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  • Prescribing sleep for better health
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-17
    Cheryl Lai
    更新日期:2017-11-19
  • The fantastic legacy of Terry Pratchett
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-16
    Andrew Bianchi
    更新日期:2017-11-17
  • Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-16
    Ruth Chia, Adriano Chiò, Bryan J Traynor
    更新日期:2017-11-17
  • Balancing ethics and care in disorders of consciousness
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-15
    Laura Y Cabrera, Judy Illes

    Neuromodulatory interventions that rely on the premise that stimulation activates or promotes brain circuit signals are being applied to a wide range of therapeutic targets in neurological and psychiatric disorders. The numbers of patients with whom these interventions are being tested, the range of approaches, and the variety of methods are all on the rise. Paralleling these trends are the increasing numbers of countries doing clinical trials, and the coverage of them in the press.1

    更新日期:2017-11-16
  • Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Andrew I R Maas, David K Menon, P David Adelson, Nada Andelic, Michael J Bell, Antonio Belli, Peter Bragge, Alexandra Brazinova, András Büki, Randall M Chesnut, Giuseppe Citerio, Mark Coburn, D Jamie Cooper, A Tamara Crowder, Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A van Essen, Valery L Feigin, Guoyi Gao, Joseph Giacino, Laura E Gonzalez-Lara, Russell L Gruen, Deepak Gupta, Jed A Hartings, Sean Hill, Ji-yao Jiang, Naomi Ketharanathan, Erwin J O Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Stefania Mondello, Virginia Newcombe, Aarno Palotie, Paul M Parizel, Wilco Peul, James Piercy, Suzanne Polinder, Louis Puybasset, Todd E Rasmussen, Rolf Rossaint, Peter Smielewski, Jeannette Söderberg, Simon J Stanworth, Murray B Stein, Nicole von Steinbüchel, William Stewart, Ewout W Steyerberg, Nino Stocchetti, Anneliese Synnot, Braden Te Ao, Olli Tenovuo, Alice Theadom, Dick Tibboel, Walter Videtta, Kevin K W Wang, W Huw Williams, Lindsay Wilson, Kristine Yaffe, Hadie Adams, Vanni Agnoletti, Judith Allanson, Krisztina Amrein, Norberto Andaluz, Audny Anke, Anna Antoni, Arjan Bastiaan van As, Gérard Audibert, Antun Azaševac, Philippe Azouvi, Maria Luisa Azzolini, Camelia Baciu, Rafael Badenes, Karen M Barlow, Ronald Bartels, Ursula Bauerfeind, Miriam Beauchamp, Darcy Beer, Ronny Beer, Francisco Javier Belda, Bo-Michael Bellander, Rémy Bellier, Habib Benali, Thierry Benard, Valzerda Beqiri, Luigi Beretta, Francis Bernard, Guido Bertolini, Federico Bilotta, Morten Blaabjerg, Hugo den Boogert, Kathy Boutis, Pierre Bouzat, Brian Brooks, Camilla Brorsson, Monika Bullinger, Emma Burns, Emiliana Calappi, Peter Cameron, Elsa Carise, Ana M Castaño-León, Francesco Causin, Giorgio Chevallard, Arturo Chieregato, Brian Christie, Maryse Cnossen, Jonathan Coles, Johnny Collett, Francesco Della Corte, William Craig, Gabor Csato, Akos Csomos, Nicola Curry, Claire Dahyot-Fizelier, Helen Dawes, Carol DeMatteo, Bart Depreitere, Deborah Dewey, Jeroen van Dijck, Đula Đilvesi, Diederik Dippel, Kemal Dizdarevic, Emma Donoghue, Or Duek, Guy-Loup Dulière, Adelaida Dzeko, George Eapen, Carolyn A Emery, Shane English, Patrick Esser, Erzsébet Ezer, Martin Fabricius, Junfeng Feng, Dean Fergusson, Anthony Figaji, Joanne Fleming, Kelly Foks, Gilles Francony, Stephen Freedman, Ulderico Freo, Shirin K Frisvold, Isabelle Gagnon, Damien Galanaud, Dashiell Gantner, Benoit Giraud, Ben Glocker, Jagoš Golubovic, Pedro A Gómez López, Wayne A Gordon, Primoz Gradisek, Jocelyn Gravel, Donald Griesdale, Francesca Grossi, Juanita A Haagsma, Asta Kristine Håberg, Iain Haitsma, Wim Van Hecke, Raimund Helbok, Eirik Helseth, Caroline van Heugten, Cornelia Hoedemaekers, Stefan Höfer, Lindsay Horton, Jiyuan Hui, Jilske Antonia Huijben, Peter J Hutchinson, Bram Jacobs, Mathieu van der Jagt, Stefan Jankowski, Koen Janssens, Bojan Jelaca, Kelly M Jones, Konstantinos Kamnitsas, Rafael Kaps, Mladen Karan, Ari Katila, Kirsi-Maija Kaukonen, Véronique De Keyser, Riku Kivisaari, Angelos G Kolias, Bálint Kolumbán, Ksenija Kolundžija, Daniel Kondziella, Lars-Owe Koskinen, Noémi Kovács, Andreas Kramer, Demitri Kutsogiannis, Theodoros Kyprianou, Alfonso Lagares, François Lamontagne, Roberto Latini, François Lauzier, Isaac Lazar, Christian Ledig, Rolf Lefering, Valerie Legrand, Leon Levi, Roger Lightfoot, Angels Lozano, Stephen MacDonald, Sebastian Major, Alex Manara, Pauline Manhes, Hugues Maréchal, Costanza Martino, Alessandro Masala, Serge Masson, Julia Mattern, Bradford McFadyen, Catherine McMahon, Maureen Meade, Béla Melegh, Tomas Menovsky, Lynne Moore, Marta Morgado Correia, Maria Cristina Morganti-Kossmann, Holger Muehlan, Pratik Mukherjee, Lynnette Murray, Joukje van der Naalt, Ancuta Negru, David Nelson, Daan Nieboer, Quentin Noirhomme, József Nyirádi, Mauro Oddo, David O Okonkwo, Annemarie W Oldenbeuving, Fabrizio Ortolano, Martin Osmond, Jean-François Payen, Vincent Perlbarg, Paolo Persona, Nicolas Pichon, Anna Piippo-Karjalainen, Sébastien Pili-Floury, Matti Pirinen, Horia Ple, Maria Antonia Poca, Jussi Posti, Dominique Van Praag, Alain Ptito, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Ruben G L Real, Nick Reed, Jonathan Rhodes, Claudia Robertson, Saulius Rocka, Cecilie Røe, Olav Røise, Gerwin Roks, Jonathan Rosand, Jeffrey V Rosenfeld, Christina Rosenlund, Guy Rosenthal, Sandra Rossi, Daniel Rueckert, Godard C W de Ruiter, Marco Sacchi, Barbara J Sahakian, Juan Sahuquillo, Oliver Sakowitz, Gerardo Salvato, Renán Sánchez-Porras, János Sándor, Grinder Sangha, Nadine Schäfer, Silke Schmidt, Kathryn J Schneider, David Schnyer, Herbert Schöhl, Guus G Schoonman, Rico Frederik Schou, Özcan Sir, Toril Skandsen, Dirk Smeets, Abayomi Sorinola, Emmanuel Stamatakis, Ana Stevanovic, Robert D Stevens, Nina Sundström, Fabio Silvio Taccone, Riikka Takala, Päivi Tanskanen, Mark Steven Taylor, Ralph Telgmann, Nancy Temkin, Guido Teodorani, Matt Thomas, Christos M Tolias, Tony Trapani, Alexis Turgeon, Peter Vajkoczy, Alex B Valadka, Egils Valeinis, Shirley Vallance, Zoltán Vámos, Alessia Vargiolu, Emmanuel Vega, Jan Verheyden, Anne Vik, Rimantas Vilcinis, Carmen Vleggeert-Lankamp, Lidia Vogt, Victor Volovici, Daphne C Voormolen, Peter Vulekovic, Thijs Vande Vyvere, Julia Van Waesberghe, Lars Wessels, Eno Wildschut, Guy Williams, Maren K L Winkler, Stefan Wolf, Gordon Wood, Nektaria Xirouchaki, Alexander Younsi, Menashe Zaaroor, Veronika Zelinkova, Roger Zemek, Fabrizio Zumbo
    更新日期:2017-11-15
  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-20
    James F Howard, Kimiaki Utsugisawa, Michael Benatar, Hiroyuki Murai, Richard J Barohn, Isabel Illa, Saiju Jacob, John Vissing, Ted M Burns, John T Kissel, Srikanth Muppidi, Richard J Nowak, Fanny O'Brien, Jing-Jing Wang, Renato Mantegazza, Claudio Gabriel Mazia, Miguel Wilken, Carolina Ortea, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Gonzalo Vidal, Alejandra Dalila Garcia, Phillipa Lamont, Wai-Kuen Leong, Heidi Boterhoven, Beverly Fyfe, Leslie Roberts, Mahi Jasinarachchi, Natasha Willlems, Julia Wanschitz, Wolfgang Löscher, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Linda Wagemaekers, Delphine Mahieu, Philip Van Damme, Charlotte Smetcoren, Olivier Stevens, Sarah Verjans, Ann D'Hondt, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Rosa Hasan, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Ana Paula Melo, Rosana Rocha, Bruno Rosa, Thabata Veiga, Luiz Augusto da Silva, Jordana Gonçalves Geraldo, Maria da Penha Morita Ananias, Erica Nogueira Coelho, Gabriel Paiva, Marina Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Erica Coelho, Luciana Renata Cubas Volpe, Gustavo Duran, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Luciana Souza Duca, Tomás Augusto Suriane Fialho, Maurício André Gheller Friedrich, Alexandre Guerreiro, Henrique Mohr, Maurer Pereira Martins, Daiane da Cruz Pacheco, Ana Paula Macagnan, Aline de Cassia Santos, Acary Souza Bulle Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Valeria Cavalcante Lino, Wladimir Pinto, Carolina Miranda, Fernanda Carrara, Iandra Souza, Angela Genge, Rami Massie, Natasha Campbell, Vera Bril, Hans Katzberg, Mehran Soltani, Eduardo Ng, Zaeem Siddiqi, Celile Phan, Derrick Blackmore, Stanislav Vohanka, Josef Bednarik, Magda Chmelikova, Marek Cierny, Stanislava Toncrova, Jana Junkerova, Barbora Kurkova, Katarina Reguliova, Olga Zapletalova, Jiri Pitha, Iveta Novakova, Michaela Tyblova, Marcela Wolfova, Ivana Jurajdova, Henning Andersen, Thomas Harbo, Lotte Vinge, Anita Mogensen, Joan Højgaard, Nanna Witting, Anne Mette Autzen, Jane Pedersen, Markus Färkkilä, Sari Atula, Anne Nyrhinen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Jaana Eriksson, Tuula Harrison, Claude Desnuelle, Sabrina Sacconi, Marie-Hélène Soriani, Sonia Decressac, Julie Moutarde, Pauline Lahaut, Guilhem Solé, Gwendal Le Masson, Anne-Cécile Wielanek-Bachelet, Morgane Gaboreau, Caroline Moreau, Amy Wilson, Christophe Vial, Françoise Bouhour, Helene Gervais-Bernard, Hélène Merle, Caroline Hourquin, Arnaud Lacour, Olivier Outteryck, Patrick Vermersch, Hélène Zephir, Edouard Millois, Michel Deneve, Fabienne Deruelle, Benedikt Schoser, Stephan Wenninger, Martin Stangel, Sascha Alvermann, Stefan Gingele, Thomas Skripuletz, Kurt-Wolfram Suehs, Corinna