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Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-19 Niloufar Salehi, Jozef Al-Gousous, Bart Hens, Gordon L. Amidon, Robert M. Ziff, Gregory E. Amidon
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Macrophages and Natural Killers Degrade α-Synuclein Aggregates Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-18 Mikhail Matveyenka, Kiryl Zhaliazka, Dmitry Kurouski
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Recent Progress of Small Interfering RNA Delivery on the Market and Clinical Stage Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-17 Fan Guo, Yan Li, Wenjun Yu, Yuanlei Fu, Jing Zhang, Haiqiang Cao
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Voices in Molecular Pharmaceutics: Meet Professor Keisuke Ueda, Who Scrutinizes the Molecular-Level Properties of Drugs and Formulations Using NMR Spectroscopy Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-17 Keisuke Ueda
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Feasibility Study of Single-Photon Emission Computed Tomography with Iodine-123 Labeled Metaiodobenzylguanidine for Preclinical Evaluation of Labetalol as a β-Adrenergic Receptor Blocker Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-16 Yiseul Choi, Eun Sang Lee, Sang-Keun Woo, Kyo Chul Lee, Hye Kyung Chung, Joo Hyun Kang
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Insulin Signaling Differentially Regulates the Trafficking of Insulin and Amyloid Beta Peptides at the Blood–Brain Barrier Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-16 Andrew L. Zhou, Suresh K. Swaminathan, Vrishali S. Salian, Lushan Wang, Geoffry L. Curran, Hoon-Ki Min, Val J. Lowe, Karunya K. Kandimalla
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Transfer of ANS-Like Drugs from Micellar Drug Delivery Systems to Albumin Is Highly Favorable and Protected from Competition with Surfactant by “Reserved” Binding Sites Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-16 Iulia Carabadjac, Leonie C. Vormittag, Thomas Muszer, Jakob Wuth, Maximilian H. Ulbrich, Heiko Heerklotz
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Customizable Porphyrin Platform Enables Folate Receptor PET Imaging Using Copper-64 Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-16 Hailey A. Houson, Zhiyuan Wu, Phuong-Lien Doan Cao, Jonathan S. Lindsey, Suzanne E. Lapi
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Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-15 Xueyu Pu, Yuanyuan Wang, Xi Wang, Xiaoqing Sang, Miaomiao Jiang, DaWei Qi, Xin Zhao, Rong Chen, Jianwei Li, Xiang Liu, Zhidong Liu, Jian Yang
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Blue-Light-Activated Water-Soluble Sn(IV)-Porphyrins for Antibacterial Photodynamic Therapy (aPDT) against Drug-Resistant Bacterial Pathogens Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-15 T. Nagarajan, M. P. Gayathri, John Mack, Tebello Nyokong, Sutharsan Govindarajan, Balaji Babu
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Phospholipid Type Regulates Protein Corona Composition and In Vivo Performance of Lipid Nanodiscs Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-12 Feng Pan, Mengyuan Liu, Guanghui Li, Boqian Chen, Yuxiu Chu, Yang Yang, Ercan Wu, Yifei Yu, Shiqi Lin, Tianhao Ding, Xiaoli Wei, Changyou Zhan, Jun Qian
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Synthesis, Screening, and Evaluation of Theranostic Molecular CPCR4-Based Probe Targeting CXCR4 Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-12 Tingting Yang, Dai Shi, Qingyu Lin, Hua Shen, Hui Tan, Yuxia Liu, Hongcheng Shi, Dengfeng Cheng
