiority trial
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-29
    Wendelin Moser, Jean T Coulibaly, Said M Ali, Shaali M Ame, Amour K Amour, Richard B Yapi, Marco Albonico, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser
    更新日期:2017-11-10
  • Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study 2015
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-23
    Christopher Troeger, Mohammad Forouzanfar, Puja C Rao, Ibrahim Khalil, Alexandria Brown, Scott Swartz, Nancy Fullman, Jonathan Mosser, Robert L Thompson, Robert C Reiner, Amanuel Abajobir, Noore Alam, Mulubirhan Assefa Alemayohu, Azmeraw T Amare, Carl Abelardo Antonio, Hamid Asayesh, Euripide Avokpaho, Aleksandra Barac, Muktar A Beshir, Dube Jara Boneya, Michael Brauer, Lalit Dandona, Rakhi Dandona, Joseph R A Fitchett, Tsegaye Tewelde Gebrehiwot, Gessessew Buggsa Hailu, Peter J Hotez, Amir Kasaeian, Tawfik Khoja, Niranjan Kissoon, Luke Knibbs, G Anil Kumar, Rajesh Kumar Rai, Hassan Magdy Abd El Razek, Muktar S K Mohammed, Katie Nielson, Eyal Oren, Abdalla Osman, George Patton, Mostafa Qorbani, Hirbo Shore Roba, Benn Sartorius, Miloje Savic, Mika Shigematsu, Bryan Sykes, Soumya Swaminathan, Roman Topor-Madry, Kingsley Ukwaja, Andrea Werdecker, Naohiro Yonemoto, Maysaa El Sayed Zaki, Stephen S Lim, Mohsen Naghavi, Theo Vos, Simon I Hay, Christopher J L Murray, Ali H Mokdad
    更新日期:2017-11-10
  • Corrections
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-09-13

    Saunders MJ, Wingfield T, Tovar MA, et al. A score to predict and stratify risk of tuberculosis in adult contacts of tuberculosis index cases: a prospective derivation and external validation cohort study. Lancet Infect Dis 2017; 17: 1090–99—The support and grants in the Acknowledgments section should have been assigned as follows: This study was supported by Wellcome Trust awards 057434/Z/99/B (MAT, KZ, RM, TRV, JSF, RHG, and CAE), Z070005/Z/02/Z (MAT, TRV, JSF, RHG, and CAE), 078340/Z/05/Z (MAT, KZ, RM, TRV, JSF, and RHG, CAE), 105788/Z/14/Z (SD, RHG, and CAE), 201251/Z/16/Z (MJS, RHG, and CAE), the Department for International Development Civil Society Challenge Fund (MAT, KZ, RM, TRV, CAE), the Joint Global Health Trials consortium (Medical Research Council, Department for International Development, and Wellcome Trust award MR/K007467/1 [TW, MAT, KZ, RM, TRV, RHG, and CAE]), the Bill & Melinda Gates Foundation (award OPP1118545 [TW, MAT, RM, TRV, and CAE]), Imperial College National Institutes of Health Research Biomedical Research Centre (JAF and CAE), the Foundation for Innovative New Diagnostics (MAT, KZ, TRV, and CAE), the Sir Halley Stewart Trust (CAE), WHO (CAE), the STOP TB partnership's TB REACH initiative funded by the Government of Canada (W5_PER_CDT1_PRISMA [MAT, RM, and CAE]), and Innovation For Health And Development (MJS, TW, and CAE).

    更新日期:2017-11-10
  • Recovery from serious fungal infections should be realisable for everyone
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-07-31
    Juan Luis Rodríguez Tudela, David W Denning

    Fungal infections are neglected by social and political communities. However, they affect more than a billion people, resulting in approximately 11·5 million life-threatening infections and more than 1·5 million deaths annually.1,2 There have been enormous advances in fungal diagnostics and antifungal drug development over the past 20 years, but most of the world's population has not yet benefited from these advances. The Lancet Infectious Diseases Fungal Infections Series brings readers up to date on fungal infections and addresses how fungal infection management can be integrated into health systems in low-income and middle-income countries (LMICs).