Trebst, Karin Fricke, Sotirios Papagiannopoulos, Sevasti Bostantzopoulou, Nicholas Vlaikidis, Martha Zampaki, Nikoletta Papadopoulou, Dimos-Dimitrios Mitsikostas, Eleni Kasioti, Efstathia Mitropoulou, Despoina Charalambous, Csilla Rozsa, Melinda Horvath, Gabor Lovas, Judit Matolcsi, Gyorgyi Szabo, Brigitta Szabadosne, Laszlo Vecsei, Livia Dezsi, Edina Varga, Monika Konyane, Bella Gross, Olga Azrilin, Nelly Greenbereg, Hila Bali Kuperman, Giovanni Antonini, Matteo Garibaldi, Stefania Morino, Fernanda Troili, Antonella Di Pasquale, Alessandro Filla, Teresa Costabile, Enrico Marano, Francesco Sacca, Angela Marsil, Giorgia Puorro, Michelangelo Maestri Tassoni, Anna De Rosa, Silvia Bonanno, Carlo Antozzi, Lorenzo Maggi, Angela Campanella, Corrado Angelini, Paola Cudia, Valentina Pegoraro, Elena Pinzan, Francesca Bevilacqua, Daniele Orrico, Domenico Marco Bonifati, Amelia Evoli, Paolo Emilio Alboini, Valentina D'Amato, Raffaele Iorio, Maurizio Inghilleri, Laura Fionda, Vittorio Frasca, Elena Giacomelli, Maria Gori, Diego Lopergolo, Emanuela Onesti, Maria Gabriele, Francesco Patti, Andrea Salvatore Caramma, Silvia Messina, Ester Reggio, Cinzia Caserta, Akiyuki Uzawa, Tetsuya Kanai, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Yuriko Nagane, Ikuko Kamegamori, Yuko Fujii, Kazumi Futono, Tomoko Tsuda, Yuka Saito, Hidekazu Suzuki, Miyuki Morikawa, Makoto Samukawa, Sachiko Kamakura, Hirokazu Shiraishi, Teiichiro Mitazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Tomomi Kobashikawa, Megumi Koga, Yasuko Maeda, Kazumi Takada, Mihoko Takada Takada, Yumi Yamashita, Seiko Yoshida, Yasushi Suzuki, Tetsuya Akiyama, Koichi Narikawa, Kenichi Tsukita, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Hidenori Matsuo, Takayasu Fukudome, Yuichiro Gondo, Yasuhiro Maeda, Akiko Nagaishi, Shunya Nakane, Yoshinori Okubo, Meinoshin Okumura, Soichiro Funaka, Tomohiro Kawamura, Masayuki Makamori, Masanori Takahashi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Namie Taichi, Emiko Tsuda, Takashi Hayashi, Shin Hisahara, Tomihiro Imai, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shun Shimohama, Shuichiro Suzuki, Daisuke Yamamoto, Shingo Konno, Tomomi Imamura, Masashi Inoue, Mayumi Murata, Hiroshi Nakazora, Ritsu Nakayama, Yasuko Ikeda, Miki Ogawa, Maoko Shirane, Takashi Kanda, Motoharu Kawai, Michiaki Koga, Junichi Ogasawara, Masatoshi Omoto, Yasuteru Sano, Hideki Arima, Sachie Fukui, Shigemi Shimose, Hirokazu Shinozaki, Masanori Watanabe, Chieko Yoshikawa, Anneke van der Kooi, Marianne de Visser, Tamar Gibson, Jos Maessen, Marc de Baets, Catherine Faber, Maria Johanna Keijzers, Monique Miesen, Anna Kostera-Pruszczyk, Anna Kaminska, Byung-Jo Kim, Chang Nyoung Lee, Yong Seo Koo, Hung Youl Seok, Hoo Nam Kang, HyeJin Ra, Byoung Joon Kim, Eun Bin Cho, HyeLim Lee, Ju-Hong Min, Jinmyoung Seok, Da Yoon Koh, JuYoung Kwon, JiEun Lee, SangAe Park, Yoon-Ho Hong, Jae-Sung Lim, MiRi Kim, Seung Min Kim, Yool-hee Kim, Hyung Seok Lee, Ha Young Shin, Eun Bi Hwang, MiJu Shin, Denis Sazonov, Asya Yarmoschuk, Larisa Babenko, Nadezhda Malkova, Anna Melnikova, Denis Korobko, Evgeniya Kosykh, Dmitry Pokhabov, Yulia Nesterova, Vladislav Abramov, Victor Balyazin, Carlos Casasnovas Pons, Maria Alberti Aguilo, Christian Homedes-Pedret, Natalia Julia Palacios, Ana Lazaro, Exuperio Diez Tejedor, Mireya Fernandez-Fournier, Pedro Lopez Ruiz, Francisco Javier Rodriguez de Rivera, Maria Salvado Figueras, Josep Gamez, Maria Salvado, Elena Cortes Vicente, Jordi Diaz-Manera, Luis Querol Gutierrez, Ricardo Rojas Garcia, Nuria Vidal, Elisabet Arribas-Ibar, Fredrik Piehl, Albert Hietala, Lena Bjarbo, Christopher Lindberg, Daniel Jons, Blanka Andersson, Ihsan Sengun, Pinar Ozcelik, Celal Tuga, Muzeyyen Ugur, Cavit Boz, Didem Altiparmak, Sibel Gazioglu, Cigdem Ozen Aydin, Sevim Erdem-Ozdamar, Can Ebru Bekircan-Kurt, Ezgi Yilmaz, Nazire Pinar Acar, Yagmur Caliskan, Husnu Efendi, Seda Aydinlik, Hakan Cavus, Cansu Semiz, Ozlem Tun, Murat Terzi, Baki Dogan, Musa Kazim Onar, Sedat Sen, Tugce Kirbas Cavdar, Fiona Norwood, Aikaterini Dimitriou, Jakit Gollogly, Mohamed Mahdi-Rogers, Arshira Seddigh, Gal Maier, Faisal Sohail, Sivakumar Sathasivam, Heike Arndt, Debbie Davies, Dave Watling, Michael Rivner, J. Edward Hartmann, Brandy Quarles, Nicole Smalley, Anthony Amato, Thomas Cochrane, Mohammed Salajegheh, Kristen Roe, Katherine Amato, Shirli Toska, Gil Wolfe, Nicholas Silvestri, Kara Patrick, Karen Zakalik, Jonathan Katz, Robert Miller, Marguerite Engel, Elena Bravver, Benjamin Brooks, Sarah Plevka, Maryanne Burdette, Mohammad Sanjak, Megan Kramer, Joanne Nemeth, Clara Schommer, Vern Juel, Jeffrey Guptill, Lisa Hobson-Webb, Kate Beck, Donna Carnes, John Loor, Amanda Anderson, Dale Lange, Eliz Agopian, Jonathan Goldstein, Erin Manning, Lindsay Kaplan, Shara Holzberg, Nicole Kassebaum, Robert Pascuzzi, Cynthia Bodkin, John Kincaid, Riley Snook, Sandra Guinrich, Angela Micheels, Vinay Chaudhry, Andrea Corse, Betsy Mosmiller, Doreen Ho, Jayashri Srinivasan, Michael Vytopil, Nicholas Ventura, Stephanie Scala, Cynthia Carter, Craig Donahue, Carol Herbert, Elaine Weiner, Jonathan McKinnon, Laura Haar, Naya McKinnon, Karan Alcon, Kevin Daniels, Nadia Sattar, Dennis Jeffery, Kaitlyn McKenna, Amanda Guidon, William David, Christina Dheel, Mark Levine-Weinberg, Catherine Nigro, Ericka Simpson, Stanley H Appel, Eugene Lai, Luis Lay, Jr, Milvia Pleitez, Sharon Halton, Casey Faigle, Lisa Thompson, Mark Sivak, Susan Shin, Joan Bratton, Daniel Jacobs, Gavin Brown, Ibrez Bandukwala, Morris Brown, Jennifer Kane, Ira Blount, Miriam Freimer, J. Chad Hoyle, Julie Agriesti, Julie Khoury, Tessa Marburger, Harpreet Kaur, Diana Dimitrova, Michelle Mellion, George Sachs, Brigid Crabtree, Roseann Keo, Ele Kim Perez, Sandra Taber, James Gilchrist, Angela Andoin, Taylor Darnell, Neelam Goyal, Sarada Sakamuri, Yuen T So, Lesly Welsh Welsh, Ratna Bhavaraju-Sanka, Alejandro Tobon Gonzalez, Floyd Jones, Amy Saklad, Sharon Nations, Jaya Trivedi, Steve Hopkins, Mohamed Kazamel, Mohammad Alsharabati, Liang Lu, Sandi Mumfrey-Thomas, Amy Woodall, David Richman, Janelle Butters, Molly Lindsay, Tahseen Mozaffar, Tiyonnoh Cash, Namita Goyal, Gulmohor Roy, Veena Mathew, Fatima Maqsood, Brian Minton, H. James Jones, Jeffrey Rosenfeld, Rebekah Garcia, Sonia Garcia, Laura Echevarria, Michael Pulley, Shachie Aranke, Alan Ross Berger, Jaimin Shah, Yasmeen Shabbir, Lisa Smith, Mary Varghese, Laurie Gutmann, Ludwig Gutmann, Andrea Swenson, Heena Olalde, Charlene Hafer-Macko, Justin Kwan, Lindsay Zilliox, Karen Callison, Beth DiSanzo, Kerry Naunton, Martin Bilsker, Khema Sharma, Eliana Reyes, Anne Cooley, Sara-Claude Michon, Julie Steele, Chafic Karam Karam, Manisha Chopra, Shawn Bird, Jacob Kaufman, Nichole Gallatti, Tuan Vu, Lara Katzin, Terry McClain, Brittany Harvey, Adam Hart, Kristin Huynh, Said Beydoun, Amaiak Chilingaryan, Brian Droker, Frank Lin, Akshay Shah, Anh Tran, Salma Akhter, Ali Malekniazi, Rup Tandan, Michael Hehir, Waqar Waheed, Shannon Lucy, Michael Weiss, Jane Distad, Sharon Downing, Susan Strom, Robert Lisak, Evanthia Bernitsas, Omar Khan, Shitiz Kumar Sriwastava, Alexandros Tselis, Kelly Jia, Tulio Bertorini, Thomas Arnold, Kendrick Henderson, Rekha Pillai, Ye Liu, Lauren Wheeler, Jasmine Hewlett, Mollie Vanderhook, Daniel Dicapua, Benison Keung, Aditya Kumar, Huned Patwa, Kimberly Robeson, Joan Nye, Hong Vu
    更新日期:2017-11-15
  • 24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-30
    Hilkka Soininen, Alina Solomon, Pieter Jelle Visser, Suzanne B Hendrix, Kaj Blennow, Miia Kivipelto, Tobias Hartmann, Ilona Hallikainen, Merja Hallikainen, Seppo Helisalmi, Tarja Lappalainen, Yawu Liu, Teemu Paajanen, Lars-Olof Wahlund, Yvonne Freund-Levi, Niels Andreasen, Göran Hagman, Stina Lindblom, Klaus Fassbender, Matthias Riemenschneider, Marcus OW Grimm, Aline Klees-Rollmann, Maxine Luley, Epameinondas Lyros, Robert Schomburg, Jennifer Kennel, Daniela Ramelli, Lutz Frölich, Lucrezia Hausner, Christoph Laske, Thomas Leyhe, Christian Mychajliw, Niklas Koehler, Stephan Schiekofer, Hans Klünemann, Johannes Schröder, Dieter Lütjohann, Philip Scheltens, Ineke van Rossum, Nienke Scheltens, Daniela Bertens, Mara ten Kate, Frederik Barkhof, Johanna ML Henselmans, Gerwin Roks, Anneke MJ van Hees, Noel Ellison
    更新日期:2017-11-15
  • The mind's secrets brought to life
    Lancet Neurol. (IF 26.284) Pub Date : 2017-07-12
    Anna Kennedy
    更新日期:2017-11-15
  • Keeping an open mind about autism
    Lancet Neurol. (IF 26.284) Pub Date : 2017-07-12
    Angela Bonsu
    更新日期:2017-11-15
  • The longest sleep
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    Clare Caldwell, Matthew Kiernan
    更新日期:2017-11-15
  • Sonja Scholz
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    更新日期:2017-11-15
  • Eric Reiman: aiming to prevent Alzheimer's disease
    Lancet Neurol. (IF 26.284) Pub Date : 2017-06-30
    Tony Kirby
    更新日期:2017-11-15
  • The CENTER-TBI core study: The making-of
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Adrian Burton
    更新日期:2017-11-15
  • Portrayal of progressive supranuclear palsy in the 16th century
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    Peter LeWitt
    更新日期:2017-11-15
  • Chelated or dechelated gadolinium deposition – Authors' reply
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    Vikas Gulani, Fernando Calamante, Frank G Shellock, Emanuel Kanal, Scott B Reeder