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Design, Synthesis, and Evaluation of [18F]BIBD-300 as a Positron Emission Tomography Tracer for Poly(ADP-Ribose) Polymerase-1 Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-12 Wei Zheng, Yong Huang, Yi Xie, Tingyu Yang, Xuebo Cheng, Hualong Chen, Chengze Li, Zeng Jiang, Ziyue Yu, Zhongjing Li, Lu Zhang, Leilei Yuan, Yajing Liu, Ying Liang, Zehui Wu
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Transdermal Delivery of Pramipexole Using Microneedle Technology for the Potential Treatment of Parkinson’s Disease Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-11 Mary B. McGuckin, Aaron R.J. Hutton, Ellie R. Davis, Akmal H.B. Sabri, Anastasia Ripolin, Achmad Himawan, Yara A. Naser, Rand Ghanma, Brett Greer, Helen O. McCarthy, Alejandro J. Paredes, Eneko Larrañeta, Ryan F. Donnelly
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Physiologically Based Biopharmaceutics Modeling (PBBM): Best Practices for Drug Product Quality, Regulatory and Industry Perspectives: 2023 Workshop Summary Report Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-10 Claire Mackie, Sumit Arora, Paul Seo, Rebecca Moody, Bhagwant Rege, Xavier Pepin, Tycho Heimbach, Christer Tannergren, Amitava Mitra, Sandra Suarez-Sharp, Luiza Novaes Borges, Shinichi Kijima, Evangelos Kotzagiorgis, Maria Malamatari, Shereeni Veerasingham, James E. Polli, Gregory Rullo
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Enhanced Theranostic Efficacy of 89Zr and 177Lu-Labeled Aflibercept in Renal Cancer: A Viable Option for Clinical Practice Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-08 Zhao Chen, Qi Yang, Lele Song, Yongkang Qiu, Tianyao Wang, Sitong Wu, Wenpeng Huang, Xinyao Sun, Aixiang Wang, Lei Kang
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The Effect of Lipid Composition on the Liposomal Delivery of Camptothecin Developed by Active Click Loading Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-05 Lei Xie, Qian Zhang, Qian Zhu, Yang Wang, Shuijiao Niu, Xinyue Zhang, Yuting Huang, Jiayao Li, Xiaoxue Liu, Zhiyuan Xue, Xia Zhao, Yaxin Zheng
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Quantifying the Lymphatic Transport of Model Therapeutics from the Brain in Rats Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-05 Thu A Hoang, Gracia Gracia, Enyuan Cao, Joseph A Nicolazzo, Natalie L Trevaskis
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Concentration-Dependent Diffusion of Monoclonal Antibodies: Underlying Mechanisms of Anomalous Diffusion Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-04 Gaurav Kumar, Arezoo M. Ardekani
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Synthesis and Evaluation of Radiogallium Labeled Bone-Imaging Probes Using Oligo-γ-Carboxy Glutamic Acid Peptides as Carriers to Bone Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-04 Kazuma Ogawa, Kota Nishizawa, Kenji Mishiro, Nurmaya Effendi, Takeshi Fuchigami, Masayuki Munekane, Hiroshi Wakabayashi, Seigo Kinuya
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Role for Carboxylic Acid Moiety in NSAIDs: Favoring the Binding at Site II of Bovine Serum Albumin Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-04 Luiza de Carvalho Bertozo, Hugo Cesar Tadeu, Anila Sebastian, Martyna Maszota-Zieleniak, Sergey A. Samsonov, Valdecir Farias Ximenes
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In Vitro Simulation of the Fasted Gastric Conditions and Their Variability to Elucidate Contrasting Properties of the Marketed Dabigatran Etexilate Pellet-Filled Capsules and Loose Pellets Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-03 Marcela Staniszewska, Daria Myslitska, Michał Romański, Sebastian Polak, Grzegorz Garbacz, Justyna Dobosz, Michał Smoleński, Jadwiga Paszkowska, Dorota Danielak