    更新日期:2017-11-10
  • Yellow fever vaccination: estimating coverage
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-16
    Annelies Wilder-Smith
    更新日期:2017-11-10
  • Zika virus infection in semen: effect on human reproduction
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-21
    Luisa Barzon, Enrico Lavezzo, Giorgio Palù
    更新日期:2017-11-10
  • Tuberculosis—making predictions, especially about the future
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-18
    Anna M Mandalakas, Frank Cobelens
    更新日期:2017-11-10
  • Spreading the knowledge on the epidemiology of sepsis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-17
    Jorge I F Salluh, Marcio Soares, Mervyn Singer
    更新日期:2017-11-10
  • Understanding commitment to polio vaccination
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-14
    Kathleen M O'Reilly
    更新日期:2017-11-10
  • Global deworming: moving past albendazole and mebendazole
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-29
    Peter J Hotez
    更新日期:2017-11-10
  • Measuring progress on preventing pneumonia deaths: are we there yet?
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-08-23
    Cynthia G Whitney
    更新日期:2017-11-10
  • Corrections
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-08

    Gsell P-S, Camacho A, Kucharski AJ, et al. Ring vaccination with rVSV-ZEBOV under expanded access in response to an outbreak of Ebola virus disease in Guinea, 2016: an operational and vaccine safety report. Lancet Infect Dis 2017; published online October 9. http://dx.doi.org/10.1016/S1473-3099(17)30541-8—Mosaka Fallah has been added to the author list, Severine Danmadji has been changed to Séverine Danmadji Nadlaou, and Honora Djidonou has been changed to Djidonou A Honora. The affiliation details and Contributors section have been updated to reflect these changes.