    We thank Alexander Radbruch and colleagues for their comments regarding our and more recent publications. They highlight an experiment comparing gadolinium retention in the rat brain after high doses of linear or macrocyclic gadolinium-based contrast agents (GBCAs),1 demonstrating retention of tiny amounts of soluble gadolinium in brain tissue for all agents, but higher concentrations of the insoluble fraction for linear than for macrocyclic agents. Of note, another paper2 by the same group reported that brain tissue of rats with proven gadolinium deposition showed no histopathological changes with either linear or macrocyclic agents.

    更新日期:2017-11-15
  • Chelated or dechelated gadolinium deposition
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    Alexander Radbruch, Donna R Roberts, Olivier Clement, Alex Rovira, Carlo Cosimo Quattrocchi

    Although Vikas Gulani and colleagues1 cite most of the recent literature on gadolinium deposition in their Personal View, we believe that pharmacokinetic evidence obtained from recently published studies2–4 in rats should have also been discussed.

    更新日期:2017-11-15
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01

    Kathrin Reetz, Imis Dogan, Ralf-Dieter Hilgers, et al, for the EFACTS Study Group. Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 2 year cohort study. Lancet Neurol 2016; 15: 1346–54—This Article has been updated so that the members of the EFACTS Study Group are now indexed as authors. This correction has been made to the online version as of Nov 14, 2017.

    更新日期:2017-11-15
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01

    Wild E J, Tabrizi S J. Therapies targeting DNA and RNA in Huntington's disease. Lancet Neurol 2017; 16: 837–47—In table 1, the final row and footnote have been updated to reflect that CHDI Foundation's small-molecule huntingtin-lowering programme is currently at the screening stage and that the mechanisms of action, route of delivery, and advantages and disadvantages of the small molecules being investigated remain to be determined. This correction has been made to the online version as of Nov 14, 2017.

    更新日期:2017-11-15
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01

    Howard J F Jr, Utsugisawa K, Benatar M, et al. Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. Lancet Neurol 2017; 16: 976–86—In this Article, (published online Oct 20), the p value for one of the datapoints in figure 2 should be 0·0007. Additionally, in the sentence ‘Half of all patients reported their worst MGFA classification since diagnosis as class IV or V’ on page 6, the citation at the end of the sentence should be ‘appendix’.

    更新日期:2017-11-15
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-16

    Terkelsen A J, Karlsson P, Lauria G, Freeman R, Finnerup N B, Jensen T S. The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes. Lancet Neurol 2017; 16: 934–44. The declaration of interests section of this article should have stated, “AJT has participated in an investigator-sponsored study provided by Sanofi Genzyme and Alynylam Pharmaceuticals.” This correction has been made to the online version as of Oct 16, 2017.

    更新日期:2017-11-15
  • Neurodegeneration in histiocytoses might start in utero
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-27
    Julien Haroche, Fleur Cohen-Aubart, Jean-François Emile, Jean Donadieu, Zahir Amoura

    Histiocytic disorders, such as Langerhans cell histiocytosis and Erdheim-Chester disease, are characterised by inflammation and accumulation of cells derived from the monocyte and macrophage lineages, resulting in tissue damage.1 Neurodegenerative lesions in Langerhans cell histiocytosis are a devastating type of CNS involvement—different from tumour infiltration—in which patients present with progressive symmetric cerebellar syndrome, tetrapyramidal syndrome with or without motor deficits, pseudobulbar palsy, or cognitive impairment.