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Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the 99mTc-Based Imaging of HER2-Expressing Malignant Tumors Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-04-01 Maria Larkina, Ruslan Varvashenya, Feruza Yuldasheva, Evgenii Plotnikov, Ekaterina Bezverkhniaia, Maria Tretyakova, Roman Zelchan, Alexey Schulga, Elena Konovalova, Anzhelika Vorobyeva, Mikhail Belousov, Anna Orlova, Vladimir Tolmachev, Sergey Deyev
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Synthesis and Evaluation of [18F]AlF-NOTA-c-DVAP: A Novel PET Probe for Imaging GRP78 in Cancer Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-30 Jiawen Huang, Lu Bai, Dazhi Shi, Wenhao Jiang, Pan Chen, Ye Dong, Xiaojun Zhang, Jiangling Peng, Jinqiang Hou, Yujing Lu, Xiaohong Huang, Ganghua Tang, Shun Huang
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A Model Study to Assess Fibrillation and Product Stability to Support Peptide Drug Design Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-29 Harshil K. Renawala, Karthik B. Chandrababu, Katelyn J. Smith, Suzanne M. D’Addio, Elizabeth M. Topp
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Combination of Molecule-Targeted Therapy and Photodynamic Therapy Using Nanoformulated Verteporfin for Effective Uveal Melanoma Treatment Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-28 Meijiao Song, Lei Zhu, Lumeng Zhang, Xiaoguang Ge, Jinfeng Cao, Yong Teng, Rui Tian
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Characterization of Pediatric Rectal Absorption, Drug Disposition, and Sedation Level for Midazolam Gel Using Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-29 Jinying Zhu, Sufeng Zhou, Lu Wang, Yuqing Zhao, Jie Wang, Tangping Zhao, Tongtong Li, Feng Shao
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Investigation of Optimum Production Conditions and the Stability of β-Cyclodextrin–Perfluorocarbon Nanocone Clusters for Histotripsy Applications Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-29 Waleed Mustafa, Sarah Hall, Laura Huynh, Rachel Mannasse, Serter Luleburgaz, Eli Vlaisavljevich, Yasemin Yuksel Durmaz
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Dual Functionality of Poloxamer 188 in Freeze-Dried Protein Formulations: A Stabilizer in Frozen Solutions and a Bulking Agent in Lyophiles Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-29 Jinghan Li, Bhushan Munjal, Chaowang Zeng, Raj Suryanarayanan
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Potentiation of Brain Bioavailability Using Thermoreversible Cubosomal Formulation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-28 Harshvardhan Jain, Bala Prabhakar, Pravin K. Shende
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Combination Nano-Delivery Systems Remodel the Immunosuppressive Tumor Microenvironment for Metastatic Triple-Negative Breast Cancer Therapy Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-27 Liya Bai, Hui Liu, Ran You, Xiaoyu Jiang, Tao Zhang, Yunan Li, Tianhe Shan, Zhanyin Qian, Yinsong Wang, Yuanyuan Liu, Chunyu Li
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Correction to “PET Imaging of Peptide Probe Al[18F]F-NOTA-PCP1 for Monitoring the Engagement of PD-L1 Antibodies in Tumors” Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-26 Yang Zhang, Yong Wang, Yunhao Chen, Xingchen Ding, Shijie Wang, Wei Liu, Zhiguo Liu, Man Hu
We have adjusted the sequence of authors to Yang Zhang,† Yong Wang,† Yunhao Chen, Xingchen Ding, Shijie Wang, Wei Liu, Zhiguo Liu,* and Man Hu*. This change is reflected in the authorship of this Correction. This article has not yet been cited by other publications.