    更新日期:2017-11-09
  • Immunogenicity and safety of one versus two doses of tetravalent dengue vaccine in healthy children aged 2–17 years in Asia and Latin America: 18-month interim data from a phase 2, randomised, placebo-controlled study
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-06
    Xavier Sáez-Llorens, Vianney Tricou, Delia Yu, Luis Rivera, José Jimeno, Ana Cecilia Villarreal, Epiphany Dato, Sonia Mazara, Maria Vargas, Manja Brose, Martina Rauscher, Suely Tuboi, Astrid Borkowski, Derek Wallace
    更新日期:2017-11-07
  • Encouraging results but questions remain for dengue vaccine
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-06
    In-Kyu Yoon, Stephen J Thomas
    更新日期:2017-11-07
  • Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trial
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-03
    James G Hakim, Jennifer Thompson, Cissy Kityo, Anne Hoppe, Andrew Kambugu, Joep J van Oosterhout, Abbas Lugemwa, Abraham Siika, Raymond Mwebaze, Aggrey Mweemba, George Abongomera, Margaret J Thomason, Philippa Easterbrook, Peter Mugyenyi, A Sarah Walker, Nicholas I Paton, E Agweng, P Awio, G Bakeinyaga, C Isabirye, U Kabuga, S Kasuswa, M Katuramu, F Kiweewa, H Kyomugisha, E Lutalo, D Mulima, H Musana, G Musitwa, V Musiime, M Ndigendawan, H Namata, J Nkalubo, P Ocitti Labejja, P Okello, P Olal, G Pimundu, P Segonga, F Ssali, Z Tamale, D Tumukunde, W Namala, R Byaruhanga, J Kayiwa, J Tukamushaba, S Abunyang, D Eram, O Denis, R Lwalanda, L Mugarura, J Namusanje, I Nankya, E Ndashimye, E Nabulime, D Mulima, O Senfuma, G Bihabwa, E Buluma, A Elbireer, D Kamya, M Katwere, R Kiggundu, C Komujuni, E Laker, E Lubwama, I Mambule, J Matovu, A Nakajubi, J Nakku, R Nalumenya, L Namuyimbwa, F Semitala, B Wandera, J Wanyama, H Mugerwa, E Ninsiima, T Ssenkindu, S Mwebe, L Atwine, H William, C Katemba, S Abunyang, M Acaku, P Ssebutinde, H Kitizo, J Kukundakwe, M Naluguza, K Ssegawa, Namayanja, F Nsibuka, P Tuhirirwe, M Fortunate, J Acen, J Achidri, A Amone, M Chamai, J Ditai, M Kemigisa, M Kiconco, C Matama, D Mbanza, F Nambaziira, M Owor Odoi, A Rweyora, G Tumwebaze, H Kalanzi, J Katabaazi, A Kiyingi, M Mbidde, M Mugenyi, P Okong, I Senoga, M Abwola, D Baliruno, J Bwomezi, A Kasede, M Mudoola, R Namisi, F Ssennono, S Tuhirwe, G Amone, J Abach, I Aciro, B Arach, P Kidega, J Omongin, E Ocung, W Odong, A Philliam, H Alima, B Ahimbisibwe, E Atuhaire, F Atukunda, G Bekusike, A Bulegyeya, D Kahatano, S Kamukama, J Kyoshabire, A Nassali, A Mbonye, T M Naturinda, Ndukukire, A Nshabohurira, H Ntawiha, A Rogers, M Tibyasa, S Kiirya, D Atwongyeire, A Nankya, C Draleku, D Nakiboneka, D Odoch, L Lakidi, R Ruganda, R Abiriga, M Mulindwa, F Balmoi, S Kafuma, E Moriku, A Reid, E Chidziva, G Musoro, C Warambwa, G Tinago, S Mutsai, M Phiri, S Mudzingwa, T Bafana, V Masore, C Moyo, R Nhema, S Chitongo, Robert Heyderman, Lucky Kabanga, Symon Kaunda, Aubrey Kudzala, Linly Lifa, Jane Mallewa, Mike Moore, Chrissie Mtali, George Musowa, Grace Mwimaniwa, Rosemary Sikwese, Milton Ziwoya, H Chimbaka B Chitete, S Kamanga, T Kayinga E Makwakwa, R Mbiya, M Mlenga, T Mphande, C Mtika, G Mushani, O Ndhlovu, M Ngonga, I Nkhana, R Nyirenda, P Cheruiyot, C Kwobah, W Lokitala Ekiru, M Mokaya, A Mudogo, A Nzioka, M Tanui, S Wachira, K Wools-Kaloustian, P Alipalli, E Chikatula, J Kipaila, I Kunda, S Lakhi, J Malama, W Mufwambi, L Mulenga, P Mwaba, E Mwamba, M Namfukwe, E Kerukadho, B Ngwatu, J Birungi, J Boles, A Burke, L Castle, S Ghuman, L Kendall, S Tebbs, J Whittle, H Wilkes, N Young, M Spyer, C Kapuya, F Kyomuhendo, D Kyakundi, N Mkandawire, S Mulambo, S Senyonjo, B Angus, A Arenas-Pinto, A Palfreeman, F Post, D Ishola, J Arribas, R Colebunders, M Floridia, M Giuliano, P Mallon, P Walsh, M De Rosa, E Rinaldi, I Weller, C Gilks, A Kangewende, S Lakhi, E Luyirika, F Miiro, S Ojoo, S Phiri, A Wapakabulo, T Peto, J Matenga, G Cloherty, J van Wyk, M Norton, S Lehrman, P Lamba, K Malik, J Rooney, W Snowden, J Villacian
    更新日期:2017-11-05
  • The unexpected success of NRTIs in second-line treatment
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-03
    Andrew M Hill, Francois Venter
    更新日期:2017-11-05
  • Effectiveness of national and subnational infection prevention and control interventions in high-income and upper-middle-income countries: a systematic review
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-10-31
    Lesley Price, Jennifer MacDonald, Lynn Melone, Tracey Howe, Paul Flowers, Kay Currie, Evonne Curran, Valerie Ness, Debbie Waddell, Sarkis Manoukian, Agi McFarland, Claire Kilpatrick, Julie Storr, Anthony Twyman, Benedetta Allegranzi, Jacqui Reilly
    更新日期:2017-11-01
  • Comparative pathogenesis of rabies in bats and carnivores, and implications for spillover to humans
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-10-31
    Lineke Begeman, Corine GeurtsvanKessel, Stefan Finke, Conrad M Freuling, Marion Koopmans, Thomas Müller, Tom J H Ruigrok, Thijs Kuiken
    更新日期:2017-11-01
  • Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-10-27
    Laurent Abel, Jacques Fellay, David W Haas, Erwin Schurr, Geetha Srikrishna, Michael Urbanowski, Nimisha Chaturvedi, Sudha Srinivasan, Daniel H Johnson, William R Bishai
    更新日期:2017-10-28
  • Corrections
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-10-26