    更新日期:2017-11-15
  • Traumatic brain injury: a priority for public health policy
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Gianluca Quaglio, Maurizio Gallucci, Helmut Brand, Amr Dawood, Francesco Cobello

    The Lancet Neurology Commission1 draws attention to the devastating impact of traumatic brain injury (TBI) on patients and their families, and the huge public health burden and economic cost of TBI globally. About 50–60 million new TBI cases are estimated to occur annually, with 2·5 million occurring in the European Union.1 The burden of TBI is greatest in low-income and middle-income countries, where 90% of trauma-related deaths occur.2,3 The Commission sets priorities for prevention, clinical care, and research, calling for a combination of innovative research methods and global collaboration to address the huge but poorly recognised public health challenge of TBI, with steps to ensure that developments in care and progress in research are effectively translated into clinical practice and public health policy.

    更新日期:2017-11-15
  • Traumatic brain injury: a global challenge
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Walter D Johnson, Dylan P Griswold
    更新日期:2017-11-15
  • Eculizumab: a treatment option for mysthenia gravis?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-20
    Nils Erik Gilhus

    Eculizumab is an expensive, humanised monoclonal antibody against the terminal complement protein C5. The drug was patented in 2007, and has since been used and approved for two rare diseases, paroxysmal nocturnal haemoglobulinuria and atypical haemolytic ureamic syndrome. Additionally, eculizumab has been used off-label, which constitutes up to a half of its use in some countries,1 for at least 25 different conditions. Refractory and generalised myasthenia gravis with anti-acetylcholine receptor antibodies is a rare disease that involves the complement system and for which eculizumab has a potential effect.

    更新日期:2017-11-15
  • Targeting prodromal Alzheimer's disease: too late for prevention?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-30
    Hussein N Yassine

    Prodromal Alzheimer's disease is a novel area of research, with clinical research definitions still under development. The LipiDiDiet trial,1 published in The Lancet Neurology, was one of the first completed trials based on the International Working Group (IWG-1) criteria for prodromal Alzheimer's disease.2 The study was a non-pharmacological intervention (medical food Souvenaid) in prodromal Alzheimer's disease.

    更新日期:2017-11-15
  • Alzheimer's disease: evolution of research diagnostic criteria
    Lancet Neurol. (IF 26.284) Pub Date : 2017-12-01
    The Lancet Neurology
    更新日期:2017-11-15
  • Risk of natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: a retrospective analysis of data from four clinical studies
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-29
    Pei-Ran Ho, Harold Koendgen, Nolan Campbell, Bill Haddock, Sandra Richman, Ih Chang
    更新日期:2017-11-10
  • Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-11
    Keith A Josephs, Dennis W Dickson, Nirubol Tosakulwong, Stephen D Weigand, Melissa E Murray, Leonard Petrucelli, Amanda M Liesinger, Matthew L Senjem, Anthony J Spychalla, David S Knopman, Joseph E Parisi, Ronald C Petersen, Clifford R Jack, Jennifer L Whitwell
    更新日期:2017-11-10
  • Large-scale identification of clinical and genetic predictors of motor progression in patients with newly diagnosed Parkinson's disease: a longitudinal cohort study and validation
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-25
    Jeanne C Latourelle, Michael T Beste, Tiffany C Hadzi, Robert E Miller, Jacob N Oppenheim, Matthew P Valko, Diane M Wuest, Bruce W Church, Iya G Khalil, Boris Hayete, Charles S Venuto
    更新日期:2017-11-10
  • Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-17
    Valery L Feigin, Amanuel Alemu Abajobir, Kalkidan Hassen Abate, Foad Abd-Allah, Abdishakur M Abdulle, Semaw Ferede Abera, Gebre Yitayih Abyu, Muktar Beshir Ahmed, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Rufus Olusola Akinyemi, Samer Alabed, Rajaa Al-Raddadi, Nelson Alvis-Guzman, Azmeraw T. Amare, Hossein Ansari, Palwasha Anwari, Johan Ärnlöv, Hamid Asayesh, Solomon Weldegebreal Asgedom, Tesfay Mehari Atey, Leticia Avila-Burgos, Euripide Frinel, G. Arthur Avokpaho, Mahmood Reza Azarpazhooh, Aleksandra Barac, Miguel Barboza, Suzanne L Barker-Collo, Till Bärnighausen, Neeraj Bedi, Ettore Beghi, Derrick A Bennett, Isabela M Bensenor, Adugnaw Berhane, Balem Demtsu Betsu, Soumyadeep Bhaumik, Sait Mentes Birlik, Stan Biryukov, Dube Jara Boneya, Lemma Negesa Bulto Bulto, Hélène Carabin, Daniel Casey, Carlos A. Castañeda-Orjuela, Ferrán Catalá-López, Honglei Chen, Abdulaal A Chitheer, Rajiv Chowdhury, Hanne Christensen, Lalit Dandona, Rakhi Dandona, Gabrielle A de Veber, Samath D Dharmaratne, Huyen Phuc Do, Klara Dokova, E Ray Dorsey, Richard G Ellenbogen, Sharareh Eskandarieh, Maryam S Farvid, Seyed-Mohammad Fereshtehnejad, Florian Fischer, Kyle J Foreman, Johanna M Geleijnse, Richard F Gillum, Giorgia Giussani, Ellen M Goldberg, Philimon N Gona, Alessandra Carvalho Goulart, Harish Chander Gugnani, Rahul Gupta, Vladimir Hachinski, Rajeev Gupta, Randah Ribhi Hamadeh, Mitiku Hambisa, Graeme J Hankey, Habtamu Abera Hareri, Rasmus Havmoeller, Simon I Hay, Pouria Heydarpour, Peter J Hotez, Mihajlo (Michael) B Jakovljevic, Mehdi Javanbakht, Panniyammakal Jeemon, Jost B Jonas, Yogeshwar Kalkonde, Amit Kandel, André Karch, Amir Kasaeian, Anshul Kastor, Peter Njenga Keiyoro, Yousef Saleh Khader, Ibrahim A Khalil, Ejaz Ahmad Khan, Young-Ho Khang, Abdullah Tawfih, Abdullah Khoja, Jagdish Khubchandani, Chanda Kulkarni, Daniel Kim, Yun Jin Kim, Mika Kivimaki, Yoshihiro Kokubo, Soewarta Kosen, Michael Kravchenko, Rita Vanmala Krishnamurthi, Barthelemy Kuate Defo, G Anil Kumar, Rashmi Kumar, Hmwe H Kyu, Anders Larsson, Pablo M Lavados, Yongmei Li, Xiaofeng Liang, Misgan Legesse Liben, Warren D Lo, Giancarlo Logroscino, Paulo A Lotufo, Clement T Loy, Mark T Mackay, Hassan Magdy Abd El Razek, Mohammed Magdy Abd El Razek, Azeem Majeed, Reza Malekzadeh, Treh Manhertz, Lorenzo G Mantovani, João Massano, Mohsen Mazidi, Colm McAlinden, Suresh Mehata, Man Mohan Mehndiratta, Ziad A Memish, Walter Mendoza, Mubarek Abera Mengistie, George A Mensah, Atte Meretoja, Haftay Berhane Mezgebe, Ted R Miller, Shiva Raj Mishra, Norlinah Mohamed Ibrahim, Alireza Mohammadi, Kedir Endris Mohammed, Shafiu Mohammed, Ali H Mokdad, Maziar Moradi-Lakeh, Ilais Moreno Velasquez, Kamarul Imran Musa, Mohsen Naghavi, Josephine Wanjiku Ngunjiri, Cuong Tat Nguyen, Grant Nguyen, Quyen Le Nguyen, Trang Huyen Nguyen, Emma Nichols, Dina Nur Anggraini Ningrum, Vuong Minh Nong, Bo Norrving, Jean Jacques N Noubiap, Felix Akpojene Ogbo, Mayowa O Owolabi, Jeyaraj D. Pandian, Priyakumari Ganesh Parmar, David M Pereira, Max Petzold, Michael Robert Phillips, Michael A Piradov, Richie G. Poulton, Farshad Pourmalek, Mostafa Qorbani, Anwar Rafay, Mahfuzar Rahman, Mohammad HifzUr Rahman, Rajesh Kumar Rai, Sasa Rajsic, Annemarei Ranta, Salman Rawaf, Andre M.N. Renzaho, Mohammad Sadegh Rezai, Gregory A Roth, Gholamreza Roshandel, Enrico Rubagotti, Perminder Sachdev, Saeid Safiri, Ramesh Sahathevan, Mohammad Ali Sahraian, Abdallah M. Samy, Paula Santalucia, Itamar S Santos, Benn Sartorius, Maheswar Satpathy, Monika Sawhney, Mete I Saylan, Sadaf G Sepanlou, Masood Ali Shaikh, Raad Shakir, Morteza Shamsizadeh, Kevin N Sheth, Mika Shigematsu, Haitham Shoman, Diego Augusto Santos Silva, Mari Smith, Eugene Sobngwi, Luciano A Sposato, Jeffrey D Stanaway, Dan J Stein, Timothy J Steiner, Lars Jacob Stovner, Rizwan Suliankatchi Abdulkader, Cassandra EI Szoeke, Rafael Tabarés-Seisdedos, David Tanne, Alice M Theadom, Amanda G Thrift, David L Tirschwell, Roman Topor-Madry, Bach Xuan Tran, Thomas Truelsen, Kald Beshir Tuem, Kingsley Nnanna Ukwaja, Olalekan A Uthman, Yuri Y Varakin, Tommi Vasankari, Narayanaswamy Venketasubramanian, Vasiliy Victorovich Vlassov, Fiseha Wadilo, Tolassa Wakayo, Mitchell T Wallin, Elisabete Weiderpass, Ronny Westerman, Tissa Wijeratne, Charles Shey Wiysonge, Minyahil Alebachew Woldu, Charles D A Wolfe, Denis Xavier, Gelin Xu, Yuichiro Yano, Hassen Hamid Yimam, Naohiro Yonemoto, Chuanhua Yu, Zoubida Zaidi, Maysaa El Sayed Zaki, Joseph R Zunt, Christopher J L Murray, Theo Vos
    更新日期:2017-11-10
  • Flashing lights and poor funding: more than a headache
    Lancet Neurol. (IF 26.284) Pub Date : 2017-08-16
    Cheryl Lai
    更新日期:2017-11-10
  • Moving in the right direction?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-07-19
    Jules Morgan
    更新日期:2017-11-10
  • Conversations with a neuroscientist
    Lancet Neurol. (IF 26.284) Pub Date : 2017-07-11
    Cheryl Lai
    更新日期:2017-11-10
  • The Rhythms of Thought
    Lancet Neurol. (IF 26.284) Pub Date : 2017-07-05
    Robert Stirrups
    更新日期:2017-11-10
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-08-23

    Lai C. Flashing lights and poor funding: more than a headache. Lancet Neurol 2017; published online Aug 16. http://dx.doi.org/10.1016/S1474-4422(17)30285-5—In this Radio review, the affiliation for Peter Goadsby should have been King's College London. This correction has been made to the online version as of Aug 23, 2017.