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Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-26 Baron J. Bechtold, Katherine D. Lynch, Victoria O. Oyanna, M. Ridge Call, Tyler N. Graf, Nicholas H. Oberlies, John D. Clarke
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Preparation of Compound Salvia miltiorrhiza–Blumea balsamifera Nanoemulsion Gel and Its Effect on Hypertrophic Scars in the Rabbit Ear Model Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-25 Teng Chen, Zuhua Wang, Xingchu Gong, Jiaojiao Zhang, Ning Zhang, Jing Yang, Yue Zhu, Ying Zhou
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Voices in Molecular Pharmaceutics: Meet Professor Owen S. Fenton, Designer of Lipid Nanoparticles for Messenger RNA Delivery Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-25 Owen S. Fenton
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Clues to the Design of Aggregation-Resistant Insulin from Proline Scanning of Highly Amyloidogenic Peptides Derived from the N-Terminal Segment of the A-Chain Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-25 Wojciech Puławski, Robert Dec, Wojciech Dzwolak
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Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen–Deuterium Exchange Mass Spectrometry Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-22 Victoria E. Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M. Topp, Paul Matejtschuk, Paul A. Dalby
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An Artificial Gut/Absorption Simulator: Understanding the Impact of Absorption on In Vitro Dissolution, Speciation, and Precipitation of Amorphous Solid Dispersions Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-21 Krutika Meena Harish Jain, Hao Helen Hou, Ronald A. Siegel
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Networking in the Pharmaceutical Sciences Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-21 Lynne S. Taylor
As an introvert, walking into a crowded room full of strangers fills me with dread. Small talk and being able to connect with new people do not come naturally to me. I suspect many others feel the same way. In contrast, my extrovert colleagues breeze happily through the crowds, chatting with ease to all and sundry, becoming energized by making new contacts. Whatever your personality type, the ability
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Proving the Antimicrobial Therapeutic Activity on a New Copper–Thiosemicarbazone Complex Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-20 David Fabra, Georgiana Amariei, Daniel Ruiz-Camino, Ana I. Matesanz, Roberto Rosal, Adoracion G. Quiroga, Patricia Horcajada, Tania Hidalgo
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Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-19 Katie McCormick, Jorge Moreno Herrero, Heinrich Haas, Sarinj Fattah, Andreas Heise, Fergal J. O’Brien, Sally-Ann Cryan
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Quantitative Investigation of Intestinal Drug Absorption Enhancement by Drug-Rich Nanodroplets Generated via Liquid–Liquid Phase Separation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-19 Etsushi Yoshikawa, Keisuke Ueda, Rei Hakata, Kenjirou Higashi, Kunikazu Moribe
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Insights into Factors Affecting Ethylene-Vinyl Acetate Copolymer Crystallinity in Islatravir Implant Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-19 Xiaolong Zhu, Ashish Punia, Daniel Skomski, Yongchao Su, C. Scott Shultz, Morgan B. Giles, Nathan D. Rudd, Nisha Raman, Athanas Koynov, Matthew S. Lamm
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ROS-Responsive Bola-Lipid Nanoparticles as a Codelivery System for Gene/Photodynamic Combination Therapy Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-18 Rui-Mo Zhao, Qin-Fang Zhang, Xiao-Li Tian, Jia-Jia Chen, Xiao-Qi Yu, Ji Zhang
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Nuclear Localization Signal Enhances the Targeting and Therapeutic Efficacy of a Porphyrin-Based Molecular Cargo: A Systemic In Vitro and Ex Vivo Evaluation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-13 Naveen Kumar, Amit K. Sharma, Mohini Guleria, Sandeep B. Shelar, Avik Chakraborty, Sutapa Rakshit, Soumi Kolay, Drishty Satpati, Tapas Das
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Therapeutic Effect of a Novel M1 Macrophage-Targeted Nanodrug in Chronic Periodontitis Mice Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-13 Qiuye Chen, Yunshan Zhao, Chen Xie, Shiwang Wu, Weizhen Ji, Xu Xiao, Xu Zheng