    Blok DJ, de Vlas SJ, Richardus JH. Finding undiagnosed leprosy cases. Lancet Infect Dis 2016; 16: 1113— In this Correspondence, incorrect colours had been used to label ‘Undiagnosed’ and ‘Diagnosed’ in the key of the figure. Additionally, the data on the x-axis should have started at 1991 and ended at 2040. These corrections have been made to the online version as of October 26, 2017.

    更新日期:2017-10-27
  • Atypical presentation of post-kala-azar dermal leishmaniasis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Quazi Tarikul Islam, Ariful Basher
    更新日期:2017-10-26
  • Criminalising transmission of infections
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    George Mawhinney
    更新日期:2017-10-26
  • Voices on antimicrobial resistance
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Clare Sansom
    更新日期:2017-10-26
  • Research brief
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Dara Mohammadi
    更新日期:2017-10-26
  • Infectious disease surveillance update
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Ruth Zwizwai

    As of Oct 7, the number of people who have died in the cholera epidemic that started in April 2017, in Yemen, has risen to 2151. A total of 800 626 cases have been reported across 22 of the 23 provinces in Yemen. Most of the reported deaths have been from the northern province of Hajjah.

    更新日期:2017-10-26
  • Antibiotic development pipeline slows to a trickle
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Talha Burki
    更新日期:2017-10-26
  • International Forum on Gonococcal Infections and Resistance
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Marco De Ambrogi

    Held in Shenzhen, China (Sept 18–19), the forum was convened to discuss the major challenges in Neisseria gonorrhoeae infection. Marco De Ambrogi reports.

    更新日期:2017-10-26
  • HIV and antenatal care in Sri Lanka: a global health success
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Sophie Cousins

    Sri Lanka's dedication to maternal and antenatal health is helping it to eliminate mother-to-child transmission of HIV. Sophie Cousins reports.

    更新日期:2017-10-26
  • WHO delays guinea-worm disease eradication to 2020: are dogs the sole culprits?
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    M Teresa Galán-Puchades

    WHO's 2007 global plan1 targeted the eradication of guinea-worm disease by 2015. This objective was not met and the culprits have, apparently, been identified. In addition to the political instability that prevails in many areas of Africa, which prevents the applicability of control strategies for disease control, dogs have been considered the most serious obstacle to the eradication because of the number of infected dogs that reside in Chad, Ethiopia, and Mali.2 As a result, WHO has reconsidered the objectives set out in the 2007 global plan, delaying the eradication of guinea-worm disease to 2018 for Mali and South Sudan, to 2019 for Ethiopia, and to 2020 for Chad.

    更新日期:2017-10-26
  • Post-migration follow-up of migrants at risk of tuberculosis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Peter J White, Ibrahim Abubakar, Robert W Aldridge, Andrew C Hayward

    In recent Correspondence about the screening and treatment of latent tuberculosis infection in migrants who had moved from countries with a high tuberculosis burden to low-burden countries, Kayvan Bozorgmehr1 reported that asylum seekers in Germany from Somalia and Iraq had very different prevalences of latent infection. He commented that “Many studies on effectiveness of tuberculosis screening treat migrants as homogenous, neglecting that this population is socially constructed and highly heterogeneous”, citing our study2 as one of the examples.