    更新日期:2017-11-10
  • PML risk and natalizumab: the elephant in the room
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-29
    Tobias Derfuss, Ludwig Kappos

    Natalizumab is one of the most effective therapies currently available for relapsing-remitting multiple sclerosis.1 With the exception of rare hypersensitivity reactions, monthly intravenous infusions are well tolerated and, for most patients, treatment is not associated with an increase in infections.2 But, for unknown reasons, progressive multifocal leukoencephalopathy (PML), an opportunistic, disabling, and life-threatening disease caused by the John Cunningham virus (JCV), is associated with natalizumab treatment.

    更新日期:2017-11-10
  • Predicting progression in patients with Parkinson's disease
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-25
    Cornelis Blauwendraat, Sara Bandrés-Ciga, Andrew B Singleton

    A major challenge to patients, clinicians, family members, and scientists is the unpredictable future that accompanies a diagnosis of Parkinson's disease. When met with the question “what does my future hold?” it is difficult to give predictions that are likely to be useful to the patient. Some individuals will face features that rapidly and adversely affect their quality of life; others will experience a prolonged and fairly benign course, initially well managed by drugs and lifestyle changes. Variability between patients in core features of this multisystem disease—eg, motor decline, neuropsychiatric changes, mood disorders, dysautonomic signs, and fatigue—is the rule.

    更新日期:2017-11-10
  • Global burden of neurological disease: what's in a name?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-09-17
    James J Sejvar

    We are living in a rapidly changing landscape in terms of global public health. On one hand, the immense increase in and ageing of the world's population, mass migration of people from rural to urban areas, and unhealthy lifestyles—either by choice or by circumstance—are negatively affecting the overall health of the planet. On the other hand, medical advances such as vaccines, antibiotics, and new medications, and renewed emphasis on workplace safety, have benefitted global health. These balancing influences perhaps have the most effect on neurological diseases, which affect many different daily functions and therefore have a disproportionately large effect on global health.

    更新日期:2017-11-10
  • Subcutaneous IgG for chronic inflammatory demyelinating polyneuropathy
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Marinos C Dalakas

    Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common chronic autoimmune neuropathy and often responds to corticosteroids, plasmapheresis, and intravenous immunoglobulin (IVIg).1 The only US Food and Drug Administration-approved, and the most commonly applied therapy, is IVIg, which, at 2 g/kg followed by 1 g/kg every 3–4 weeks, has been shown to prevent relapses and maintain stability in 75% of patients.2 Subcutaneous immunoglobulin (SCIg), an alternative route of IgG administration, is approved for IgG replacement therapy in primary immunodeficiency,3 but whether or not it has an effect in balancing immune dysregulation in autoimmune diseases, as IVIg does,4 has not been formally tested.

    更新日期:2017-11-07
  • The CENTER-TBI core study: The making-of
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Adrian Burton
    更新日期:2017-11-07
  • Traumatic brain injury: a global challenge
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Walter D Johnson, Dylan P Griswold
    更新日期:2017-11-07
  • Traumatic brain injury: a priority for public health policy
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Gianluca Quaglio, Maurizio Gallucci, Helmut Brand, Amr Dawood, Francesco Cobello

    The Lancet Neurology Commission1 draws attention to the devastating impact of traumatic brain injury (TBI) on patients and their families, and the huge public health burden and economic cost of TBI globally. About 50–60 million new TBI cases are estimated to occur annually, with 2·5 million occurring in the European Union.1 The burden of TBI is greatest in low-income and middle-income countries, where 90% of trauma-related deaths occur.2,3 The Commission sets priorities for prevention, clinical care, and research, calling for a combination of innovative research methods and global collaboration to address the huge but poorly recognised public health challenge of TBI, with steps to ensure that developments in care and progress in research are effectively translated into clinical practice and public health policy.