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Drug Delivery Angle for Various Atherosclerosis and Aneurysm Percentages of the Carotid Artery Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-13 Ali Amani, Amir Hamzeh Farajollahi
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Neutrophil-Based Bionic Delivery System Breaks Through the Capillary Barrier of Liver Sinusoidal Endothelial Cells and Inhibits the Activation of Hepatic Stellate Cells Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-12 Dan Sun, Xiao Du, Xinyu Cao, Bingyu Wu, Shanshan Li, Yongmei Zhao, Tianqing Liu, Lixing Xu, Haiqin Huang
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Dissolution Mechanisms of Amorphous Solid Dispersions: Application of Ternary Phase Diagrams To Explain Release Behavior Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-12 Alexandru Deac, Christian Luebbert, Qingqing Qi, Reagan M. Courtney, Anura S. Indulkar, Yi Gao, Geoff G. Z. Zhang, Gabriele Sadowski, Lynne S. Taylor
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Correction to “Insights into the Structure of Sucralfate by Advanced Solid- and Liquid-State NMR” Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-12 Chaithanya Hareendran, Sapna Ravindranathan, T. G. Ajithkumar
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Second Near-Infrared Macrophage-Biomimetic Nanoprobes for Photoacoustic Imaging of Neuroinflammation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-11 Yingying Pan, Jingqin Chen, Yuling Zhang, Yaguang Ren, Zhifeng Wu, Qiang Xue, Silue Zeng, Chihua Fang, Hai Zhang, Lingyan Zhang, Chengbo Liu, Jie Zeng
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Nebulization and In Vitro Upper Airway Deposition of Liposomal Carrier Systems Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-11 Ondrej Mišík, Jana Kejíková, Ondřej Cejpek, Milan Malý, Adam Jugl, Miloslav Bělka, Filip Mravec, František Lízal
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Targeted Delivery of Catalase and Photosensitizer Ce6 by a Tumor-Specific Aptamer Is Effective against Bladder Cancer In Vivo Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-11 Yang Zhang, Ru Jia, Xiaoyi Wang, Yixuan Zhang, Jinhui Wu, Quansheng Yu, Qiang Lv, Chao Yan, Pengchao Li
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Deciphering the Lexicon of Protein Targets: A Review on Multifaceted Drug Discovery in the Era of Artificial Intelligence Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-11 Suvendu Nandi, Soumyadeep Bhaduri, Debraj Das, Priya Ghosh, Mahitosh Mandal, Pralay Mitra
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KRAS Mutation Detection with (2S,4R)-4-[18F]FGln for Noninvasive PDAC Diagnosis Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-08 Song Liu, Futao Liu, Xingguo Hou, Qian Zhang, Ya’nan Ren, Hua Zhu, Zhi Yang, Xiaoxia Xu
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Cell-Penetrating Peptides: Promising Therapeutics and Drug-Delivery Systems for Neurodegenerative Diseases Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-05 Mitra Pirhaghi, Fatemeh Mamashli, Faezeh Moosavi-Movahedi, Payam Arghavani, Ahmad Amiri, Bagher Davaeil, Mahya Mohammad-Zaheri, Zahra Mousavi-Jarrahi, Deepak Sharma, Ülo Langel, Daniel Erik Otzen, Ali Akbar Saboury
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Multimodal Theranostic Nanoparticles for Necrosis Targeting, Fluorescence/SPECT Imaging, and Radiotherapy of Residual Tumors after Hepatocellular Carcinoma Ablation Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-07 Han Bao, Ning Wang, Song Chen, Yang Wang, Haibo Shao, Yicheng Ni, Yukang Li, Xian Liu, Xiangjun Han
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18F-Labeled Amidobenzimidazole Analogue for Visualizing STING Expression in Tumor Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-06 Jianyang Fang, Jingru Zhang, Lingxin Meng, Huifeng Li, Dongsheng Xia, Yaoxuan Wang, Hao Chen, Zhenhuan Liao, Rongqiang Zhuang, Yesen Li, Xianzhong Zhang, Zhide Guo
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Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-05 Tejal Akbar, Pavel Gershkovich, Konstantinos Stamatopoulos, Penny A. Gowland, Snow Stolnik, James Butler, Luca Marciani
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Correction to “Reverse Iontophoresis: Noninvasive Assessment of Topical Drug Bioavailability” Mol. Pharmaceutics (IF 4.9) Pub Date : 2024-03-05 Kieran Moore, Sébastien Grégoire, Joan Eilstein, M. Begoña Delgado-Charro, Richard H. Guy
The units of In vitro CVT,0 and In vivo CVT,0 in Table 3 should both be μmol mL–1. The results, discussions, and conclusions in the original article are not affected by this correction. This article has not yet been cited by other publications.