    更新日期:2017-10-26
  • Itraconazole and antiretroviral therapy: strategies for empirical dosing – Author's reply
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Thuy Le, Antoine Adenis, Andrew Limper, Thomas Harrison

    We thank Ilan S Schwartz and Sean Wasserman for their interest in our paper on the management of HIV-associated endemic mycoses.1 Schwartz and Wasserman rightly express concern regarding the known drug–drug interaction between itraconazole and non-nucleotide reverse transcriptase inhibitors (NNRTIs) efavirenz and nevirapine, which results in considerable reductions in plasma itraconazole concentrations following co-administration. NNRTIs are often included in standardised first-line antiretroviral therapy regimens in developing countries, and co-administration with itraconazole is commonly required during the consolidation and maintenance of therapy for histoplasmosis in Latin America and talaromycosis in Asia.

    更新日期:2017-10-26
  • Itraconazole and antiretroviral therapy: strategies for empirical dosing
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Ilan S Schwartz, Sean Wasserman

    In their Review in, Andrew H Limper and colleagues1 highlight the importance of itraconazole for the management of HIV-associated endemic mycoses. Itraconazole is both a substrate and a potent inhibitor of cytochrome P450 3A4 (CYP3A4) and inhibits the membrane transporter P-glycoprotein, resulting in considerable drug–drug interactions with antiretrovirals.2 The reduction of itraconazole exposure when co-administered with the non-nucleotide reverse transcriptase inhibitors (NNRTIs) efavirenz and nevirapine, which are widely-used in developing countries, is particularly concerning.

    更新日期:2017-10-26
  • Proposed treatment strategies for non-gonococcal urethritis
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Takashi Deguchi

    I read with great interest the Comment by Jørgen S Jensen1 in The Lancet Infectious Diseases about Mycoplasma genitalium infections. As the author notes, the increase in macrolide and fluoroquinolone-resistant M genitalium makes the treatment of M genitalium infections difficult. Under these conditions, new treatment strategies for non-gonococcal urethritis in men are needed. In clinical practice, non-gonococcal urethritis is treated with drugs highly active against Chlamydia trachomatis, because it causes approximately 50% of non-gonococcal urethritis.

    更新日期:2017-10-26
  • Hospital antimicrobial stewardship: the way forward – Authors' reply
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Evelina Tacconelli, Beryl Primrose Gladstone

    We thank Charis Marwick and colleagues and Céline Pulcini and Peter Collignon for their comments on our study.1 As stated in the Discussion section, we completely agree that the possibility of uncontrolled studies having observed effects as a result of an underlying secular trend cannot be ignored, and we also recommended the use of controlled interventional designs for future studies. However, we would like to underline that, although some guidance is available on how to design interventions on antimicrobial stewardship,2 specific recommendations about how to select study designs and overcome major bias in assessing antibiotic stewardship programmes (eg, definitions of outcomes or analytical methods) are missing or under development.

    更新日期:2017-10-26
  • Hospital antimicrobial stewardship: the way forward
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Céline Pulcini, Peter Collignon

    In resource-limited environments, deciding where and how investments should be made to reduce bacterial resistance is challenging.

    更新日期:2017-10-26
  • Hospital antimicrobial stewardship: the way forward
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Charis A Marwick, Bruce Guthrie, Peter G Davey

    We read David Baur and colleagues' systematic review1 of the effect of antimicrobial stewardship programmes on antibiotic resistance and Clostridium difficile infection, and the accompanying Comment,2 with great interest.

    更新日期:2017-10-26
  • Water, sanitation, and hygiene interventions: an urgent requirement in post-flood Nepal
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Om Prasad Gautam, Yael Velleman, Krishna Prasad Paudel, Meghnath Dhimal, Val Curtis

    Another natural disaster struck in Nepal between Aug 11 and Aug 12, 2017, when heavy rainfall caused extensive flooding in 21 Terai (lowland) districts bordering India. By Aug 16, 2017, 75 000 households had been affected and 123 people had been killed.1

    更新日期:2017-10-26
  • The 2017 Dhaka chikungunya outbreak
    Lancet Infect. Dis. (IF 19.864) Pub Date : 2017-11-01
    Iqbal Kabir, Megnath Dhimal, Ruth Müller, Swagata Banik, Ubydul Haque
    更新日期:2017-10-26
Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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