    更新日期:2017-11-07
  • Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Andrew I R Maas, David K Menon, P David Adelson, Nada Andelic, Michael J Bell, Antonio Belli, Peter Bragge, Alexandra Brazinova, András Büki, Randall M Chesnut, Giuseppe Citerio, Mark Coburn, D Jamie Cooper, A Tamara Crowder, Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A van Essen, Valery L Feigin, Guoyi Gao, Joseph Giacino, Laura E Gonzalez-Lara, Russell L Gruen, Deepak Gupta, Jed A Hartings, Sean Hill, Ji-yao Jiang, Naomi Ketharanathan, Erwin J O Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Stefania Mondello, Virginia Newcombe, Aarno Palotie, Paul M Parizel, Wilco Peul, James Piercy, Suzanne Polinder, Louis Puybasset, Todd E Rasmussen, Rolf Rossaint, Peter Smielewski, Jeannette Söderberg, Simon J Stanworth, Murray B Stein, Nicole von Steinbüchel, William Stewart, Ewout W Steyerberg, Nino Stocchetti, Anneliese Synnot, Braden Te Ao, Olli Tenovuo, Alice Theadom, Dick Tibboel, Walter Videtta, Kevin K W Wang, W Huw Williams, Lindsay Wilson, Kristine Yaffe, Hadie Adams, Vanni Agnoletti, Judith Allanson, Krisztina Amrein, Norberto Andaluz, Audny Anke, Anna Antoni, Arjan Bastiaan van As, Gérard Audibert, Antun Azaševac, Philippe Azouvi, Maria Luisa Azzolini, Camelia Baciu, Rafael Badenes, Karen M Barlow, Ronald Bartels, Ursula Bauerfeind, Miriam Beauchamp, Darcy Beer, Ronny Beer, Francisco Javier Belda, Bo-Michael Bellander, Rémy Bellier, Habib Benali, Thierry Benard, Valzerda Beqiri, Luigi Beretta, Francis Bernard, Guido Bertolini, Federico Bilotta, Morten Blaabjerg, Hugo den Boogert, Kathy Boutis, Pierre Bouzat, Brian Brooks, Camilla Brorsson, Monika Bullinger, Emma Burns, Emiliana Calappi, Peter Cameron, Elsa Carise, Ana M Castaño-León, Francesco Causin, Giorgio Chevallard, Arturo Chieregato, Brian Christie, Maryse Cnossen, Jonathan Coles, Johnny Collett, Francesco Della Corte, William Craig, Gabor Csato, Akos Csomos, Nicola Curry, Claire Dahyot-Fizelier, Helen Dawes, Carol DeMatteo, Bart Depreitere, Deborah Dewey, Jeroen van Dijck, Đula Đilvesi, Diederik Dippel, Kemal Dizdarevic, Emma Donoghue, Or Duek, Guy-Loup Dulière, Adelaida Dzeko, George Eapen, Carolyn A Emery, Shane English, Patrick Esser, Erzsébet Ezer, Martin Fabricius, Junfeng Feng, Dean Fergusson, Anthony Figaji, Joanne Fleming, Kelly Foks, Gilles Francony, Stephen Freedman, Ulderico Freo, Shirin K Frisvold, Isabelle Gagnon, Damien Galanaud, Dashiell Gantner, Benoit Giraud, Ben Glocker, Jagoš Golubovic, Pedro A Gómez López, Wayne A Gordon, Primoz Gradisek, Jocelyn Gravel, Donald Griesdale, Francesca Grossi, Juanita A Haagsma, Asta Kristine Håberg, Iain Haitsma, Wim Van Hecke, Raimund Helbok, Eirik Helseth, Caroline van Heugten, Cornelia Hoedemaekers, Stefan Höfer, Lindsay Horton, Jiyuan Hui, Jilske Antonia Huijben, Peter J Hutchinson, Bram Jacobs, Mathieu van der Jagt, Stefan Jankowski, Koen Janssens, Bojan Jelaca, Kelly M Jones, Konstantinos Kamnitsas, Rafael Kaps, Mladen Karan, Ari Katila, Kirsi-Maija Kaukonen, Véronique De Keyser, Riku Kivisaari, Angelos G Kolias, Bálint Kolumbán, Ksenija Kolundžija, Daniel Kondziella, Lars-Owe Koskinen, Noémi Kovács, Andreas Kramer, Demitri Kutsogiannis, Theodoros Kyprianou, Alfonso Lagares, François Lamontagne, Roberto Latini, François Lauzier, Isaac Lazar, Christian Ledig, Rolf Lefering, Valerie Legrand, Leon Levi, Roger Lightfoot, Angels Lozano, Stephen MacDonald, Sebastian Major, Alex Manara, Pauline Manhes, Hugues Maréchal, Costanza Martino, Alessandro Masala, Serge Masson, Julia Mattern, Bradford McFadyen, Catherine McMahon, Maureen Meade, Béla Melegh, Tomas Menovsky, Lynne Moore, Marta Morgado Correia, Maria Cristina Morganti-Kossmann, Holger Muehlan, Pratik Mukherjee, Lynnette Murray, Joukje van der Naalt, Ancuta Negru, David Nelson, Daan Nieboer, Quentin Noirhomme, József Nyirádi, Mauro Oddo, David O Okonkwo, Annemarie W Oldenbeuving, Fabrizio Ortolano, Martin Osmond, Jean-François Payen, Vincent Perlbarg, Paolo Persona, Nicolas Pichon, Anna Piippo-Karjalainen, Sébastien Pili-Floury, Matti Pirinen, Horia Ple, Maria Antonia Poca, Jussi Posti, Dominique Van Praag, Alain Ptito, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Ruben G L Real, Nick Reed, Jonathan Rhodes, Claudia Robertson, Saulius Rocka, Cecilie Røe, Olav Røise, Gerwin Roks, Jonathan Rosand, Jeffrey V Rosenfeld, Christina Rosenlund, Guy Rosenthal, Sandra Rossi, Daniel Rueckert, Godard C W de Ruiter, Marco Sacchi, Barbara J Sahakian, Juan Sahuquillo, Oliver Sakowitz, Gerardo Salvato, Renán Sánchez-Porras, János Sándor, Grinder Sangha, Nadine Schäfer, Silke Schmidt, Kathryn J Schneider, David Schnyer, Herbert Schöhl, Guus G Schoonman, Rico Frederik Schou, Özcan Sir, Toril Skandsen, Dirk Smeets, Abayomi Sorinola, Emmanuel Stamatakis, Ana Stevanovic, Robert D Stevens, Nina Sundström, Fabio Silvio Taccone, Riikka Takala, Päivi Tanskanen, Mark Steven Taylor, Ralph Telgmann, Nancy Temkin, Guido Teodorani, Matt Thomas, Christos M Tolias, Tony Trapani, Alexis Turgeon, Peter Vajkoczy, Alex B Valadka, Egils Valeinis, Shirley Vallance, Zoltán Vámos, Alessia Vargiolu, Emmanuel Vega, Jan Verheyden, Anne Vik, Rimantas Vilcinis, Carmen Vleggeert-Lankamp, Lidia Vogt, Victor Volovici, Daphne C Voormolen, Peter Vulekovic, Thijs Vande Vyvere, Julia Van Waesberghe, Lars Wessels, Eno Wildschut, Guy Williams, Maren K L Winkler, Stefan Wolf, Gordon Wood, Nektaria Xirouchaki, Alexander Younsi, Menashe Zaaroor, Veronika Zelinkova, Roger Zemek, Fabrizio Zumbo
    更新日期:2017-11-07
  • Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-06
    Ivo N van Schaik, Vera Bril, Nan van Geloven, Hans-Peter Hartung, Richard A Lewis, Gen Sobue, John-Philip Lawo, Michaela Praus, Orell Mielke, Billie L Durn, David R Cornblath, Ingemar S J Merkies, A. Sabet, K. George, L. Roberts, R. Carne, S. Blum, R. Henderson, P. Van Damme, J. Demeestere, S. Larue, C. D'Amour, V. Bril, A. Breiner, P. Kunc, M. Valis, J. Sussova, T. Kalous, R. Talab, M. Bednar, T. Toomsoo, I. Rubanovits, K. Gross-Paju, U. Sorro, M. Saarela, M. Auranen, J. Pouget, S. Attarian, G. Le Masson, A. Wielanek-Bachelet, C. Desnuelle, E. Delmont, P. Clavelou, D. Aufauvre, J. Schmidt, J. Zschuentssch, C. Sommer, D. Kramer, O. Hoffmann, C. Goerlitz, J. Haas, M. Chatzopoulos, R. Yoon, R. Gold, P. Berlit, A. Jaspert-Grehl, D. Liebetanz, A. Kutschenko, M. Stangel, C. Trebst, P. Baum, F. Bergh, J. Klehmet, A. Meisel, F. Klostermann, J. Oechtering, H. Lehmann, M. Schroeter, T. Hagenacker, D. Mueller, A. Sperfeld, F. Bethke, V. Drory, A. Algom, D. Yarnitsky, B. Murinson, A. Di Muzio, F. Ciccocioppo, S. Sorbi, S. Mata, A. Schenone, M. Grandis, G. Lauria, D. Cazzato, G. Antonini, S. Morino, D. Cocito, M. Zibetti, T. Yokota, T. Ohkubo, T. Kanda, M. Kawai, K. Kaida, H. Onoue, S. Kuwabara, M. Mori, M. Iijima, K. Ohyama, M. Baba, M. Tomiyama, K. Nishiyama, T. Akutsu, K. Yokoyama, K. Kanai, I.N. van Schaik, F. Eftimov, N.C. Notermans, N. Visser, C. Faber, J. Hoeijmakers, K. Rejdak, U. Chyrchel-Paszkiewicz, C. Casanovas Pons, M. Alberti Aguiló, J. Gamez Carbonell, M. Figueras, C. Marquez Infante, S. Benitez Rivero, M. Lunn, J. Morrow, D. Gosal, T. Lavin, I. Melamed, A. Testori, S. Ajroud-Driss, D. Menichella, E. Simpson, E. Chi-Ho Lai, M. Dimachkie, R.J. Barohn, S. Beydoun, H. Johl, D. Lange, A. Shtilbans, S. Muley, S. Ladha, M. Freimer, J. Kissel, N. Latov, R. Chin, E. Ubogu, S. Mumfrey, T. Rao, P. MacDonald, K. Sharma, G. Gonzalez, J. Allen, D. Walk, L. Hobson-Webb, K. Gable
    更新日期:2017-11-07
  • 24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-30
    Hilkka Soininen, Alina Solomon, Pieter Jelle Visser, Suzanne B Hendrix, Kaj Blennow, Miia Kivipelto, Tobias Hartmann, Ilona Hallikainen, Merja Hallikainen, Seppo Helisalmi, Tarja Lappalainen, Yawu Liu, Teemu Paajanen, Lars-Olof Wahlund, Yvonne Freund-Levi, Niels Andreasen, Göran Hagman, Stina Lindblom, Klaus Fassbender, Matthias Riemenschneider, Marcus OW Grimm, Aline Klees-Rollmann, Maxine Luley, Epameinondas Lyros, Robert Schomburg, Jennifer Kennel, Daniela Ramelli, Lutz Frölich, Lucrezia Hausner, Christoph Laske, Thomas Leyhe, Christian Mychajliw, Niklas Koehler, Stephan Schiekofer, Hans Klünemann, Johannes Schröder, Dieter Lütjohann, Philip Scheltens, Ineke van Rossum, Nienke Scheltens, Daniela Bertens, Mara ten Kate, Frederik Barkhof, Johanna ML Henselmans, Gerwin Roks, Anneke MJ van Hees, Noel Ellison
    更新日期:2017-10-31
  • Targeting prodromal Alzheimer's disease: too late for prevention?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-30
    Hussein N Yassine

    Prodromal Alzheimer's disease is a novel area of research, with clinical research definitions still under development. The LipiDiDiet trial,1 published in The Lancet Neurology, was one of the first completed trials based on the International Working Group (IWG-1) criteria for prodromal Alzheimer's disease.2 The study was a non-pharmacological intervention (medical food Souvenaid) in prodromal Alzheimer's disease.

    更新日期:2017-10-31
  • Neurodegeneration in histiocytoses might start in utero
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-27
    Julien Haroche, Fleur Cohen-Aubart, Jean-François Emile, Jean Donadieu, Zahir Amoura

    Histiocytic disorders, such as Langerhans cell histiocytosis and Erdheim-Chester disease, are characterised by inflammation and accumulation of cells derived from the monocyte and macrophage lineages, resulting in tissue damage.1 Neurodegenerative lesions in Langerhans cell histiocytosis are a devastating type of CNS involvement—different from tumour infiltration—in which patients present with progressive symmetric cerebellar syndrome, tetrapyramidal syndrome with or without motor deficits, pseudobulbar palsy, or cognitive impairment.

    更新日期:2017-10-28
  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-20
    James F Howard, Kimiaki Utsugisawa, Michael Benatar, Hiroyuki Murai, Richard J Barohn, Isabel Illa, Saiju Jacob, John Vissing, Ted M Burns, John T Kissel, Srikanth Muppidi, Richard J Nowak, Fanny O'Brien, Jing-Jing Wang, Renato Mantegazza, Claudio Gabriel Mazia, Miguel Wilken, Carolina Ortea, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Gonzalo Vidal, Alejandra Dalila Garcia, Phillipa Lamont, Wai-Kuen Leong, Heidi Boterhoven, Beverly Fyfe, Leslie Roberts, Mahi Jasinarachchi, Natasha Willlems, Julia Wanschitz, Wolfgang Löscher, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Linda Wagemaekers, Delphine Mahieu, Philip Van Damme, Charlotte Smetcoren, Olivier Stevens, Sarah Verjans, Ann D'Hondt, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Rosa Hasan, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Ana Paula Melo, Rosana Rocha, Bruno Rosa, Thabata Veiga, Luiz Augusto da Silva, Jordana Gonçalves Geraldo, Maria da Penha Morita Ananias, Erica Nogueira Coelho, Gabriel Paiva, Marina Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Erica Coelho, Luciana Renata Cubas Volpe, Gustavo Duran, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Luciana Souza Duca, Tomás Augusto Suriane Fialho, Maurício André Gheller Friedrich, Alexandre Guerreiro, Henrique Mohr, Maurer Pereira Martins, Daiane da Cruz Pacheco, Ana Paula Macagnan, Aline de Cassia Santos, Acary Souza Bulle Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Valeria Cavalcante Lino, Wladimir Pinto, Carolina Miranda, Fernanda Carrara, Iandra Souza, Angela Genge, Rami Massie, Natasha Campbell, Vera Bril, Hans Katzberg, Mehran Soltani, Eduardo Ng, Zaeem Siddiqi, Celile Phan, Derrick Blackmore, Stanislav Vohanka, Josef Bednarik, Magda Chmelikova, Marek Cierny, Stanislava Toncrova, Jana Junkerova, Barbora Kurkova, Katarina Reguliova, Olga Zapletalova, Jiri Pitha, Iveta Novakova, Michaela Tyblova, Marcela Wolfova, Ivana Jurajdova, Henning Andersen, Thomas Harbo, Lotte Vinge, Anita Mogensen, Joan Højgaard, Nanna Witting, Anne Mette Autzen, Jane Pedersen, Markus Färkkilä, Sari Atula, Anne Nyrhinen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Jaana Eriksson, Tuula Harrison, Claude Desnuelle, Sabrina Sacconi, Marie-Hélène Soriani, Sonia Decressac, Julie Moutarde, Pauline Lahaut, Guilhem Solé, Gwendal Le Masson, Anne-Cécile Wielanek-Bachelet, Morgane Gaboreau, Caroline Moreau, Amy Wilson, Christophe Vial, Françoise Bouhour, Helene Gervais-Bernard, Hélène Merle, Caroline Hourquin, Arnaud Lacour, Olivier Outteryck, Patrick Vermersch, Hélène Zephir, Edouard Millois, Michel Deneve, Fabienne Deruelle, Benedikt Schoser, Stephan Wenninger, Martin Stangel, Sascha Alvermann, Stefan Gingele, Thomas Skripuletz, Kurt-Wolfram Suehs, Corinna Trebst, Karin Fricke, Sotirios Papagiannopoulos, Sevasti Bostantzopoulou, Nicholas Vlaikidis, Martha Zampaki, Nikoletta Papadopoulou, Dimos-Dimitrios Mitsikostas, Eleni Kasioti, Efstathia Mitropoulou, Despoina Charalambous, Csilla Rozsa, Melinda Horvath, Gabor Lovas, Judit Matolcsi, Gyorgyi Szabo, Brigitta Szabadosne, Laszlo Vecsei, Livia Dezsi, Edina Varga, Monika Konyane, Bella Gross, Olga Azrilin, Nelly Greenbereg, Hila Bali Kuperman, Giovanni Antonini, Antoneela di Pasquale, Matteo Garibaldi, Stefania Morina, Fernanda Troili, Antonella Di Pasquale, Matteo Garibaldi, Alessandro Filla, Teresa Costabile, Enrico Marano, Francesco Sacca, Angela Marsil, Giorgia Puorro, Michelangelo Maestri Tassoni, Anna De Rosa, Silvia Bonanno, Carlo Antozzi, Lorenzo Maggi, Angela Campanella, Corrado Angelini, Paola Cudia, Valentina Pegoraro, Elena Pinzan, Francesca Bevilacqua, Daniele Orrico, Domenico Marco Bonifati, Amelia Evoli, Paolo Emilio Alboini, Valentina D'Amato, Raffaele Iorio, Maurizio Inghilleri, Laura Fionda, Vittorio Frasca, Elena Giacomelli, Maria Gori, Diego Lopergolo, Emanuela Onesti, Vittorio Frasca, Maria Gabriele, Francesco Patti, Andrea Salvatore Caramma, Silvia Messina, Ester Reggio, Cinzia Caserta, Akiyuki Uzawa, Tetsuya Kanai, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Yuriko Nagane, Ikuko Kamegamori, Yuko Fujii, Kazumi Futono, Tomoko Tsuda, Yuka Saito, Hidekazu Suzuki, Miyuki Morikawa, Makoto Samukawa, Sachiko Kamakura, Hirokazu Shiraishi, Teiichiro Mitazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Tomomi Kobashikawa, Megumi Koga, Yasuko Maeda, Kazumi Takada, Mihoko Takada, Yumi Yamashita, Seiko Yoshida, Yasushi Suzuki, Tetsuya Akiyama, Koichi Narikawa, Kenichi Tsukita, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Hidenori Matsuo, Takayasu Fukudome, Yuichiro Gondo, Yasuhiro Maeda, Akiko Nagaishi, Shunya Nakane, Yoshinori Okubo, Meinoshin Okumura, Soichiro Funaka, Tomohiro Kawamura, Masayuki Makamori, Masanori Takahashi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Namie Taichi, Emiko Tsuda, Takashi Hayashi, Shin Hisahara, Tomihiro Imai, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shun Shimohama, Shuichiro Suzuki, Daisuke Yamamoto, Shingo Konno, Tomomi Imamura, Masashi Inoue, Mayumi Murata, Hiroshi Nakazora, Ritsu Nakayama, Yasuko Ikeda, Miki Ogawa, Maoko Shirane, Takashi Kanda, Motoharu Kawai, Michiaki Koga, Junichi Ogasawara, Masatoshi Omoto, Yasuteru Sano, Hideki Arima, Sachie Fukui, Shigemi Shimose, Hirokazu Shinozaki, Masanori Watanabe, Chieko Yoshikawa, Anneke van der Kooi, Marianne de Visser, Tamar Gibson, Jos Maessen, Marc de Baets, Catherine Faber, Maria Johanna Keijzers, Monique Miesen, Anna Kostera-Pruszczyk, Anna Kaminska, Byung-Jo Kim, Chang Nyoung Lee, Yong Seo Koo, Hung Youl Seok, Hoo Nam Kang, HyeJin Ra, Byoung Joon Kim, Eun Bin Cho, HyeLim Lee, Ju-Hong Min, Jinmyoung Seok, Da Yoon Koh, JuYoung Kwon, JiEun Lee, SangAe Park, Yoon-Ho Hong, Jae-Sung Lim, MiRi Kim, Seung Min Kim, Yool-hee Kim, Hyung Seok Lee, Ha Young Shin, Eun Bi Hwang, MiJu Shin, Denis Sazonov, Asya Yarmoschuk, Larisa Babenko, Nadezhda Malkova, Anna Melnikova, Denis Korobko, Evgeniya Kosykh, Dmitry Pokhabov, Yulia Nesterova, Vladislav Abramov, Victor Balyazin, Carlos Casasnovas Pons, Maria Alberti Aguilo, Christian Homedes-Pedret, Natalia Julia Palacios, Ana Lazaro, Exuperio Diez Tejedor, Mireya Fernandez-Fournier, Pedro Lopez Ruiz, Francisco Javier Rodriguez de Rivera, Maria Salvado Figueras, Josep Gamez, Maria Salvado, Elena Cortes Vicente, Jordi Diaz-Manera, Luis Querol Gutierrez, Ricardo Rojas Garcia, Nuria Vidal, Elisabet Arribas-Ibar, Fredrik Piehl, Albert Hietala, Lena Bjarbo, Christopher Lindberg, Daniel Jons, Blanka Andersson, Ihsan Sengun, Pinar Ozcelik, Celal Tuga, Muzeyyen Ugur, Cavit Boz, Didem Altiparmak, Sibel Gazioglu, Cigdem Ozen Aydin, Sevim Erdem-Ozdamar, Can Ebru Bekircan-Kurt, Ezgi Yilmaz, Nazire Pinar Acar, Yagmur Caliskan, Husnu Efendi, Seda Aydinlik, Hakan Cavus, Cansu Semiz, Ozlem Tun, Murat Terzi, Baki Dogan, Musa Kazim Onar, Sedat Sen, Tugce Kirbas Cavdar, Fiona Norwood, Aikaterini Dimitriou, Jakit Gollogly, Mohamed Mahdi-Rogers, Arshira Seddigh, Gal Maier, Faisal Sohail, Sivakumar Sathasivam, Heike Arndt, Debbie Davies, Dave Watling, Michael Rivner, J. Edward Hartmann, Brandy Quarles, Nicole Smalley, Anthony Amato, Thomas Cochrane, Mohammed Salajegheh, Kristen Roe, Katherine Amato, Shirli Toska, Gil Wolfe, Nicholas Silvestri, Kara Patrick, Karen Zakalik, Jonathan Katz, Robert Miller, Marguerite Engel, Elena Bravver, Benjamin Brooks, Sarah Plevka, Maryanne Burdette, Mohammad Sanjak, Megan Kramer, Joanne Nemeth, Clara Schommer, Vern Juel, Jeffrey Guptill, Lisa Hobson-Webb, Kate Beck, Donna Carnes, John Loor, Amanda Anderson, Dale Lange, Eliz Agopian, Jonathan Goldstein, Erin Manning, Lindsay Kaplan, Shara Holzberg, Nicole Kassebaum, Robert Pascuzzi, Cynthia Bodkin, John Kincaid, Riley Snook, Sandra Guinrich, Angela Micheels, Vinay Chaudhry, Andrea Corse, Betsy Mosmiller, Doreen Ho, Jayashri Srinivasan, Michael Vytopil, Nicholas Ventura, Stephanie Scala, Cynthia Carter, Craig Donahue, Carol Herbert, Elaine Weiner, Jonathan McKinnon, Laura Haar, Naya McKinnon, Karan Alcon, Kevin Daniels, Nadia Sattar, Dennis Jeffery, Kaitlyn McKenna, Amanda Guidon, William David, Christina Dheel, Mark Levine-Weinberg, Catherine Nigro, Ericka Simpson, Stanley H Appel, Eugene Lai, Luis Lay, Jr, Milvia Pleitez, Sharon Halton, Casey Faigle, Lisa Thompson, Mark Sivak, Susan Shin, Joan Bratton, Daniel Jacobs, Gavin Brown, Ibrez Bandukwala, Morris Brown, Jennifer Kane, Ira Blount, Miriam Freimer, J. Chad Hoyle, Julie Agriesti, Julie Khoury, Tessa Marburger, Harpreet Kaur, Diana Dimitrova, Michelle Mellion, George Sachs, Brigid Crabtree, Roseann Keo, Ele Kim Perez, Sandra Taber, James Gilchrist, Angela Andoin, Taylor Darnell, Neelam Goyal, Sarada Sakamuri, Yuen T So, Lesly Welsh Welsh, Ratna Bhavaraju-Sanka, Alejandro Tobon Gonzalez, Floyd Jones, Amy Saklad, Sharon Nations, Jaya Trivedi, Steve Hopkins, Mohamed Kazamel, Mohammad Alsharabati, Liang Lu, Sandi Mumfrey-Thomas, Amy Woodall, David Richman, Janelle Butters, Molly Lindsay, Tahseen Mozaffar, Tiyonnoh Cash, Namita Goyal, Gulmohor Roy, Veena Mathew, Fatima Maqsood, Brian Minton, H. James Jones, Jeffrey Rosenfeld, Rebekah Garcia, Sonia Garcia, Laura Echevarria, Michael Pulley, Shachie Aranke, Alan Ross Berger, Jaimin Shah, Yasmeen Shabbir, Lisa Smith, Mary Varghese, Laurie Gutmann, Ludwig Gutmann, Andrea Swenson, Heena Olalde, Charlene Hafer-Macko, Justin Kwan, Lindsay Zilliox, Karen Callison, Beth DiSanzo, Kerry Naunton, Martin Bilsker, Khema Sharma, Eliana Reyes, Anne Cooley, Sara-Claude Michon, Julie Steele, Chafic Karam Karam, Manisha Chopra, Shawn Bird, Jacob Kaufman, Nichole Gallatti, Tuan Vu, Lara Katzin, Terry McClain, Brittany Harvey, Adam Hart, Kristin Huynh, Said Beydoun, Amaiak Chilingaryan, Brian Droker, Frank Lin, Akshay Shah, Anh Tran, Salma Akhter, Ali Malekniazi, Rup Tandan, Michael Hehir, Waqar Waheed, Shannon Lucy, Michael Weiss, Jane Distad, Sharon Downing, Susan Strom, Robert Lisak, Evanthia Bernitsas, Omar Khan, Shitiz Kumar Sriwastava, Alexandros Tselis, Kelly Jia, Tulio Bertorini, Thomas Arnold, Kendrick Henderson, Rekha Pillai, Ye Liu, Lauren Wheeler, Jasmine Hewlett, Mollie Vanderhook, Daniel Dicapua, Benison Keung, Aditya Kumar, Huned Patwa, Kimberly Robeson, Joan Nye, Hong Vu
    更新日期:2017-10-21
  • Eculizumab: a treatment option for mysthenia gravis?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-20
    Nils Erik Gilhus

    Eculizumab is an expensive, humanised monoclonal antibody against the terminal complement protein C5. The drug was patented in 2007, and has since been used and approved for two rare diseases, paroxysmal nocturnal haemoglobulinuria and atypical haemolytic ureamic syndrome. Additionally, eculizumab has been used off-label, which constitutes up to a half of its use in some countries,1 for at least 25 different conditions. Refractory and generalised myasthenia gravis with anti-acetylcholine receptor antibodies is a rare disease that involves the complement system and for which eculizumab has a potential effect.

    更新日期:2017-10-21
  • Corrections
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-16

    Terkelsen A J, Karlsson P, Lauria G, Freeman R, Finnerup N B, Jensen T S. The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes. Lancet Neurol 2017; 16: 934–44. The declaration of interests section of this article should have stated, “AJT has participated in an investigator-sponsored study provided by Sanofi Genzyme and Alynylam Pharmaceuticals.” This correction has been made to the online version as of Oct 16, 2017.

    更新日期:2017-10-17
  • The next generation of leaders advocating for brain health
    Lancet Neurol. (IF 26.284) Pub Date : 2017-10-16
    Dana Smith
    更新日期:2017-10-17
  • The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Astrid J Terkelsen, Páll Karlsson, Giuseppe Lauria, Roy Freeman, Nanna B Finnerup, Troels S Jensen
    更新日期:2017-10-11
  • Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Barbara Schormair, Chen Zhao, Steven Bell, Erik Tilch, Aaro V Salminen, Benno Pütz, Yves Dauvilliers, Ambra Stefani, Birgit Högl, Werner Poewe, David Kemlink, Karel Sonka, Cornelius G Bachmann, Walter Paulus, Claudia Trenkwalder, Wolfgang H Oertel, Magdolna Hornyak, Maris Teder-Laving, Andres Metspalu, Georgios M Hadjigeorgiou, Olli Polo, Ingo Fietze, Owen A Ross, Zbigniew Wszolek, Adam S Butterworth, Nicole Soranzo, Willem H Ouwehand, David J Roberts, John Danesh, Richard P Allen, Christopher J Earley, William G Ondo, Lan Xiong, Jacques Montplaisir, Ziv Gan-Or, Markus Perola, Pavel Vodicka, Christian Dina, Andre Franke, Lukas Tittmann, Alexandre F R Stewart, Svati H Shah, Christian Gieger, Annette Peters, Guy A Rouleau, Klaus Berger, Konrad Oexle, Emanuele Di Angelantonio, David A Hinds, Bertram Müller-Myhsok, Juliane Winkelmann, B Balkau, P Ducimetière, E Eschwège, F Rancière, F Alhenc-Gelas, Y Gallois, A Girault, F Fumeron, M Marre, R Roussel, F Bonnet, A Bonnefond, S Cauchi, P Froguel, J Cogneau, C Born, E Caces, M Cailleau, O Lantieri, JG Moreau, F Rakotozafy, J Tichet, S Vol, Michelle Agee, Babak Alipanahi, Adam Auton, Robert K Bell, Katarzyna Bryc, Sarah L Elson, Pierre Fontanillas, Nicholas A Furlotte, David A Hinds, Bethann S Hromatka, Karen E Huber, Aaron Kleinman, Nadia K Litterman, Matthew H McIntyre, Joanna L Mountain, Carrie AM Northover, Steven J Pitts, J Fah Sathirapongsasuti, Olga V Sazonova, Janie F Shelton, Suyash Shringarpure, Chao Tian, Joyce Y Tung, Vladimir Vacic, Catherine H Wilson
    更新日期:2017-10-11
  • Andrew Maas (and the bird on his shoulder)
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Adrian Burton
    更新日期:2017-10-11
  • Trying to change the stroke landscape in Nigeria
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Adrian Burton
    更新日期:2017-10-11
  • Palliative care in neurology
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    David Oliver, Marianne de Visser, Raymond Voltz

    We congratulate the editors of The Lancet Neurology for highlighting the topic of palliative care in neurology in their Editorial,1 which was prompted by the European Association for Neuro-Oncology guideline2 on palliative care in glioblastoma. As the coordinators of the earlier consensus review3 on the development of palliative care for patients with chronic and progressive neurological disease, developed by the European Academy of Neurology and the European Association for Palliative Care, we would like to suggest that there is a need for further development of disease-specific guidelines, in neurology and other fields, and consideration of the collaboration of these specialties.

    更新日期:2017-10-11
  • Palliative care in neurology
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Wing Loong Cheong, Daniel D Reidpath

    A recent Editorial in The Lancet Neurology1 highlighted the importance of palliative care for patients with progressive neurological diseases and the requirement for increased funding and research. Because data on prevalence, incidence, and stage of disease in many low-income and middle-income countries is scarce, proxy data is used to estimate palliative care needs. One method of estimation proposed by WHO and the World Palliative Care Alliance relies on mortality data.2 The number of patients with a progressive neurological disease who require palliative care is estimated by the number of deaths attributable to a particular cause and multiplied by the prevalence of pain in that patient group.

    更新日期:2017-10-11
  • Challenges and unfulfilled promises in Parkinson's disease
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    A Jon Stoessl

    Neurodegenerative disorders take a heavy toll on individuals who have a diagnosis and their family and loved ones, and place an enormous economic burden on the health-care system. Parkinson's disease is amenable to reasonably, albeit incompletely, effective therapies to manage symptoms, but to date, no treatment has been found to slow its progression. Therefore, any potentially disease-modifying treatment is met with great enthusiasm.

    更新日期:2017-10-11
  • Pathology and hippocampal atrophy in Alzheimer's disease
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Glenda Halliday
    更新日期:2017-10-11
  • Restless legs syndrome: is it all in the genes?
    Lancet Neurol. (IF 26.284) Pub Date : 2017-11-01
    Sonja W Scholz
    更新日期:2017-10-11
Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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